Dysuria In Women Research Articles

Persistent dysuria in women: etiological diagnostics and treatment

INTRODUCTION: Dysuria is a painful urination combined with its frequency and/or difficulty. Dysuria is observed in many urological diseases and is one of the most common reasons for treatment for urological cause.
 AIM: The aim of the study is to identify the etiological factors of dysuria in women and to evaluate a personalized approach to their treatment.
 MATERIALS AND METHODS: We analyzed the data of 368 women with chronical cystitis. The inclusion criteria for the study were the presence of dysuria (painful and frequent urination more than 8 times a day with or without difficulty), the prescription of urination disorders over one year old and age 18 and over. All patients underwent a comprehensive urological examination to identify the causes of urinary disorders.
 RESULTS: The Bacterial cystitis was confirmed only in 78 (21.2%) patients among all 368 women. In the remaining 290 (78.8%) patients, the causes of persistent dysuria were other diseases: bladder leukoplakia in 154 (41.8%), bladder pain syndrome/interstitial cystitis in 38 (10.3%), viral cystitis in 34 (9.3%), paraurethral formations in 29 (7.9%), neurogenic urinary dysfunction bladder in 25 (6.8%), urethral pain syndrome in 5 (1.4%) patients. Dysuria was also caused by postradiation cystitis (2 patients), secondary stones in the urinary bladder (2 patients), and one patient had extragenital endometriosis.
 CONCLUSIONS: The variety of reasons for the development of persistent dysuria in women requires careful examination of patients. Treatment should be carried out only after accurate verification of the diagnosis.

The role of human paillomavirus in the development of squamous urothelial metaplasia

Squamous metaplasia of the vesical triangle urothelium often accompanies chronic cystitis in women with dysuric simptoms. There is no generally accepted diagnosis and treatment of this condition. The etiological factor is unknown. Thus it is very important to determine the etiological factor in the development of dysuria in women with squamous metaplasia. 50 women with the signs of urothelial squamous metaplasia and persistent or recurrent dysuria for more than 6 months participated in our study. All patients underwent cystoscopy, biopsy was taken from the site suspicious for squamous metaplasia. Urethra scraping was also performed. The samples were tested for the DNA of the human papillomavirus (HPV). HPV was found in 41 patients (82%). Consequently, it can be supposed that the human papillomavirus can be the cause of dysuria in women with squamous metaplasia of the vesical triangle.

Trimethoprim reduced dysuria in women with symptoms of urinary tract infection but negative urine dipstick test results

Trimethoprim reduced dysuria in women with symptoms of urinary tract infection but negative urine dipstick test results

Trimethoprim reduced dysuria in women with symptoms of urinary tract infection but negative urine dipstick test results

Trimethoprim reduced dysuria in women with symptoms of urinary tract infection but negative urine dipstick test results

Trimethoprim reduced dysuria in women with symptoms of urinary tract infection but negative urine dipstick test results

Trimethoprim reduced dysuria in women with symptoms of urinary tract infection but negative urine dipstick test results

Dysuria in Women--Who Needs a Pelvic Examination?

Dysuria in Women--Who Needs a Pelvic Examination?

Infection and dysuria in women

Infection and dysuria in women

Causes of Frequency and Dysuria in Women

Bacteria in excess of 10(4) colony-forming units per ml (CFU/ml), were isolated from voided urine specimens from 127 (79%) of 160 women, 15-45 years of age, consulting in general practice due to frequency and dysuria. Escherichia coli was the species most frequently isolated, followed by Staphylococcus saprophyticus. Chlamydia trachomatis was isolated from 8 (5%) patients, in 6 of whom greater than 10(4) CFU/ml urine were isolated. A 2-fold titre increase in micro-immunofluorescence antibodies to C. trachomatis was demonstrated in 8 cases, the organism itself being isolated in 1 case only. No viruses were isolated in any of 18 women with negative urine cultures. Proteinuria and/or haematuria was found more frequently in patients with S. saprophyticus than in patients with gram-negative rods. Tests for nitrite indicated bacteriuria in only 58% of the patients with greater than 10(4) CFU/ml urine, which can be partly explained by the fact that S. saprophyticus only occasionally reduces nitrate. Cocci were noted in urine sediment in 75% of patients in whom S. saprophyticus was isolated.

Current therapy of urinary tract infections and pyelonephritis.

