Dual System Research Articles

Design of actuator motor acceleration model in dual axis tracker movement for stand-alone PV system

Stand-alone photovoltaic system or PV is a power generation technology with potential that is environmentally friendly and also one of the solutions for saving high electricity rates today. However, problems that often occur due to weather fluctuations that are always changing, especially North Sumatra, Indonesia result in the conversion produced by solar cells not being optimal. Therefore, it is necessary to do a new model with a dual tracker system and the development of accelerator motor actuators so that the resulting energy conversion is more optimal. The result of optimizing the reliability of the polycrystalline type solar panel which is designed with an additional photovoltaic tracker system to maximize the conversion of solar energy to solar panels is to obtain an output power of 303.72 volts DC and 267.52 volts DC in the position where the tracker is not used. Then the percentage increase in energy reached 29.80%. Dual axis tracker technology is able to maximize energy conversion in improving PV usage performance. The implementation of a stand-alone PV system will be beneficial if the installation is in Indonesian territory, especially in disadvantaged, frontier and outermost areas.

Cortical and Subcortical Mechanisms of Orthographic Word-form Learning.

We examined the initial stages of orthographic learning in real time as literate adults learned spellings for spoken pseudowords during fMRI scanning. Participants were required to learn and store orthographic word forms because the pseudoword spellings were not uniquely predictable from sound to letter mappings. With eight learning trials per word form, we observed changes in the brain's response as learning was taking place. Accuracy was evaluated during learning, immediately after scanning, and 1 week later. We found evidence of two distinct learning systems-hippocampal and neocortical-operating during orthographic learning, consistent with the predictions of dual systems theories of learning/memory such as the complementary learning systems framework [McClelland, J. L., McNaughton, B. L., & O'Reilly, R. C. Why there are complementary learning systems in the hippocampus and neocortex: Insights from the successes and failures of connectionist models of learning and memory. Psychological Review, 102, 419-457, 1995]. The bilateral hippocampus and the visual word form area (VWFA) showed significant BOLD response changes over learning, with the former exhibiting a rising pattern and the latter exhibiting a falling pattern. Moreover, greater BOLD signal increase in the hippocampus was associated with better postscan recall. In addition, we identified two distinct bilateral brain networks that mirrored the rising and falling patterns of the hippocampus and VWFA. Functional connectivity analysis revealed that regions within each network were internally synchronized. These novel findings highlight, for the first time, the relevance of multiple learning systems in orthographic learning and provide a paradigm that can be used to address critical gaps in our understanding of the neural bases of orthographic learning in general and orthographic word-form learning specifically.

Puppy whines mediate maternal behavior in domestic dogs

In mammals, offspring vocalizations typically encode information about identity and body condition, allowing parents to limit alloparenting and adjust care. But how do these vocalizations mediate parental behavior in species faced with the problem of rearing not one, but multiple offspring, such as domestic dogs? Comprehensive acoustic analyses of 4,400 whines recorded from 220 Beagle puppies in 40 litters revealed litter and individual (within litter) differences in call acoustic structure. By then playing resynthesized whines to mothers, we showed that they provided more care to their litters, and were more likely to carry the emitting loudspeaker to the nest, in response to whine variants derived from their own puppies than from strangers. Importantly, care provisioning was attenuated by experimentally moving the fundamental frequency (fo, perceived as pitch) of their own puppies' whines outside their litter-specific range. Within most litters, we found a negative relationship between puppies' whine fo and body weight. Consistent with this, playbacks showed that maternal care was stronger in response to high-pitched whine variants simulating relatively small offspring within their own litter's range compared to lower-pitched variants simulating larger offspring. We thus show that maternal care in a litter-rearing species relies on a dual assessment of offspring identity and condition, largely based on level-specific inter- and intra-litter variation in offspring call fo. This dual encoding system highlights how, even in a long-domesticated species, vocalizations reflect selective pressures to meet species-specific needs. Comparative work should now investigate whether similar communication systems have convergently evolved in other litter-rearing species.

