We compute the cross section for leptoproduction of the real photon off the nucleon, which is sensitive to the deeply virtual Compton scattering amplitude with power accuracy. Our considerations go beyond the leading twist and involve the complete analysis in the twist-three approximation. We discuss consequences of the target and lepton beam polarizations for accessing the generalized parton distributions from experimental measurements of the azimuthal angular dependence of the final state photon or nucleon. We introduce several sets of asymmetries, defined as Fourier moments with respect to the azimuthal angle, which allow for a clear separation of the twist-two and -three sectors. Relying on a simple ansatz for the generalized parton distributions, we give quantitative estimates for azimuthal and spin asymmetries, discuss the uncertainties of these predictions brought in by radiative corrections, and compare them with experimental data as well as other theoretical expectations. Furthermore, we derive a general parametrization of the DVCS amplitudes in the region of small Bjorken variable.