Duration Of COVID-19 Research Articles

COVID-19 was associated with the complications after allogeneic hematopoietic stem cell transplantation

We aimed to identify the severity and duration of COVID-19 infection on complications after allo-HSCT. Enrolled 179 hospitalized patients with COVID-19 were categorized into long-term infection (> 18 days, n = 90) or short-term infection group (≤ 18 days, n = 89) according to the median duration of COVID-19. The severity of COVID-19 was categorized as asymptomatic infection, mild, moderate, severe, and critical illness according to guidelines of National Institutes of Health. Particularly, severe illness and critical illness were classified as serious infection. Asymptomatic infection, mild illness and moderate illness were classified as non-serious infection. The 150-day probabilities of poor graft function (PGF), cytomegalovirus (CMV) pneumonia and non-relapse mortality (NRM) were significantly higher in long-term infection group. The 150-day probabilities of CMV pneumonia and NRM after COVID-19 were higher in serious infection group. The 150-day probabilities of overall survival (OS) was significantly lower in long-term and serious infection group. In multivariable analysis, the severity of COVID-19 was associated with NRM and OS, and the duration of COVID-19 was associated with PGF. In summary, our data reported that the severity and duration of COVID-19 were associated with several complications and contribute to poor outcomes after allo-HSCT.

Psychopharmacotherapy factor in the variants of COVID-19 course in psychiatric inpatients

The aim of this study is to examine the relationship between the severity and duration criteria of COVID-19 and the psychopharmacotherapy administered to patients in within a psychiatric hospital.Materials and Methods. We analyzed 169 case histories involving completed clinical cases of COVID-19 treatment in a specialized infectious psychiatric department in St. Petersburg, covering the period from May 2020 to January 2021. Correlation, dispersion, and regression analyses were employed to evaluate severe and mild COVID-19 progression indicators, as well as the duration of persistent SARS-CoV-2 viral shedding. We assessed the clinical and laboratory parameters in patients, along with the psychopharmacotherapy administered, including antidepressants, antipsychotics, and acid sphingomyelinase inhibitors (FIASMA-active drugs).Results. Cardiovascular diseases emerged as a predictor of severe COVID-19 when combined with an increasing platelet-to-lymphocyte ratio (PLR), increasing the risk of severe course by over two-fold. The use of any psychotropic agents was associated with a 0.9% increase in the risk of severe course of COVID-19 for each unit increase in the systemic inflammation index PLR, specifically in patients with intellectual disability (ICD-10 codes F70-79), when compared to patients with schizophrenia (ICD-10 codes F20-29). High PLR values and the use of FIASMA-active drugs were associated with prolonged COVID-19 duration, while antidepressant therapy and elevated C-reactive protein levels were associated with a reduced predicted duration of viral shedding in 13.8% of variance. Additional consideration of the nosology of psychiatric disorders in the regression model increased the proportion of explained variance to 22.8%.Conclusion. Consideration should be given to thymoanaleptic therapy for individuals with psychiatric disorders during periods of increased disease incidence leading up to potential SARS-CoV-2 infection, as it may serve as a protective factor against COVID-19. Furthermore, there is no evidence to suggest adverse effects of antipsychotics on the severity and duration of COVID-19. Further research is required to investigate the effects of FIASMA-active psychopharmacological agents within nosologically homogeneous groups.

Measurement and Influencing Factors of Economic Resilience over a Long Duration of COVID-19: A Case Study of the Yangtze River Delta, China

The COVID-19 pandemic put forward a new test for an economic resilience study. Its long-term and diffusive spatiotemporal characteristics suggest that we need to pay attention to the resilience and spatial heterogeneity of cities over a longer period. This paper applied SARIMA and the performance curve to measure the economic resilience of each city under the pandemic, and explored its influencing factors and spatial heterogeneity using a geodetector and geographically weighted regression model. The results show that: (1) From 2020 to 2022, the economic resilience in the Yangtze River Delta presented a downward to upward to slightly downward trend. High-resilience cities were concentrated in southern Jiangsu, while vulnerable cities were primarily located in western Anhui. The performance of regional core cities was not as strong as in previous research focusing on long-term economic resilience. (2) Fixed-asset investment, related variety, labor supply level, foreign trade dependence, and innovation level were the main influencing factors, on average. The effects of these factors had spatial heterogeneity related to the regional endowment and development quality. The findings suggest that the specificity of public health risks and the lack of coping experience may lead to a general failure of economic resilience. Identifying key factors and current weaknesses in each region can make resilience improvement strategies more targeted and effective.