Next-Generation Dual Transceiver FSO Communication System for High-Speed Trains in Neom Smart City

Smart cities like Neom require efficient and reliable transportation systems to support their vision of sustainable and interconnected urban environments. High-speed trains (HSTs) play a crucial role in connecting different areas of the city and facilitating seamless mobility. However, to ensure uninterrupted communication along the rail lines, advanced communication systems are essential to expand the coverage range of each base station (BS) while reducing the handover frequency. This paper presents the dual transceiver free space optical (FSO) communication system as a solution to achieve these objectives in the operational environment of HSTs in Neom city. Our channel model incorporates log-normal (LN) and gamma–gamma (GG) distributions to represent channel impairments and atmospheric turbulence in the city. Furthermore, we integrated the siding loop model, providing valuable insights into the system in real-world scenarios. To assess the system’s performance, we formulated the received signal-to-noise ratio (SNR) of the network under assumed fading conditions. Additionally, we analyzed the system’s bit error rate (BER) analytically and through Monte Carlo simulation. A comparative analysis with reconfigurable intelligent surfaces (RIS) and relay-assisted FSO communications shows the superior coverage area and efficiency of the dual transceiver model. A significant reduction of up to 76% and 99% in the number of required BSs compared to RIS and relay, respectively, is observed. This reduction leads to fewer handovers and lower capital expenditure (CAPEX) costs.

Effect of LRRC15 on autophagy in A549 cells.

Idiopathic pulmonary fibrosis (IPF) is a progressive, chronic, and irreversible interstitial lung disease with unknown cause. To explore the role and regulatory mechanism of leucine-rich repeat-containing protein 15 (LRRC15) in IPF, bleomycin (BLM)-induced pulmonary fibrosis in mouse and A549 cells were constructed, and the expression of LRRC15 were detected. Then, MTT, GFP-RFP-LC3 dual fluorescent labeling system and Western blotting were used to investigate the effects of LRRC15 on cell activity and autophagy after transfection of siLRRC15, respectively. The results indicated that the expression of LRRC15 was significantly increased after the BLM treatment in mouse lung tissue and A549 cells. The designed and synthesized siLRRC15 followed by transfection into A549 cells resulted in a dramatic reduction in LRRC15 expression and partially restored the cell damage induced by BLM. Moreover, the expression of LC3-II and P62 were up-regulated, the amount of autophagosome were increased by GFP-RFP-LC3 dual fluorescent labeling assay after BLM treatment. Meanwhile, this study also showed that the key autophagy proteins LC3-II, ATG5 and ATG7 were up-regulated, P62 was down-regulated and autophagic flux were enhanced after further treatment of A549 cells with siLRRC15. The above findings suggest that LRRC15 is an indicator of epithelial cell damage and may participate in the regulation of fibrosis through autophagy mechanism in IPF. This study provides necessary theoretical basis for further elucidating the mechanism of IPF.

Experimental investigation of a sun tracking concentrated solar still with economic analysis

The current paper evaluated experimentally an innovative sun tracking concentrated solar still under Egyptian climatic conditions during the summer of 2022. The proposed system consists of a 120-cm-diameter parabolic reflector mirror that tracks the sun using a dual axis tracking system, a cylindrical solar still with a volume of 3.7 L positioned in its focal point, and a concentration ratio of 12.5. The performance of the concentrated solar still was investigated in the context of two critical parameters. First, three feed water salinity (17, 27, 37) ppt samples were evaluated, followed by four percentages of saline water filling ratio (26.5, 39.8, 53.1, 66.3)%. Increasing the salinity of the feed water had no effect on solar still productivity, but increasing the saline water filling ratio did. The daily cumulative productivity of the system was 6 kg/m2 with an optimal filling ratio of 53.1%, a daily efficiency of 42.88%, and an average cost of freshwater production of 0.0489 $/L. The proposed system also had the highest instantaneous efficiency of 61.77% and the highest distilled water productivity rate of 0.941 kg/h m2.

