Early Date Research Articles

A fresh perspective on advances in pancreatic cancer treatment over the past two decades

In the past two decades, significant advances have been made in the treatment of pancreatic cancer.Numerous first-line treatments, such as gemcitabine combined with erlotinib, gemcitabine combined with albumin-bound paclitaxel, FOLFIRINOX, and NALIRIFOX, have emerged;surgery-centered treatment has gradually become the mains clinical strategy.However, behind these achievements, the new drugs developed with substantial funding have not extended the median survival time of patients with advanced pancreatic cancer to more than one year; the 5-year survival rate for postoperative patients remains below 30%. While harboring hope and being proactive, researchers must also soberly reflect and continually reassess our direction, in anticipation of bringing tangible clinical benefits to pancreatic cancer patients at an early date.

Rhinosinusitis in children with acute respiratory infection: quality of life and features of drug therapy

BACKGROUND: The relevance of the study is due to limited information on the impact of various forms of rhinosinusitis that have arisen against the background of acute respiratory infection on the quality of life of children and effective treatment methods. AIM: To conduct a clinical assessment of the effect on the recovery time and quality of life in children with acute rhinosinusitis and exacerbation of polypous rhinosinusitis that occurred against the background of a respiratory infection, including antiviral drugs in complex treatment in the early stages. MATERIALS AND METHODS: A simple controlled randomized comparative clinical trial was conducted, involving 74 children aged 15 to 18 years. The clinical efficacy and safety of the use of antiviral drugs in complex therapy, which are neuraminidase inhibitors on the 5th, 7th and 10th days of treatment, were evaluated in comparison with groups receiving pentanedioic acid imidazolylethanamide. The inclusion criterion was acute rhinosinusitis and exacerbation of chronic polypous rhinosinusitis against the background of acute respiratory infection. To establish the diagnosis, an examination of ENT organs, computed tomography of the nose and paranasal sinuses were performed, patients subjectively assessed clinical complaints and quality of life in the Russian version of the standard form of the SF-36 questionnaire. RESULTS: Positive dynamics was noted in the early stages in the 2nd subgroup of the 1st group who took neuraminidase inhibitors in addition to complex therapy. Manifested by a decrease in the average score for VAS to 80.0%, difficulty in nasal breathing to 1.7 points on the 10th day of treatment, relative to those taking imidazolylethanamide pentanedioic acid, where there was a decrease in the average score for VAS by 22.4%, difficulty in nasal breathing to 2.54 points. A similar pattern was observed with nasal congestion, rhinorrhea, and quality of life indicators according to the SF-36 questionnaires. CONCLUSION: Improvement of clinical symptoms and quality of life indicators at an earlier date in children with polypous rhinosinusitis and acute rhinosinusitis against the background of a previous respiratory infection with the inclusion of neuraminidase inhibitors in complex therapy confirmed higher efficacy.

НОВІ ВІДКРИТТЯ, ПРОБЛЕМИ ДОСЛІДЖЕННЯ ТА ЗБЕРЕЖЕННЯ ПІДЗЕМНОЇ СПАДЩИНИ ДАВНЬОГО ГАЛИЧА

The long history of changing ideas is considered and the hypothesis of the urban structure of ancient Halych of the 12th-13th centuries is demonstrated. according to archaeological sources. Based on the analysis of stratigraphic, planning and construction-technological features, the relative chronology of the appearance of the 16 studied relics of monumental architecture was established. The earliest monuments of the first half of the 12th century are examined in detail: an ensemble of palace buildings with a post construction of log walls, the use of a plinth and a tin roof on Kryloska Hill, a complex of churches on Tsarynka, the Church of the Savior on Karpytsia Hill, as well as other objects, on which recent discoveries have been made. The appearance of early sacred objects outside the city is explained by the gradual Christianization of the population of Halych. Analysis of the construction periodization of the Dormition Cathedral in the middle of the 12th century. allows you to review its graphic reconstructions until now and raise the question of developing a new hypothesis of the three-dimensional appearance of the building during the first construction period, from which the recently found detail of a large alabaster ornamentally decorated capital with traces of false gilding comes from. The results of architectural and archaeological soundings at the outer contours of the foundations of the Panteleimon Church confirmed the presence of regular external protrusions of the foundations, which calibrates the construction of the object together with the early paleographic dates of the early 90s of the 12th century. Part makes it possible to argue the use of a measuring foot of 30 cm. Attention is drawn to the problems of preserving a number of known architectural and archaeological objects and the search for unknown monuments by non-invasive research methods.

