Dual-source Radiofrequency Transmission Research Articles

Effect of Dual-Source Radiofrequency Transmission on Left Ventricular Measurements and Measurement Reproducibility at 3.0 T Cardiac MR Imaging: Comparison with Conventional Single-Source Transmission Reference

To prospectively assess effect of dual-source radiofrequency (RF) transmission on left ventricular (LV) measurements and measurements reproducibility at 3.0 T MR using balanced steady-state free precession (b-SSFP) cine imaging, compared to the conventional single-source RF transmission reference approach. Cardiac b-SSFP cine imaging was performed in 19 subjects at 3.0 T MR equipped with dual-source RF transmission. All images were analyzed to obtain LV end-diastolic volume, end-systolic volume, stroke volume, ejection fraction, mass, LV end-diastolic inferior wall thickness, and interventricular septal thickness. The difference of all LV measurements between the two imaging techniques was tested with the paired t test and the intertechnique agreement was tested through linear regression and Bland-Altman analyses. Additionally, repeated LV measurements were performed to determine intra and interobserver variability with the Bland-Altman method, the 95% limits of agreement, the coefficient of variation (CV) and the intraclass correlation coefficient. Compared to conventional single-source, dual-source slightly overestimated end-diastolic volume, end-systolic volume, and stroke volume (mean differences, 3.9 mL ± 9.7, 1.1 mL ± 2.6, and 2.8 mL ± 9.1, respectively; p > 0.05), resulting in a small but significant positive bias in ejection fraction (1.5% ± 2.6; p = 0.021). Mass was significantly smaller with dual-source than with single-source (-4.0 g ± 6.5, p = 0.001). Dual-source slightly underestimated interventricular septal thickness (-0.29 mm ± 0.6, p = 0.067) and significantly underestimated LV end-diastolic inferior wall thickness (-0.55 mm ± 0.4, p < 0.0001). The two techniques in measurements correlated highly (r2 = 0.81 to 0.96, p < 0.0001). Intra and interobserver variability in dual-source measurements was much lower than that in single-source, and variability values were <14.0%. Improved image quality of b-SSFP cine imaging at 3.0 T MR with dual-source RF transmission may provide more reproducible LV measurements compared to conventional single-source approach. Dual-source RF transmission also provides a reasonable estimate of the LV measurements.

High-dose dobutamine stress steady-state free precession (SSFP) cine MRI at 3T with patient adaptive local radiofrequency (RF) shimming using dual-source RF transmission.

To prospectively assess the feasibility, image quality, and diagnostic accuracy of high-dose dobutamine stress magnetic resonance imaging (DSMR) using steady-state free precession (SSFP) cine imaging at 3T applying a dual-source radiofrequency (RF) excitation magnetic resonance imaging (MRI) system with parallel transmission and patient adaptive local RF shimming. DSMR using SSFP cine imaging was performed in 44 patients at 3T scheduled for a clinically indicated coronary angiography. The effect of conventional versus dual-source RF transmission was assessed regarding homogeneity of the B1 field, contrast-to-noise ratios (CNRs) at rest, image quality, and diagnostic accuracy of DSMR using long and short axis. The mean percentage of the intended flip angle within the heart increased from 88 ± 9.1% with single-source to 103 ± 5.6% (P < 0.001) dual-source RF transmission. CNR increased for dual-source particularly at the apex (63.4 ± 24.2 vs. 36.5 ± 16.5, P < 0.001) but also at the base of the left ventricle (LV) (50.1 ± 14.8 vs. 39.3 ± 15.8, P < 0.001). Image quality of dual-source was higher both at rest (2.8 ± 0.5 vs. 2.6 ± 0.7, P < 0.001) and stress (2.5 ± 0.7 vs. 2.0 ± 1.0, P < 0.001). The number of segments with severe artifacts or nondiagnostic image quality at stress was lower with dual-source RF transmission (8% vs. 27%, P < 0.001). The diagnostic accuracy of DSMR in coronary territories using dual-source RF transmission was significantly higher (77% vs. 65%, P = 0.04). Patient adaptive local RF shimming using dual-source RF transmission provided significantly improved image quality and higher diagnostic accuracy of SSFP during DSMR at 3T compared to conventional RF transmission.