On a fully coupled nonlocal multipoint boundary value problem for a dual hybrid system of nonlinear q-fractional differential equations

On a fully coupled nonlocal multipoint boundary value problem for a dual hybrid system of nonlinear <i>q</i>-fractional differential equations

A whole process study of dual microalgae cultivation coupled to domestic wastewater treatment and wheat growth.

The multiple microalgal collaborative treatment of domestic wastewater has been extensively investigated, but its whole life cycle tracking and consequent potential have not been fully explored. Herein, a dual microalgal system was employed for domestic wastewater treatment, tracking the variation in microalgal growth and pollutants removal from shake flask scale to 18L photobioreactors scales. The results showed that Chlorella sp. HL and Scenedesmus sp. LX1 combination had superior growth and water purification performance, and the interspecies soluble algal products promoted their growth. Through microalgae mixing ratio and inoculum size optimized, the highest biomass yield (0.42±0.03g/L) and over 91 % N, P removal rates were achieved in 18L photobioreactor. Harvested microalgae treated in different forms all promoted wheat growth and suppressed yellow leaf rate. This study provided data support for the whole process tracking of dual microalgal system in treating domestic wastewater and improving wheat growth.

Analysis and design of wireless power transfer system with anti-misalignment constant voltage output characteristics

Analysis and design of wireless power transfer system with anti-misalignment constant voltage output characteristics

CO2 photoreduction integrated with oxidative coupling of amines over WO3/Cu(BTC) nanocomposite

Here, we report an efficient integrated CO2 photoreduction to methanol accompanied with the simultaneous oxidation of benzyl amines to corresponding imines using quadrangular WO3 nanoplates grafted with Cu(BTC) as a photocatalyst under visible light, enabling to provide efficient use of the photogenerated electrons and holes. Under the optimized reaction conditions, the maximum yield of methanol and N-(4-methoxybenzyl)-1-(4-methoxyphenyl)methanimine was found to be 642 μmol-g−1 and 98 %, respectively. The developed integrated dual functional system comprising CO2 reduction coupled with the oxidative organic synthesis opens a new window for value chain up gradation at both ends using sustainable solar energy.

Dual engineered bacteria improve inflammatory bowel disease in mice.

Currently, there are many different therapies available for inflammatory bowel disease (IBD), including engineered live bacterial therapeutics. However, most of these studies focus on producing a single therapeutic drug using individual bacteria, which may cause inefficacy. The use of dual drugs can enhance therapeutic effects. However, expressing multiple therapeutic drugs in one bacterial chassis increases the burden on the bacterium and hinders good secretion and expression. Therefore, a dual-bacterial, dual-drug expression system allows for the introduction of two probiotic chassis and enhances both therapeutic and probiotic effects. In this study, we constructed a dual bacterial system to simultaneously neutralize pro-inflammatory factors and enhance the anti-inflammatory pathway. These bacteria for therapy consist of Escherichia coli Nissle 1917 that expressed and secreted anti-TNF-α nanobody and IL-10, respectively. The oral administration of genetically engineered bacteria led to a decrease in inflammatory cell infiltration in colon and a reduction in the levels of pro-inflammatory cytokines. Additionally, the administration of engineered bacteria did not markedly aggravate gut fibrosis and had a moderating effect on intestinal microbes. This system proposes a dual-engineered bacterial drug combination treatment therapy for inflammatory bowel disease, which provides a new approach to intervene and treat IBD. KEY POINTS: • The paper discusses the effects of using dual engineered bacteria on IBD • Prospects of engineered bacteria in the clinical treatment of IBD.