Hydroxychloroquine and Chloroquine-Induced Cardiac Arrhythmias and Sudden Cardiac Death in Patients with Systemic Autoimmune Rheumatic Diseases: A Systematic Review and Meta-Analysis

Hydroxychloroquine (HCQ) and chloroquine (CQ) are foundational treatments for several systemic autoimmune rheumatic diseases, including systemic lupus erythematosus (SLE) and rheumatoid arthritis (RA). Concerns regarding the risk of cardiac arrhythmia and death have been raised, yet the burden of HCQ and CQ-related cardiac toxicities remains unclear. A systematic literature search was conducted in the MEDLINE and Embase databases for articles published between the earliest date and April 2023 reporting cardiac conduction abnormalities in patients with systemic autoimmune rheumatic diseases taking HCQ or CQ. Meta-analysis was performed to calculate the difference in mean QTc and odds ratio of prolonged QTc in those taking HCQ or CQ versus not. Of 2673 unique records, 34 met the inclusion criteria, including 70,609 subjects. Thirty-three studies reported outcomes in HCQ and 9 in CQ. Five studies reported outcomes in RA, 11 in SLE, and 18 in populations with mixed rheumatic diseases. Eleven studies reported mean QTc and OR for prolonged QTc for meta-analysis, all reporting outcomes in HCQ. There was a significant increase in mean QTc among HCQ users in patients with RA (10.29 ms, p = 0.458). There was no difference in mean QTc between HCQ and non-HCQ users in other systemic autoimmune rheumatic diseases. When rheumatic diseases were pooled, HCQ users were more likely to have prolonged QTc (odds ratio 1.57, 95%CI: 1.19, 2.08). QTc prolongation was more likely in patients with systemic autoimmune rheumatic diseases. Clinicians should be aware of potential adverse cardiac events of HCQ and consider QTc monitoring.

The Effect of Yoga Intervention on Psychological Symptoms, Health-Related Quality of Life, and Cardiovascular Risk Factors in People with Coronary Artery Disease: A Systematic Review and Meta-Analysis

Abstract Background: Whether yoga is effective in the cardiac rehabilitation of people with coronary artery disease (CAD) remains controversial. Objective: The aim of this study was to investigate the effects of yoga intervention on psychological symptoms, health-related quality of life (HRQoL), and major cardiovascular risk factors in people with CAD. Methods: We searched MEDLINE/PubMed, Cochrane, EMBASE, and Physiotherapy Evidence Database (from the earliest date available to July 2023). Mean difference (MD), standardized MD (SMD), and 95% confidence interval (CI) were calculated. Results: Seventeen studies, with 5,698 patients, met the study criteria. Compared to control (no exercise), yoga resulted in improved depression MD −0.83 (95% CI: −1.35 to −0.31), stress MD −3.83 (95% CI: −4.8 to 2.86), HRQoL SMD 1.48 (95% CI: 0.55 to 2.4), major cardiovascular risk factors (peak VO2 MD 1.7 mL/kg/min [95% CI: 0.2 to 3.3], systolic blood pressure MD −3.2 mmHg [95% CI: −5.9 to −0.5], and diastolic blood pressure MD −2.42 mmHg [95% CI: −4.08 to −0.76]). Conclusions: Yoga was effective in the improvement of psychological symptoms, HRQoL, and cardiovascular risk factors.