U RINARY tract infections (UTIs) are common problems in both inpatient and outpatient settings. Despite the frequency with which these infections are encountered and the volume of literature concerning them, controversy still exists about their optimal treatment. Recent studies have helped to delineate the etiologies of acute dysuria in women, one of the most common presentations of UTIs, and have begun to compare different regimens of treatment. It is now apparent that Stuphylococcus saprophyticus is a common cause of UTIs in young women. Nosocomial UTIs remain a major cause of morbidity and mortality despite vigorous attempts to prevent them. New antimicrobial agents are available for treatment of UTIs; some may eventually replace nephrotoxic aminoglycosides for treatment of severe or complicated infections. Diagnostic tests and antimicrobits are not inexpensive; in these days of cost containment, the clinician is challenged by the need to find the most cost-effective means to treat and prevent UTIs. The goals of treatment of UTIs are to provide relief of symptoms, eradicate the focus of infection, prevent recurrences due to either relapse of the same infection or acquisition of a new infection, and to prevent renal damage. Unless obstruction of urine flow caused by anatomic variant, stone, or other problem is present, UT1 in adults rarely causes renal parenchymal damage sufficient to lead to end-stage renal disease. Success in treatment of UT1 correlates best with the susceptibility of the causative microorganism to concentrations of antimicrobics, which can be attained in urine rather than the concentration attainable in blood. In theory, use of bacteriocidal drugs would be preferable, but there is no real evidence that bacteriocidal drugs are superior to bacteriostatic agents. Because response to therapy is dependent on a number of factors including the site of infection, presence of complicating factors such as neurogenie bladder, stones, or need for indwelling catheters, there is no single best treatment plan. Rather, the costs, side effects, inconvenience to the patient, and the likelihood that a particular treatment will be effective must be evaluated for each patient. This article discusses some of the recent developments in the understanding and therapy of the major categories of UTIs that occur in adults: acute dysuria of women, pyelonephritis, prostatitis, and asymptomatic bacteriuria in special situations. For more comprehensive reviews of UTIs, the reader is referred to several recent publications.’ 4

Acute dysuria in women.

AS many as a quarter of adult women may experience an episode of acute dysuria each year.1 Dysuria is one of the most common clinical problems seen by clinicians in the developed Western nations,2 3 4 accounting for over 3 million office visits per year in the United States.4 Recent studies suggest that we need to alter traditional approaches to the care of women who have the acute onset of dysuria but do not have symptoms or signs suggesting acute pyelonephritis. The conventional view has held that (1) such patients have bacterial cystitis, (2) the responsible microorganisms are almost always the gram-negative . . .

A Strategy for Efficient Diagnosis and Treatment of Dysuria in Women in the Military Setting

A Strategy for Efficient Diagnosis and Treatment of Dysuria in Women in the Military Setting

Urethritis and Pure Urinary Tract Infection (UTI)

To the Editor.— Komaroff et al should be commended on their interesting and informative article in theArchivesregarding the evaluation of dysuria in women with and without vaginitis (138:1069-1073, 1978). However, several problems in their analysis of their results should be noted. In Table 2, urethritis is listed as a subcategory of pure UTI, whereas the authors imply that this diagnostic entity refers to patients with lower urinary tract symptoms, normal findings on pelvic examination, and insignificant bacterial growth on urine culture, a clinical situation that is often termed the syndrome. As noted in other studies, 1 the urethral syndrome accounts for approximately one third to one half (in this case 40 of 98, or 41%) of all cases of dysuria in the absence of marked vaginitis or gonorrhea. As patients with the urethral syndrome generally do not respond to antibiotics, 2 grouping them with bacteriuric pure UTIs

Frequency and dysuria in women

Frequency and dysuria in women

Frequency and dysuria in women

Frequency and dysuria in women

Frequency and dysuria in women.

Frequency and dysuria in women.

Frequency and dysuria in women

Frequency and dysuria in women

Dysuria in Women

Dysuria in Women

Dysuria in women.

Dysuria in women.

Clinical significance of dysuria in women.

During a community survey 22% of women were found to have had dysuria in the previous year and half had had dysuria at some time in their lives. Various measurements were made in a random sample of 282 of these women. The means and the variances of the systolic and diastolic blood pressures in women with a past history of dysuria tended to be higher than in women who gave no such history. There were no significant differences in the means of plasma urea, plasma creatinine, and renal concentrating power between women with and without a previous history of dysuria, but a significant impairment of renal concentrating power was found in an additional group of 30 women who dated the onset of their dysuria to childhood.These findings suggest that urinary tract infection in adult women does not usually lead to progressive impairment of kidney function, whereas infection in childhood is more often associated with kidney damage.