Performance-Based Seismic Design for Bridge Bents Retrofitted with BRBs Using the Ductility Demand Spectra of SDOF Oscillators with Bilinear Fuses

ABSTRACT Reinforced concrete bridge bents with double columns in bridge substructures are commonly used, but it has suffered severe damage during strong earthquakes. The seismic retrofit with structural fuses is used to effectively mitigate seismic damage of bridge bents. To obtain the displacement ductility demand for dual systems including the primary structure (PS) and structural fuses (SF), the corresponding ductility demand factor spectra were developed. The interaction between the PS and SF is described by defining two parameters of dual systems: the yield displacement ratio (α) and the initial stiffness ratio (β), and the influence of α, β, and strength reduction factor on the ductility demand factor spectra are also analyzed. For seismic retrofitting in bridge bents, buckling-restrained braces (BRBs) are used as energy dissipation fuses, and the steel core lengath of BRBs with three configurations forms, including diagonal, inverted-V, and toggle systems, are also explored. Then, based on the structural fuses concept and ductility demand factor spectra of dual systems, a performance-based seismic design procedure is proposed for bridge bents retrofitted with BRBs to ensure that the bridge bents maintain the target ductility under design-level earthquakes. Finally, the procedure was utilized to design the bridge bents with BRBs, and the procedure’s feasibility was verified by nonlinear time-history analysis.

Weak signal detection method based on nonlinear differential equations

With the rapid development of computer network technology, it is often necessary to collect weak signals to collect favorable information. The development of signal detection technology is ongoing; however, various issues arise during the detection process. These issues include low efficiency and a high signal noise threshold. However, many problems will be encountered in the process of detection. In order to solve these problems, the nonlinear chaos theory is introduced to detect signals, and the simulation experiments of weak pulse signals and weak partial discharge signals are carried out respectively. The experimental results showed that the detection effect was remarkable in the quasi periodic state, and it had a good detection effect for weak pulse signals. At a signal-to-noise ratio of -25 dB, double coupling system, two-way ring coupling system, and single ring coupling system displayed detection success rates exceeding 98%. Meanwhile, the detection success rate of the strong coupling system was only 12%. Even at a noise signal ratio as low as -40 dB, the dual coupling system still maintained a detection success rate above 80%. The simulation results of partial discharge signal detection showed that there was a high fluctuation only at 2 ms, and the rest was basically stable at about 0 V, indicating that the system had a strong suppression effect on Gaussian white noise. When comparing the simulation results of the detection of the new chaotic system and the double coupling system, it was found that the new chaotic system has a superior impact in detecting weakly attenuated partial discharge signals. Through analysis of the system’s dynamic behavior, the research confirms its rich dynamic characteristics and sheds light on the reasons for phase state mutation and missed detection. The noise system is utilized for comparing the performance of various systems, with the goal of enhancing the system’s detection capability.

Streptomyces phaeochromogenes BV-204, K-1115A Anthraquinone-Producing Strain: A New Protein Biosynthesis Inhibitor.

In the search for new antibiotics, it is a common occurrence that already known molecules are "rediscovered" while new promising ones remain unnoticed. A possible solution to this problem may be the so-called "target-oriented" search, using special reporter microorganisms that combine increased antibiotic sensitivity with the ability to identify a molecule's damaging effect. The use of such test organisms makes it possible to discover new promising properties even in known metabolites. In this study, we used a high-throughput screening method based on the pDualrep2 dual reporter system, which combines high sensitivity through the use of modified strains of test organisms and makes it possible to easily and accurately identify the interaction mechanisms of a substance and a bacterial cell at the initial stages of screening. This reporter system is unknown in Russia and is significantly superior to its global analogues. In the system, translation inhibition induces the expression of the fluorescent protein Katushka2s, while DNA damage is induced by TurboRFP. Using pDualrep2, we have isolated and described BV-204, an S. phaeochromogenes strain producing K-1115A, the biologically active substance that we have previously described. In our study, K-1115A for the first time has demonstrated antibiotic activity and an ability to inhibit bacterial translation, which was confirmed in vitro in a cell-free translation system for FLuc mRNA. K-1115A's antibacterial activity was tested and confirmed for S. aureus (MRSA) and B. subtilis, its cytotoxicity measured against that for the HEK293 cell line. Its therapeutic index amounted to 2 and 8, respectively. The obtained results open up prospects for further study of K-1115A; so, this can be regarded as the basis for the production of semi-synthetic derivatives with improved therapeutic properties to be manufactured in dosage forms.