Surface heat fluxes at coarse blocky Murtèl rock glacier (Engadine, eastern Swiss Alps)

Abstract. We estimate the surface energy balance (SEB) of the Murtèl rock glacier, a seasonally snow-covered permafrost landform with a ventilated coarse blocky active layer (AL) located in the eastern Swiss Alps. We focus on the parameterisation of the turbulent heat fluxes. Seasonally contrasting atmospheric conditions occur in the Murtèl cirque, with downslope katabatic jets in winter and a strongly unstable atmosphere over the heated blocky surface in summer. We use a novel comprehensive sensor array both above the ground surface and in the coarse blocky AL to track the rapid coupling by convective heat and moisture fluxes between the atmosphere, the snow cover, and the AL for the time period September 2020–September 2022. The in situ sensor array includes a sonic anemometer for eddy-covariance flux above-ground and sub-surface long-wave radiation measurements in a natural cavity between the AL blocks. During the thaw seasons, the measurements suggest an efficient (∼ 90 %) export of the available net radiation by sensible and latent turbulent fluxes, thereby strongly limiting the heat available for melting ground ice. Turbulent export of heat and moisture drawn from the permeable AL contributes to the well-known insulating effect of the coarse blocky AL and partly explains the climate resiliency of rock glaciers. This self-cooling capacity is counteracted by an early snow melt-out date, exposing the low-albedo blocky surface to the intense June–July insolation and causing reduced evaporative cooling due to exacerbated moisture scarcity in the near-surface AL during dry spells. With climate change, earlier snowmelt and increased frequency, duration, and intensity of heat waves and droughts are projected. Regarding the parameterisation of the turbulent fluxes, we estimated the year-round turbulent fluxes using a modified Louis (1979) scheme. The monthly SEB is closed within 20 W m−2 except during the snowmelt months and under katabatic drainage winds in winter. Detected sensible turbulent fluxes from nocturnal ventilation processes, although a potentially important ground cooling mechanism, are within our 20 W m−2 uncertainty because nighttime wind speeds are low. Wintertime katabatic wind speeds needed to be scaled to close the SEB, which hints at the limits of parameterisations based on the Monin–Obukhov similarity theory in complex mountain terrain and katabatic drainage winds. The present work contributes to the process understanding of the SEB and climate sensitivity of coarse blocky landforms.

Defining the sanctissimus

This article presents the results of a programme of investigation into vallum enclosures around known or suspected early Christian church sites in eastern Scotland. Survey and keyhole excavation results are reported on for four sites: Abersnithock, Aberdeenshire; Migvie, Aberdeenshire; Glamis, Angus; and Dunkeld, Perth and Kinross. At each site a combination of aerial survey, geophysics and evaluative excavation revealed rectilinear or curvilinear ditched enclosures centring on the position of the church, with radiocarbon dating showing these enclosures are of early medieval date. The significance of the church vallums are discussed, including their role as marking the sacred precincts of the early church and the significance of such large enclosures in the early medieval landscapes of Pictland. In addition to the early medieval results, the geophysical survey at Dunkeld revealed part of old Dunkeld town, which was burnt down and abandoned after the Battle of Dunkeld in 1689.

Green finance, green development and decarbonization of the energy consumption structure.

Energy plays a crucial role in global economic development, but it also contributes significantly to CO2 emissions. China has proposed a "dual-carbon" goal, and a key aspect to achieving this objective is finding effective ways to promote the decarbonization of the energy consumption structure (DECS). Compared with traditional finance, green finance is pivotal in advancing green and low-carbon development. However, the mechanism through which green finance impacts DECS has not been thoroughly explored. This study employs an enhanced weighted multi-dimensional vector angle method, which is more systematic and scientific, to measure DECS. Then, dynamic panel data from 30 provinces in China spanning the years 2003 to 2020 are used. A double fixed-effects model is applied to investigate the impact of green finance on the DECS and identify potential pathways. Results reveal that green finance significantly enhances DECS, primarily by reinforcing green development. The critical impact pathway involves the promotion of green technology innovation and green industry development. Moreover, the enhancing effect of green finance on the DECS is considerably significant in regions with relatively low government spending on science and technology (S&T), and where the focus is not on the "Atmospheric Ten" policy. The measurement of DECS is innovative, and the conclusions derived from it can offer compelling evidence for various social stakeholders. The government has the opportunity to establish a green financial system, supporting green technological innovation and the development of green industries. This approach can accelerate the DECS and work toward achieving the "double carbon" goal at an earlier date.