Leadership Styles and Employee Performance during COVID-19: A Case Study of Pakistani Organizations

The COVID-19 pandemic has delivered unparalleled challenges to global organizations, impacting leadership patterns and employee overall performance. The research efforts summarized the management patterns and employee performance inside the context of Pakistani companies during the pandemic. It explores the effect of transformational, transactional, autocratic, and democratic management styles on workers' overall performance, job pleasure, and motivation. The management demanding situations examined emerged during the duration of COVID-19 and the adaptive practices hired by way of leaders. The findings offer potential insights for organizational leaders and practitioners, highlighting the dynamic and responsive management technique in times of crisis. In this case study, three distinguished Pakistani companies (Acme Pharmaceuticals, Green Tech Solutions, and Global Logistics) were tested. These agencies were decided to symbolize a diverse variety of industries and organizational systems, supplying a comprehensive attitude on leadership patterns and employee overall performance throughout the COVID-19 pandemic.

Morphological prediction of lethal outcomes in the evaluation of lung tissue structural changes in patients on respiratory support with СOVID-19: Ukrainian experience.

The impact of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) on lung tissue in patients on respiratory support is of significant scientific interest in predicting mortality. This study aimed to analyze post-mortem histological changes in the lung tissue of COVID-19 patients on respiratory support using vital radiology semiotics. A total of 41 autopsies were performed on patients who died of SARS-CoV-2 and had confirmed COVID-19 by polymerase chain reaction (PCR) and radiological evidence of lung tissue consolidation and ground glass opacity. The results showed that the duration of COVID-19 in patients on respiratory support was significantly associated with the development of all stages of diffuse alveolar damage, acute fibrous organizing pneumonia, pulmonary capillary congestion, fibrin thrombi, perivascular inflammation, alveolar hemorrhage, proliferating interstitial fibroblasts, and pulmonary embolism. The prediction model for lethal outcomes based on the duration of total respiratory support had a sensitivity of 68.3% and a specificity of 87.5%. In conclusion, for COVID-19 patients on long-term respiratory support with radiological signs of ground glass opacity and lung consolidation, post-mortem morphological features included various stages of diffuse alveolar lung damage, pulmonary capillary congestion, fibrin clots, and perivascular inflammation.

An Important Play Role of Polymer in Daily Life and Duration of Covid19

Abstract: In this article we are focused on specially application of polymers and what hazards effects will come in future . Because at present time polymer application day by day used in multifunctional work. Here we want to discuss type of polymer. Synthetic polymers having wide applications like as a electronic equipments ,aerospace application, Light equipment , Cardiac heart valves, Polymer base mesh used in prevent of hernia in human body, synthetic polymer rayon useful in textiles industries. Synthetic polymers are vast used in medical sectors ,like as drug delivery, many packing are easily transported from one palace to other palace self-healing, and molecular-recognition materials. Many researchers have synthesized gel materials by designing their molecular and macroscopic structure as well as the constituent materials from the perspective of organic chemistry, physical chemistry, and biochemistry, among others. In addition, the fact that pharmacy, biomedicine, molecular biology, biochemistry, and biophysics are the fields that polymers and polymer chemistry play a significant role in the development of their new areas. It is obvious why the study of giant molecules is one of the most attended and the fastest growing fields of science. Therefore, it seems that polymer is not a specialized interdisciplinary or branch of chemistry. Here I have mention one of the polymers made by me and focused on application of polymers.