Dual-source RF transmission in cardiac SSFP imaging at 3 T: systematic spatial evaluation of image quality improvement compared to conventional RF transmission

The purpose of this investigation was to systematically evaluate the spatial distribution of image quality improvement with dual-source radiofrequency (RF) transmission in cardiac steady-state free precession sequences at 3.0 T. Imaging with and without dual-source RF transmission was performed in 30 patients. Contrast-to-noise ratio for the left ventricular myocardium was significantly higher using dual-source RF transmission, but improvement was not uniformly distributed. The posterior myocardium showed significantly less contrast-to-noise ratio gain than all other cardiac regions. Signal-to-noise ratio increase was higher in the right than in the left ventricle. Subjective image quality was significantly enhanced by parallel RF transmission.

Impact of 3.0 T Cardiac MR Imaging Using Dual-Source Parallel Radiofrequency Transmission with Patient-Adaptive B1 Shimming

ObjectivesTo prospectively evaluate the impact of 3.0 T Cardiac MR imaging using dual-source parallel radiofrequency (RF) transmission with patient-adaptive B1 shimming compared with single-source RF transmission in the RF homogeneity, image contrast and image quality.MethodsThe study was approved by the local institutional review board, and all subjects provided written informed consent. Fourteen healthy volunteers were examined at 3.0 T MR, with both the conventional single-source and the new dual-source RF transmission. B1 calibrations (RF shimming) of the heart region were performed to acquire a percent of the prescribed flip angle (FA) of B1 maps, which were used for quantitative assessment of RF homogeneity. Contrast ratios (CRs) between ventricular blood pool and septum were calculated on balanced-turbo field echo (B-TFE) cine images. The off-resonance artifacts of cine images were blindly assessed by two radiologists according to a 4-point grading-scale.ResultsA significantly lower mean coefficients of variance of the achieved FA with dual-source revealed better RF homogeneity compared to single-source (P = 0.0094). Dual-source RF shimming significantly increased the CRs (P<0.05) and reduced the off-resonance artifacts of B-TFE cine images (P<0.05). Inter-observer agreement for the off-resonance artifacts of B-TFE cine images was good to excellent (k >0.65).ConclusionsDual-source parallel RF transmission significantly improves the RF homogeneity, increases image contrast and reduces image artifacts of cardiac B-TFE images compared to single-source mode. This may be of value in reducing the observer-dependence of cardiac MR images and enhancing diagnostic confidence for clinical practice using CMR at 3.0 T.

Breast MR Imaging at 3 T with Dual-Source Radiofrequency Transmission Offers Superior B1Homogeneity: An Intraindividual Comparison with Breast MR Imaging at 1.5 T

To evaluate and compare B1 homogeneity for breast magnetic resonance (MR) imaging performed at 3 T with dual-source radiofrequency (RF) transmission to 1.5-T MR imaging and 3-T MR imaging with quadrature transmission. This prospective study received institutional review board approval and patients provided informed consent. Women (n = 25; mean age, 53 years; range, 30-68 years) suspected of having breast lesions underwent breast MR imaging examinations on comparable 1.5-T and 3-T clinical systems between February and May 2012. B1 maps were obtained at 1.5 T and at 3 T with quadrature and dual-source RF transmission. Intrabreast differences and differences in mean B1 values between right and left breasts were investigated by using two-sided multivariate analysis of variance with interaction; t tests were used to compare the differences between measured whole-breast mean B1 values and requested B1 values. With quadrature transmission at 1.5 T and 3 T, the mean B1 values showed a statistically significant difference: left-breast measured B1 was -8.9% of requested B1 value at 1.5 T and -13.7% at 3 T (P < .001), whereas right-breast measured B1 was +5.4% of requested B1 value at 1.5 T (P < .001) and +2.7% at 3 T (P = .01). With dual-source RF transmission at 3 T, mean B1 values across the breasts were not statistically different, nor were the measured B1 values compared with requested B1 values (left breast, -0.6%; right breast, -0.7%). At 3 T with dual-source transmission, slight intrabreast local variations in B1 were recorded. MR imaging at 3 T with dual-source RF transmission offered an overall B1 homogeneity for breast imaging that was better than that obtained at 1.5 T and with quadrature transmission.