Effects of early and late sowing on the profitability of cucumber (Cucumis sativus L.) production

Objective: To analyze how early and late sowing can improve the income of cucumber producers in the state of Michoacán, Mexico. Design/Methodology/Approach: Monthly income, production cost, profit, and benefit-cost ratio were calculated in three sowing scenarios: middle, early, and late. Results: In an early sowing scenario, the income and profit of the producers increase by 10.2 and 9.2 million pesos, respectively, compared to the middle sowing scenario. Likewise, in a late sowing scenario, producer income and profits increase by 29.2 and 20.0 million pesos, regarding the middle sowing scenario. Study Limitations/Implications: The negative effects on vegetable prices of temporary excess supply prove the need to plan the surface that will be used for early and late sowing, as well as to create a regulatory body that plans the cucumber sowing area. Findings/Conclusions: Sowing cucumber and other vegetables in early or late dates is recommended, since better production planning will increase the producers’ income and profit.

A Deptford Ship for the House of Savoy? Uncovering the origin of the National Maritime Museum’s Ship Model SLR0436

Model-making has been part of the history of the world as a scaled-down, and often simplified, version of an object. This form of representation has had different functions including validation, creative solution, communication and decoration among others. Models depicting ships are known at an early date from ancient Egypt, although some of those boats had funerary ritual symbolism. More than four millennia later the ship models of the eighteenth century were conceived at a time when naval power was reaching a new chapter offered by technological advancements. Such items, made for shipyards and wealthy patrons, showed details that otherwise would have been missed from the plans and became a physical record of the constructive accomplishment. When other data such as plans are missing, the details from these models are vital to determine the otherwise obscure provenance in the same way as details associated with written or pictorial accounts. The purpose of this paper is to determine the origin of the model SLR0436 stored at the National Maritime Museum’s model collection at its Chatham site. The features of the model will be discussed as well as the merits of the different hypotheses, including the historical context. Finally, it proposes that the most credible provenance, given the evidence, is the Vittorio, a ship built in Deptford in 1716 for the Savoyard navy.

Sustainable practices impact and planting date on yield of sorghum (Sorghum bicolor L. Moench)

Environmental stress affects the yield of sorghum. This impact can be reduced by seed stimulation technique and determining the appropriate planting date. An experiment was conducted in the spring and fall seasons of 2022. Randomized complete block design with split-plot arrangement in four replications was used. Planting dates (spring season: February 15th, March 1st, 15th, April 1st, 15th; fall season: June 15th, July 1st, 15th, August 1st, 15th) were assigned to the main plots. Seed stimulation treatments (banana peel extract 35% + citric acid 100 mg L−1 and soaking in distilled water only) were applied to the subplots. The interaction treatment of soaking with banana peel extract + citric acid and the planting date of April 15th showed superiority in traits of head grain number (1743) and total grain yield (6.135 tons ha−1) during the spring season. Seed stimulation treatment with banana peel extract + citric acid on July 1st planting date outperformed in traits of plant dry weight (398.8 g), head grain number (4582), total grain yield (10.82 tons ha−1), and biological yield (67.8 tons ha−1) during the fall season. It can be concluded that seed stimulation with banana peel extract + citric acid improved yield characteristics. Early planting date in the spring season (February 15th, March 1st, or March 15th) or the delay in the fall season (August 1st or August 15th) resulted in less efficient plant performance. This is closely related to the nature of the climatic conditions accompanying crop growth from planting to harvesting. Also, using of agricultural applications related to the use of natural materials could helping hand sustainable agriculture. It can be recommended to soak seeds with banana peel extract + citric acid and adopt the planting date of April 15th for the spring season and July 1st for the fall season to enhance grain yield.