Acute COVID-19 Syndrome Predicts Severe Long COVID-19: An Observational Study

IntroductionTissue damage, chronic dysfunction, and symptoms that last more than 12 weeks are hallmarks of long-term chronic opportunistic viral infection (COVID-19), and the disease may have a permanent, relapsing/remitting, or gradually improving course. This study aimed to determine the risk factors of severe long COVID-19.MethodsIn October 2021, primary care clinics enrolled consenting 18- to 89-year-olds to complete an online questionnaire on self-diagnosis, clinician diagnosis, testing, symptom presence, and duration of COVID-19. Long COVID-19 was identified if symptoms were beyond 12 weeks. Patients with long-lasting COVID-19 symptoms were assessed using multivariable regression to identify potential predictors of severe long COVID-19.ResultsOf the 220 respondents, 108 (49%) patients were self- or clinician-diagnosed with COVID-19 or had a confirmed positive laboratory test result. Patients aged >45 years and with at least 15 COVID-19 symptoms were 5.55 and 6.02 times, respectively, more likely to acquire severe long COVID-19. Most patients with severe and moderate post-acute COVID-19 syndrome had no relevant comorbidities (p=0.0402; odds ratio [OR]=0.4; 95% confidence interval [CI]=0.18-0.98). Obesity was a significant predictor (p=0.0307; OR=6.2; 95% CI=1.1-33.2).ConclusionThe simultaneous presence of 15 or more COVID-19 symptoms, age >45 years, and obesity were related to a higher probability of severe long COVID-19.

An Overview of Clinical Features, and Medical Access Among Patients with Post-Acute COVID-19 Syndromes: Analysis of a Nationwide Survey in Korea

Background: The objective of this study was to identify the clinical features of patients who recovered from COVID-19, and to determine their unmet medical needs and quality of life.Methods: A cross-sectional national survey was conducted in Korea in June 2022, targeting patients with at least four weeks of symptoms of COVID-19. The questionnaire survey had 37 items across: basic characteristics, acute COVID-19 and post-acute COVID-19 syndrome (long COVID) symptoms, access to medical facilities for long COVID, unmet medical needs, long COVID support system, and quality of life.Results: Among 1,430 responses, 745 (52.1%) respondents had experienced long COVID. The most common symptoms were ear, nose, and throat complications (n = 461, 61.9%), followed by weakness and fatigue (n = 393, 52.8%). Amongst the 745 respondents who experienced long COVID, 337 (45.2%) had visited a medical institution, of which, 84.9% had visited a clinic or hospital for treatment. Korean medicine clinics and hospitals had the highest satisfaction rates (43.4%). There were 242 respondents (32.5%) who reported unmet medical needs for their long COVID. Symptom severity and duration of COVID-19 were risk factors for unmet medical needs. Quality of life was low in those patients with long COVID and unmet medical needs, and decreased further with increased severity and longer duration of symptoms.Conclusion: Studies on the effects of Korean medicine treatment of long COVID, and establishing a system providing sufficient treatment for patients with long COVID are needed. These findings could be used by clinicians, researchers, and COVID-19-related policymakers.

POST-COVID AND ITS GASTROINTESTINAL MANIFESTATIONS

This article provides a review of the literature on such a relevant topic in the epidemiological situation, on the impact of COVID-19 on the digestive organs and post-covid manifestations from the gastrointestinal tract. A review of more than 15 international literature sources and metadata is presented, reliable factors about post-COVID manifestations are given. Depending on the course and duration of COVID-19, definitions of the diagnosis are presented. It also presents the multi-system nature of Post-COVID. The main purpose of this article is to review the literature and metadata from sources to assess the impact of COVID-19 on the gastrointestinal tract and the nature of post-COVID gastrointestinal manifestations. The COVID-19 pandemic has gripped millions of people around the world, leaving a global burden. Therefore, it is important to continue studying the theoretical and clinical foundations of the disease, both in the main period of the disease, and multiple organ manifestations of COVID-19, as systemic pathophysiological consequences. The main conclusion of this article can reasonably be said about the negative impact of SARS-CoV-2 on the gastrointestinal tract in the acute period, as well as the long-term effects of the virus on the gastrointestinal tract. The digestive organs, as well as the respiratory organs, are the entrance gates of the virus.

Self-perceived dysphagia in non-invasively ventilated COVID-19 patients

PurposeCOVID-19 is known to present with a wide range of clinical symptoms. COVID-19-related dysphagia has been frequently investigated in patients who were critically ill and mechanically ventilated, but not in those with less severe presentations. This study aims to identify the frequency, characteristics, and severity of self-perceived oropharyngeal dysphagia in non-intubated COVID-19 patients.MethodsIn this cross-sectional study, data were collected from patients using a self-administered questionnaire that included the Eating Assessment Tool (EAT-10).ResultsThe study included 359 participants with a median age of 34 (range: 18–65) years. Self-perceived dysphagia (EAT-10 total score > 2) was identified in 64.62%, and their median EAT-10 total score was 13 (range 3–40). The most prevalent symptoms were painful swallowing, affected pleasure of eating, stressful swallowing, and coughing while eating. Age, gender, and hospitalization were not statistically significantly associated with the presence of dysphagia, while re-infection, duration, and severity of COVID-19 diagnosis were. The EAT-10 total score was higher in moderate and severe COVID-19 cases as compared to mild cases, and showed a statistically significant inverse correlation with the duration of COVID-19 (r = − 0.267).ConclusionSelf-perceived dysphagia was prevalent in non-intubated COVID-19 patients. Its severity was related to that of COVID-19 and its duration.

