We present a multiwavelength spectral study of NGC 4151 based on five epochs of simultaneous AstroSat observations in the near-ultraviolet (NUV) to hard X-ray band (∼0.005–80 keV) during 2017–2018. We derived the intrinsic accretion disk continuum after correcting for internal and Galactic extinction, contributions from broad- and narrow-line regions, and emission from the host galaxy. We found a bluer continuum at brighter UV flux, possibly due to variations in the accretion disk continuum or the UV reddening. We estimated the intrinsic reddening, E(B − V) ∼ 0.4, using high-resolution Hubble Space Telescope (HST)/STIS spectrum acquired in 2000 March. We used thermal Comptonization, neutral and ionized absorption, and X-ray reflection to model the X-ray spectra. We obtained the X-ray absorbing neutral column varying between N H ∼1.2 and 3.4 × 1023 cm−2, which are ∼100 times larger than that estimated from UV extinction, assuming the Galactic dust-to-gas ratio. To reconcile this discrepancy, we propose two plausible configurations of the obscurer: (a) a two-zone obscurer consisting of dust-free and dusty regions, divided by the sublimation radius, or (b) a two-phase obscurer consisting of clumpy, dense clouds embedded in a low-density medium, resulting in a scenario where a few dense clouds obscure the compact X-ray source substantially, while the bulk of UV emission arising from the extended accretion disk passes through the low-density medium. Furthermore, we find a positive correlation between the X-ray absorption column and NUV − far-UV color and UV flux, indicative of enhanced winds possibly driven by the “bluer-when-brighter” UV continuum.