Studying the cumulative vigor response index of morpho-physiological, quality, and yield-related traits of wheat cultivars using planting dates

Wheat (Triticum aestivum L) is one of the major staple food crops consumed globally. Nonetheless, the cultivation of wheat is influenced by various environmental factors, with the planting date being significantly impacted by the effects of climate change. Addressing these changes could involve evaluating wheat genotypes to identify appropriate planting dates. A phenotypic screening experiment was conducted in the field crop station of Agriculture College of Tikrit University to determine the suitable planting time for wheat cultivars under local environmental conditions during 2022-23. Several morpho-physiological, quality, and yield traits were measured. Factorial experiment using spilt plot through randomized completely block design (RCBD). was used with three replications. The five planting dates (5-10, 25-10, 15-11, 5-12, and 25-12) were considered as the main plot, and the eight wheat cultivars (Ipaa99, Al-Rasheed, Al-Baraka, Sham6, Tammuz2, Al-Hashimiya, Al-Noor, and Al-Adnanieh) as sub-main plot. Data were used to calculate the Individual, Cumulative, and Total Vigor Response Indices (IRI, CRI & TRI). Cultivars were classified into different categories using total cumulative early or late planting date vigor response index values (TRI-e) or (TRI-l) and standard deviation (SD). The (TRI-e) values ranged from 36.07 (sensitive) for the cultivar Al-Baraka to 39.13 (tolerant) for the cultivar Al-Hashimiya. However, the (TRI-l) values ranged from 36.59 (sensitive) for the cultivar Al-Noor to 39.52 (tolerant) for the cultivar Al-Hashimiya. The correlation coefficient (r2) between the (TRI-e) and cumulative very early/early planting date vigor response index was positively correlated (r2 = 0.70 for very early planting date (5-Oct) and r2 = 0.60 for early planting date (25-Oct). Furthermore, 76% of the total variation in the (TRI-l) was explained by the cumulative very late planting date vigor response index (CRI-vl) while just 49% of the total variation was explained by the cumulative late planting date vigor response index (CRI-l). Based on those results, wheat producers could select either tolerant cultivars for early planting or tolerant cultivars for late planting to maximize wheat production in their specific growing environments including planting dates.

Bплив ранньовесняних строків сівби насіння ромашки лікарської на польову схожість та виживання рослин в умовах правобережного лісостепу України

An important place in the effective technology of growing medicinal chamomile (Matricaria recutita L.) is occupied by the early spring sowing period. Therefore, they provide a dense emergence of seeds, as evidenced by many conducted scientific studies in the field of plant breeding. The article presents the results of experimental research on the effect of early spring sowing dates of medicinal chamomile on field seed germination and plant survival. It was established that medicinal chamomile plants depended on weather and climatic conditions, sufficient amount of moisture in the soil, soil crust, which as a result led to variation in the passage of growth and development phases, and therefore, a question arose in the study of agrotechnical techniques aimed at the productivity of medicinal raw materials. The cultivation of tetraploid of medicinal chamomile variety Perlyna Lisostepu and Zloty Lan in the conditions of the Right-Bank Forest-Steppe of Ukraine during the period of research (2018-2023) in the early spring sowing period was studied. It was established that the investigated varieties of medicinal chamomile had the highest field germination of seeds due to the content of productive moisture. The highest field seed germination rates of 74.16% were recorded during the early spring (15-18.04) sowing period of the Perlyna Lisostepu variety, and the Zloty Lan variety was 72.68%, respectively. According to six-year research data, the highest field seed germination of 68.00% on the control variant (1-3.04) according to the sowing dates was noted in the Perlyna Lisostepu variety, and the lowest 67.00% – in the Zloty Lan variety. The maximum rate of plant survival at the end of the growing season was 88.96%, which was obtained in the variant of the early spring (15-18.04) sowing period of the Perlyna Lisostepu variety, the minimum rate was 69.15% in the control (1-3.04) of the Zloty Lan variety. The germination rate on average over six years exceeded the control by 6.14%, and the survival of chamomile plants on average over the years of research exceeded the control option by 1.5%. The difference in factors was insignificant (2-3%)