Evaluate the Post-Brexit Trade Performance under the Comparison Analysis between Britain and France in the Context of COVID-19

With the result of the UK referendum indicating that the UK agrees to leave the EU, the trade situation has changed a lot, especially in the duration of Covid-19. This paper employs the export and import data of France and Britain between 2019 to 2021. The results show that both France and Britain suffer a deep decline in trade value in 2020 due to the disadvantages brought by the outbreak of Covid-19. Also, the trade value recovers in 2021. his paper concluded that Britain lose more than France to its’ loss of EU membership, including the attractiveness reduction of foreign direct investment (FDI), raising the cost of trade transportation and fewer voices in the European Court of Justice.

Review of human interferons and the potential of their use in the complex therapy of a new coronavirus infection COVID-19

Interferons (IFNs) were first discovered over 60 years ago in a classic experiment by Isaacs and Lindenman showing that type I IFNs have antiviral activity. IFNs are widely used in the treatment of multiple sclerosis, viral hepatitis B and C, and some forms of cancer. Preliminary clinical data support the efficacy of type I IFN against potential pandemic viruses such as Ebola and SARS. Nevertheless, more effective and specific drugs have found their place in the treatment of such diseases. As the COVID-19 (SARS-CoV-2) pandemic is evolving, type I IFN is being re-discussed as one of the main pathogenic drugs, and initial clinical trials have shown promising results in reducing the severity and duration of COVID-19. Although SARS-CoV-2 inhibits the production of IFN-β and prevents a full innate immune response to this virus, it is sensitive to the antiviral activity of externally administered type I IFN. The review presents current data on the classification and mechanisms of action of IFN. Possible options for the optimal use of IFN in the fight against COVID-19 are discussed.

Determination of the Prevalence of Postcovid Syndrome and Assessment of the Effectiveness of the Drug Cortexin in the Treatment of Neurological Disorders in Patients with Postcovid Syndrome. Results of the CORTEX Multicenter Clinical and Epidemiological Observational Program.

Objectives. To study the prevalence and clinical manifestations of postcovid syndrome (PCS) in out-patients and to assess the efficacy of treatment with the drug Cortexin at doses of 10 and 20 mg i.m. for 10 days. Materials and methods. A total of 979 patients with PCS from regions of the Russian Federation, Azerbaijan, Kyrgyzstan, and Kazakhstan were studied; mean age was 54.6 ± 4.5 years; duration of COVID-19 was from one month upwards. Investigations involved three visits. The first was on the day of consultation (assessment of complaints, analysis of scale indicators, prescription of drug Cortexin at a dose of 10 or 20 mg i.m. for 10 days). The second visit (telephone consultation) was on day 10–14. The third visit was on day 30 of out-patient treatment. Assessment of patients’ status used an asthenia assessment scale (MFI-20), a brief mental state assessment scale (MMSE), the Schulte test, and the Subjective Treatment Quality Assessment Scale. Results. The proportion of patients with PCS was up to 30% of all neurological admissions. The commonest manifestations were: fatigue, general weakness, decreased memory and concentration of attention, vertigo, sleep impairment, irritability, and aggression; less frequent were breathlessness, pain, increased sweating, anosmia, hyposmia, dysgeusia, paresthesia, hair loss, degradation of vision, tachycardia, allergic reactions, menstrual cycle impairments, erectile dysfunction, panic attacks, suicidal ideation, depression and refusal to eat meat. Conclusions: No associations were found between clinical symptomatology and the severity of COVID-19, the volume of lung tissue affected, or different periods of postcovid syndrome. Cortexin was found to be effective at doses of 10 and 20 mg for correcting the cognitive and asthenic manifestations of PCS. Cortexin was found to have anti-anxiety, antidepressant, and anxiolytic effects, which were more marked at the 20-mg dose.