NOE analysis using dual injection DNP‐NMR for studies of solvent–solute interactions at low concentrations

AbstractDynamic nuclear polarization (DNP) offers significant signal enhancement compared to conventional nuclear magnetic resonance (NMR) in measuring the nuclear Overhauser effect. Owing to this enhancement, DNP enables the quantitative analysis of solvent–solute interactions, which are typically challenging to assess using standard NMR techniques. However, current experimental setups generally require the use of samples with relatively high solute concentrations because of large dilution factors. This limits the studies on solvent–solute interactions for bio‐related molecules, particularly those with low solubility. In such cases, the concentration of solute post‐dilution often falls below the detection limits. Herein, we introduce a novel dual injection system designed to considerably increase the dilution factor, thereby enabling the use of samples with lower solute concentrations while maintaining detectable signal levels. The effectiveness of this system was demonstrated in experiments using trifluoroacetic acid at concentrations 50 times lower than those used in the conventional method.

A bifid ureter originating from separate major calyx and renal pelvis with dual calyceal systems: a case report.

Present case report describes a case of bifid ureter arising directly from separate calyces and renal pelvis of the kidney. Incomplete ureter duplication on the left side in a 78-year-old male cadaver was found during an anatomy class. These ureters converged in a Y-shaped pattern just above the level of the anterior superior iliac spine. In the coronal section of the kidney, the anterior ureter arose from a renal pelvis that was divided into two major calyces in the lower two-thirds of the kidney. On the other hand, the posterior ureter was directly connected to a major calyx in the upper third of the kidney, without the formation of a renal pelvis. This anatomical variation has implications for diagnostic approaches, especially in the use of imaging techniques by urologists for the insertion of stents in the treatment of phyelonephritis.

Generation of entanglement and quantum steering via Josephson parametric amplifier in a dual cavity-magnon system

In the two microwave (MW) cross-shaped cavity magnon system, we describe a method to produce multipartite entanglement and quantum steering. To achieve squeezed states of the magnons, a Josephson parametric amplifier (JPA) creates a squeezed vacuum field that drives the two cavities. We theoretically demonstrate that the cavity-cavity entanglement can be generated at the resonance point, however, increasing the cavity and magnon decay rates generate the cavity-magnon entanglement. By changing the squeezing parameter and increasing the decay rates, we can transfer the cavity-cavity entanglement to cavity-magnon entanglement. Furthermore, the cavity-cavity entanglement (survive up to 2.8 K) was not only found to be much stronger but also more robust as compared to cavity-magnon entanglement (survive up to 0.4 K). More importantly, the genuine photon-magnon-photon tripartite entanglement could be achieved, which is robust against thermal fluctuations and depends strongly on the squeezing parameter. Furthermore, for the current dual cavity-magnon system, two-way quantum steering is found when the optomagnonical couplings are equal. The current study offers a straightforward and practical method for achieving multipartite quantum correlations.

Medial-pivot total knee arthroplasty enhances tibiofemoral axial rotation stability in weight-bearing mid-range flexion compared to posterior-stabilised system.

Total knee arthroplasty (TKA) stands as a primary intervention for severe knee ailments, yet concerns remain regarding postoperative patient satisfaction and flexion instability. This study aims to evaluate the in-vivo kinematics of medial-pivot (MP) and posterior-stabilised (PS) designs during step-up activity, in comparison to the kinematics of the nonoperated contralateral knee. Sixteen patients with PS-TKA and 14 with MP-TKA were retrospectively examined. Clinical outcomes were assessed using patient-completed questionnaires. Motion during step-up was captured using a dual fluoroscopic system. Statistical analysis was applied to evaluate the in-vivo tibiofemoral six-degree-of-freedom kinematics and articular contact positions between the two groups. Despite being older, patients in the MP group reported higher postoperative subjective scores for weight-bearing functional activities. The axial rotation centres of MP-TKA located on the medial tibial plateau exhibited less variance compared to PS-TKA and contralateral knees. Compared to the contralateral knee (contralateral to medial-pivot [C-MP] or contralateral to posterior-stabilised [C-PS]), the MP group exhibited limited range of motion in terms of anteroposterior translation (MP: 3.6 ± 1.3 mm vs. C-MP: 7.4 ± 2.5 mm, p < 0.01) and axial rotation (MP: 6.6 ± 1.9° vs. C-MP: 10.3 ± 4.9°, p = 0.02), as well as in the PS group for anteroposterior translation (PS: 3.9 ± 1.7 mm vs. C-PS: 7.2 ± 3.7 mm, p < 0.01). The MP group with better postoperative ratings demonstrated a more stable MP axial rotation pattern during step-up activity compared to the PS group, underscoring the pivotal role of prosthetic design in optimising postoperative rehabilitation and functional recovery. Level III.