Double feature: First genetic evidence of a mother-daughter double burial in Roman period Austria

A human double burial combined with a horse interment, discovered in 2004 in the eastern cemetery of the Roman town of Ovilava (today Wels/AUT), has been the subject of a comprehensive interdisciplinary study. This burial was remarkable for two reasons: firstly, the arrangement of the two individuals, with individual 1 having an arm around individual 2, and secondly, the presence of equine skeletal remains in the same burial pit directly below the human remains. Based on this finding, an initial assessment suggested a mixed-sex pair buried together with a horse. The horse burial was interpreted as an indicator of an early medieval date. The position of the two human skeletons suggested that a male and female individual had been buried together. A thorough examination of both the human and horse skeletons disproved these initial interpretations. Radiocarbon dating of the human and horse skeletons dated them to the Roman period. In addition, ancient DNA (aDNA) analysis of the human remains corrected the earlier sex assumption, revealing that the individuals were two biological females who were first-degree relatives. The age difference of 15 to 25 years between the two suggests a probable mother-daughter relationship. Thus, the application of scientific methods confirmed a rare, combined human-horse burial from Roman antiquity and established the first genetically documented mother-daughter burial from this period in present-day Austria.

New Evidence Against an Early Date for Hamlet

New Evidence Against an Early Date for Hamlet

On some Features of Funerary Assemblage of the Egyptian Priestess Nesmut

The subject of this paper is the analysis of funerary assemblage of Nesmut, the Egyptian priestess of the 21st Dynasty (her titles are “Mistress of the House, Chantress of Amun, king of the gods”). The burial of Nesmut was discovered in 1891 in the so-called “Second Cache” at Deir al-Bahri, also known as Bāb el-Gusūs (set no. A.48). Inventory that was discovered on the mummy: leather mummy braces, three “napkins”, linen gloves, shale heart scarab, and wax images of the sons of Horus. Inventory that was found near or inside of the coffin: two shabti-boxes, shabtis. Nesmut’s mummy cover is located in the Museum of Antiquities in Cairo (Cairo CG 6007). Her coffin is currently stored in the Odesa Archaeological Museum (OAM) of the National Academy of Sciences of Ukraine (inv. no. 71695). It was part of the so-called Lot VI presented to Russian Empire by Egyptian government in 1893. In 1895, the coffin of Nesmut was sent from Odesa to the Archaeological Museum of St. Volodymyr Kyiv University. In 1959 the coffin of Nesmut was among other objects that were transferred from the State Republican Historical Museum in Kyiv to the OAM. The lid of the coffin with inv. no. OAM 71695 differs in design style from the trunk and has an earlier dating. Structurally, the lid has retained traces of technological processing and fitting the trunk of the later coffin of its namesake. Accordingly, there were two Nesmuts, whose funerary objects were discovered in Bāb el-Gusūs. The burial of Nesmut (II) corresponds to the set no. A.48 by Daressy and it is linked with the coffin trunk no. OAM 71695. Separate objects from Nesmut’s (I) grave goods were adapted for later burials: the lid of her inner coffin was used for the Odesa coffin of Nesmut (II), and the lid of the outer coffin might have been adapted for an anonymous burial from Bāb el-Gusūs set no. A.54 (Swiss lot IX, Neuchâtel, Musée d’Ethnographie, inv. no. Eg. 184) on which the name “Nesmut” preserved in one segment of the lid. The burial of Nesmut was also equipped with two different types of shabtis. It is possible that like the lid of the coffin, part of the shabtis was “usurped” by Nesmut (II) and previously belonged to the burial of her namesake and probably relative, Nesmut (I). It is quite probable, that they were reused and adopted for the burial of new owner together with the shabti-box, since the two of them were found in the set no. A.48. This may prove that during the 21st Dynasty, not only large objects, but also small items of grave goods could be reused.