The effect of renin-angiotensin-aldosterone system blockers on the course of COVID-19 in patients with arterial hypertension

Objective. To determine the presence or absence of the effect of therapy with renin-angiotensin-aldosterone system (RAAS) blockers in patients with COVID-19.Design and methods. We examined 57 patients who were treated in a medical unit at the FGAU CEC “Patriot” in the period from October to November 2020, with the diagnosis of “New coronavirus infection” and differed in the prescribed antihypertensive therapy. In group 1, drugs that affect the RAAS were used to treat hypertension before COVID-19 onset and during the treatment of COVID-19. In group 2, other drugs were used as the main antihypertensive agents before and during treatment for COVID-19. The severity of pneumonia in patients according to the results of computed tomography was 1–2. The patients were monitored for anthropometric indicators, body temperature, and laboratory data.Results. Groups 1 and 2 are comparable, differing only by height, but not by body mass index. The duration of treatment in group 2 was 1–2 days shorter than in group 1, but the result is not statistically significant due to the small sample. Thus, the hypothesis that differences between previous and ongoing antihypertensive therapy throughout the COVID-19 treatment period may affect the course and effectiveness of treatment has not been confirmed.Conclusions. Concomitant antihypertensive therapy with RAAS blockers does not alter the course of COVID-19 infection in patients. The duration of COVID-19 in patients receiving RAAS system blockers may be one day longer than for patients receiving other antihypertensive therapy.

The Moderating Effect of Resilience on Mental Health Deterioration among COVID-19 Survivors in a Mexican Sample.

Resilience has been reported to be a protective psychological variable of mental health; however, little is known about its role in COVID-19 survivors. Thus, in this study, we aimed to evaluate the levels of depression, anxiety, stress, traumatic impact, and resilience associated with COVID-19, as well as to investigate the role of resilience as a moderating variable. A sample of 253 participants responded to an online survey; all were previously diagnosed with COVID-19 by a nasopharyngeal swab RT-PCR test, were older than 18 years, and signed an informed consent form. Significant negative correlations were found between resilience and the mental health variables. Higher resilience was significantly related to a lower impact of the event, stress, anxiety, and depression when the number of symptoms was low. Only when the duration of COVID-19 was short and resilience levels were medium or high was psychological distress reduced. Moreover, resilience moderated the effects of COVID-19 on mental health, even if a relapse occurred. The results emphasize the need for interdisciplinary interventions aimed at providing COVID-19 patients with psychological and social resources to cope with the disease, as well as with probable relapses.

Potential Causes Related to Stock Market Volatility During COVID-19: Insights into the Performances in the Us

<p>The research aims to figure out the significant factors causing the volatility moves in the period from Feb 10 to Dec 28, 2020, which covers the outbreak and duration of COVID-19 in 2020, among the candidates: number of reports (cases, deaths, tests, and infection rate), number of medical resources needed (all beds needed, ICU beds needed, and invasive ventilators needed), and people’s anticipation toward reality (stock market, the pandemic, state of the economic and personal finance). After performing OLS regressions with stepwise regressions forward further, whose independent variables are chosen based on the values of VIF, we conclude that people’s focus on coronavirus is the most significant factor that induces the volatility, and the VIX values evolve dynamically. Nevertheless, the conclusions are somehow not robust as expected: in the second half of the period, not only none of the candidates are shown to have any influence on the volatility, but also the VIX series is proved to be not autocorrelated. By the results of the study, it is important not only to control the further spread of the pandemic but also to find approaches to stabilize people’s emotions towards the aspects of life which are affected by the pandemic. Apart from the meaningful insights from the research, the research paves the way for further studies in the future.</p>

The Effect of Antibiotics and Drugs on the Duration of COVID-19 in Hospitalized Patients

This is a single center, retrospective, observational study carried out in Ohud hospital, the main referral hospital for SARS-CoV-2 infections in the region of Madinah, Kingdom of Saudi Arabia. The study was carried on hospitalized patients with moderate to severe symptoms, including critically ill patients in the intensive care unit mostly of them requiring oxygen or mechanical ventilator support. Medical records from 432 cases were investigated showing that the majority of infected population were adults with an average age of 48 years, where 68.3% were males and the mortality rate was 5.6%. Duration of the disease was determined as the period between the first positive and the first negative PCR results. Patients who received antibiotics or Metoclopramide showed shorter duration of the disease time course while those who received Hydroxychloroquine, Omeprazole or Calcium exhibited longer durations before obtaining a negative PCR result. Regression analysis furtherly confirmed that antibiotics administration was associated with shorter course of disease while hydroxychloroquine or omeprazole were correlated with longer duration of the disease. Antiviral drugs, however, showed no correlations to the COVID-19 duration of stay in hospital. Finally, combining antibiotics and antiviral agents did not result in a better outcome, suggesting that the use of antibacterial agents helps in the recovery of SARS-CoV-2 patients.