Tsunami Ping-Pong: Generating The Whole Tsunami Event

Considerable progress has been made over the past two decades in modelling representative tsunami waves in the laboratory. Developments such as the pneumatic tsunami simulator, TS, (Chandler et al, 2021), large wave paddles (Schimmels et al, 2016) and pump driven systems (Goseberg et al, 2013) have allowed full incident tsunami time series to be reproduced at large enough scales to provide reliable physical modelling data. These developments have enabled new insights into the time-varying influence of tsunami waves on run-up (McGovern et al, 2018), buildings (Foster et al, 2017), coastal structures (McGovern et al, 2022) and in particular the scour of sediments around these structures (McGovern et al, 2019). These advances are changing the way engineers and others design and plan for tsunami. However we are still only modelling ‘half the story’. In all existing published studies, the experiments simulated the effect of a single incident wave. We have so far ignored two significant elements of real tsunami events. Firstly, the rundown or return flow and secondly, the effect of multiple waves within a wave train. Both these aspects are difficult to model physically, particularly as the return flow and subsequent waves require a representative topography downstream of a test section. In most facilities there is not enough flume left to create this overland topography. In addition, changing this bathymetry to represent different scenarios such as a coastal plain or a small foreshore and an inland cliff, requires significant modelling effort and cost. To solve these challenges we propose the use of two TSs facing each other with the test section in between. This concept is shown in Figure 1. This extended abstract presents data from initial trials of the dual TS system conducted at HR Wallingford in 2023 during a three-day test window as part of the MAKEWAVES collaboration. The importance of simulating the return flow from a tsunami is demonstrated through its influence on scour around a rectangular building.

Caffeic acid phenethyl ester (CAPE) Chitosan capped ZnO nanoparticles: Preparation, characterization, and its potential for the treatment of prostate cancer

The synthesis of zinc oxide nanoparticles/chitosan (ZnONPs/CS) formulation loaded with Caffeic acid phenethyl ester (CAPE) was performed to evaluate its prostate cancer treatment efficiency within the scope of this research. It has been hypothesized that a dual active materials delivery system containing ZnO and CAPE loaded Chitosan (CS) nanoparticles has better bioavailability compared to single one against to cancer cells. ZnONPs were synthesized between 45 and 60 nm particle sizes and then they were capped with CS biodegradable polymer prior to load with CAPE bioactive molecule. ZnONPs/CS-CAPE system was characterized by using Fourier Transform Infrared (FTIR) for structural elucidation, Scanning Electron Microscope (SEM) for particle size determination, High Performance Liquid Chromatography (HPLC) system for determination of CAPE amount. 131I CAPE and 131I ZnONPs/CS-CAPE labeled by the Iodogen method with 131I were used in-vitro cell culture experiments. Cell viabilities (%) of CAPE and ZnONPs/CS-CAPE were examined using Cell Counting Kit-8 assay on PC-3 (human adenocarcinoma prostate), LnCaP (human carcinoma prostate), and RWPE-1 (human normal prostate). IC50 values of ZnONPs /CS -CAPE on all cells were found 2-fold lower than neat CAPE. Based on the FTIR data, the most significant spectral changes (lipid, protein, nucleic acids, glycogen) were monitored for the PC-3 and LnCaP cancer cells incubated with ZnONPs/CS-CAPE samples while being exposed to neat CAPE molecules caused small cellular changes when compared to RWPE-1 healthy cell lines.