Drought risk assessment for early maize growth in Northeast China based on a reconstructed phenological dataset

AbstractDrought is one of the meteorological disasters to which maize is most vulnerable during its seedling stage in Northeast China. The absence of phenological data impedes the precise evaluation of the likelihood of drought during this phase. In response to these issues, this study develops a phenology model and reconstructing the data. Furthermore, it effectively assessed drought risk at the site scale by utilizing drought indicators. Using reconstructed phenological data from 217 sites from 1981 to 2015, we analysed the duration and trends of each phenological period and assessed the spatial and temporal distribution of drought frequency at each growth stage. The study demonstrated that the average date ranges for the sowing, emergence, three‐leaf, and seven‐leaf stages annually were 115–138 days, 130–151 days, 135–160 days, and 150–180 days, respectively. Additionally, there was a significant trend towards earlier dates in all phenological stages. Our research reveals notable fluctuations in drought frequency during various growth stages of early maize in Northeast China. Particularly, the period from the three‐leaf to the seven‐leaf stages emerges as the most drought‐prone, while the initial emergence to three‐leaf stage also shows considerable vulnerability. On average, the frequency of drought events during the critical three‐ to seven‐leaf stage stands at 35%. This average is surpassed in regions like Heilongjiang, northwest Jilin, northern Inner Mongolia, and southwest Liaoning, indicating a heightened risk in these areas. The early maize growth stage drought types are mainly light and moderate drought, with the three‐leaf to seven‐leaf stage, and Heilongjiang and Inner Mongolia, as the key stages and regions of concern, respectively. Identifying the principal types of drought and their occurrence in distinct regions and growth stages is pivotal for averting and reducing disasters.

Prehistoric and Early Medieval Settlement Features at Ravelrig Road and Newmills Road, Balerno, City of Edinburgh

Evaluation and excavation works in advance of housing development at two sites on Ravelrig Road and Newmills Road, Balerno, City of Edinburgh, revealed significant archaeological features evidencing multi-phase settlement. At Ravelrig Road, two groups of pits were dated to the Early and Middle to Late Neolithic periods with a cluster of Copper Age and Early Bronze Age features that included two possible storage features. At Newmills Road, alongside limited evidence for late prehistoric occupation in the form of pits dating to the last centuries BC and the first centuries AD, the most significant remains were of early medieval date, including a ring-groove representing a putative roundhouse and other features, including a hearth and linear boundary features, generally placed between the 7th and 9th centuries AD according to radiocarbon dating.

An Early Iron Age Roundhouse at Gartness Road, Drymen, Stirling

An archaeological excavation at Gartness Road Drymen, undertaken by Headland Archaeology (UK) Ltd in 2020, revealed the remains of an early Iron Age roundhouse and a small collection of pits. The remains exhibited a high level of truncation, which obscured the potentially complex nature of the structure. The site was located on the south-eastern edge of Loch Lomond and the Trossachs National Park, an area which sits on the traditional highland to lowland boundary. This unique location and early date for the structure provided an opportunity to explore construction styles, potentially contemporary activity and its relationship to surrounding structures.

Kombinasi Algoritma Priority Scheduling dan Earliest Due Date untuk Sistem Penjadwalan Slitting Produk Berbasis Web

Production scheduling is one of the most critical components of production management that can impact efficiency and resource utilization. This research focuses on the development of a web-based production scheduling system that integrates two algorithms, Earliest Due Date (EDD) and Priority Scheduling. This research includes the analysis, design, implementation and testing of a those two algorithms in a web-based application for production management. The result of this research will be analyzed through the results of how both algorithms affects lateness and tardiness. The research findings indicate that the application can effectively manage Work Orders. The application can generate an optimal schedule when conditions arise where some tasks have higher priority than others by combining both algorithms. The system can identify potentially late tasks by calculating the tardiness of the given jobs. And from the analysis results, the application can generate an efficient production schedule with an on-time accuracy rate of 74%, and the average delay for each job is 0.95 hours.