Sports cardiology 2021 - what's new?

The recently published guidelines "Sports cardiology and exercise in patients with cardiovascular disease" (2020) are the first of a kind by the European Society of Cardiology (ESC). The guidelines provide comprehensive training recommendations for patients with cardiovascular diseases or risk factors, covering the entire spectrum of cardiovascular diseases with case-specific recommendations for recreational and competitive sports.The ESC recognizes exercise as an essential part of both prevention and therapy of cardiovascular diseases, that - comparable to drug therapies - requires correct prescription.The initial cardiac examination is used for individual risk stratification and is indispensable for individualized training recommendations addressing training frequency, duration and intensity, as well as type of sport.Thus, the question is not whether a patient with cardiovascular disease shall be allowed to exercise, but rather how he can safely perform it. Only in exceptional cases exercise therapy is (temporarily) contraindicated.COVID-19 can lead to cardiovascular complications even in asymptomatic and mild disease courses. Before resuming intense sporting activities, different return-to-sports protocols have been introduced. The current consensus is that the extent of these examinations should be based on symptoms, severity and duration of COVID-19 and that individual return-to-training recommendations should be given.

COMPARISON OF EMERGENCY SURGERIES UNDER SPINAL ANESTHESIA IN COVID-19 PANDEMIC WITH PRE-COVID PERIOD IN A TERTIARY CARE HOSPITAL OF A DEVELOPING COUNTRY

Objective: To compare emergency surgeries under spinal anesthesia in COVID-19 pandemic with pre-COVID period in a tertiary care hospital of a developing country.
 Study Design: Prospective observational study.
 Place and Duration of Study: Main Operation Theatre, Frontier Corps Hospital Quetta, from Mar to May 2020.
 Methodology: All emergency surgeries done under Spinal Anesthesia, were compared to emergency cases done in the preCOVID period. Anesthesia notes were reviewed. Emergency cases done under general anesthesia and personal protective equipment worn were also noted. Ages of the patients were from 18-75 years. Spinal anesthesia was performed by consultant anesthesiologist.
 Result: Among total cases, 260 emergency cases were performed in the main operation theatre during the 3 months of preCOVID period as compared to only 89 cases in the 3 months duration of COVID-19. Spinal anesthesia was used in 154 (59.2%) cases in the pre-COVID study period, while in COVID-19 pandemic 77 (86.5%) emergency cases were performed under spinal anesthesia.
 Conclusion: Spinal anesthesia has a significant role in the surgical management of patients in pre-COVID and especially in COVID pandemic. It provides high-quality perioperative care for patients whilst minimizing exposure to staff and utilization of scarce resources of personal protective equipment.

Post-acute sequelae of COVID-19 in a non-hospitalized cohort: Results from the Arizona CoVHORT.

Clinical presentation, outcomes, and duration of COVID-19 has ranged dramatically. While some individuals recover quickly, others suffer from persistent symptoms, collectively known as long COVID, or post-acute sequelae of SARS-CoV-2 (PASC). Most PASC research has focused on hospitalized COVID-19 patients with moderate to severe disease. We used data from a diverse population-based cohort of Arizonans to estimate prevalence of PASC, defined as experiencing at least one symptom 30 days or longer, and prevalence of individual symptoms. There were 303 non-hospitalized individuals with a positive lab-confirmed COVID-19 test who were followed for a median of 61 days (range 30–250). COVID-19 positive participants were mostly female (70%), non-Hispanic white (68%), and on average 44 years old. Prevalence of PASC at 30 days post-infection was 68.7% (95% confidence interval: 63.4, 73.9). The most common symptoms were fatigue (37.5%), shortness-of-breath (37.5%), brain fog (30.8%), and stress/anxiety (30.8%). The median number of symptoms was 3 (range 1–20). Amongst 157 participants with longer follow-up (≥60 days), PASC prevalence was 77.1%.