Dual-source parallel RF transmission for diffusion-weighted imaging of the abdomen using different b values: Image quality and apparent diffusion coefficient comparison with conventional single-source transmission

To prospectively and intraindividually evaluate what effects dual-source parallel radiofrequency (RF) transmission have on image quality and apparent diffusion coefficient (ADC) of abdomen diffusion-weighted imaging (DWI) using different b values, compared with the single-source RF transmission. Eighteen healthy male volunteers were enrolled in this Health Insurance Portability and Accountability Act (HIPAA)-compliant Institutional Review Board (IRB)-approved study. Abdominal DWI was performed with dual-source and single-source RF transmission at 3.0 T using a series of b-value combinations: 0/100, 0/500, 0/800, and 0/100/800. RF field homogeneity, subjective image quality, and signal to noise ratio (SNR) of each abdominal organ were evaluated. ADC values were calculated for each abdominal organ. Wilcoxon test and repeated-measures analysis of variance was used to calculate statistical significance. The parallel RF transmission significantly improved homogeneity of the RF field (P = 0.0001-0.008) and subjective image quality (P < 0.0001) at each b value and also increased SNR. At lower and higher b value, the measured ADC of lateral left hepatic lobe and spleen between dual-source and single-source images were significantly different (P = 0.0001-0.047). At b = 0/500, there was no significant difference in ADC measurements between dual-source and single-source RF transmission for abdominal organs, except a slight statistically significant difference for spleen (P = 0.047). Parallel RF transmission significantly improved the image quality and homogeneity of the RF field. The RF transmission had a significant influence on measured ADC of lateral left hepatic lobe and spleen. At b = 0/500 the influence was minimum for all abdominal organs.

Dual-Source Radiofrequency Transmission with Patient-Adaptive Local Radiofrequency Shimming for 3.0-T Cardiac MR Imaging: Initial Experience

To evaluate the effect of dual-source parallel radiofrequency (RF) transmission with patient-adaptive local RF shimming on image quality, image contrast, and diagnostic confidence at routine clinical cardiac magnetic resonance (MR) imaging with use of a 3.0-T dual-channel transmit whole-body MR system. Written informed consent was obtained from all patients, and the study protocol was approved by the local institutional review board. Cardiac MR imaging was performed in 28 patients by using a 3.0-T MR unit equipped with a dual-source RF transmission system. The effect of conventional versus dual-source RF transmission on steady-state free precession (SSFP) cine sequences and turbo spin-echo (TSE) black-blood (BB) sequences was evaluated. The homogeneity of the B1 field and contrast-to-noise ratios (CNRs) were measured and tested for statistical significance with the paired t test. Images were analyzed qualitatively for homogeneity, the presence of off-resonance artifacts, and diagnostic confidence independently by two readers. Statistical significance was assessed with the Wilcoxon signed rank test. Inter- and intraobserver agreement was assessed with κ statistics. Quantitative image analysis revealed that B1 homogeneity and CNR were significantly improved for images acquired with dual-source RF transmission compared with conventional RF transmission (P = .005). The quality of SSFP and TSE BB images of the left and the right ventricles showed a significant improvement with respect to image homogeneity and diagnostic confidence as evaluated by the readers (P = .0001, κ > 0.74). As a side effect, off-resonance artifacts were significantly reduced on SSFP images (P = .0001, κ > 0.76). Dual-source parallel RF transmission significantly improves image homogeneity, image contrast, and diagnostic confidence compared with conventional RF transmission of cardiac SSFP and TSE BB sequences.

Liver MRI at 3.0 Tesla

To prospectively and intraindividually compare liver magnetic resonance imaging (MRI) using single-source and dual-source parallel radiofrequency (RF) transmissions at 3.0-T for image quality, lesion detectability, and lesion contrast. Ninety-nine patients with 139 liver lesions underwent liver MRI at 3.0-T. Two radiologists performed a consensus review of T2-weighted images (T2WI), heavily T2WI (HT2WI), gadoxetic acid-enhanced hepatobiliary images, and diffusion-weighted imaging using single-source and dual-source RF transmissions with regard to image quality and lesion detectability. Contrast ratios between liver lesions and liver parenchyma were also calculated. Image quality was better with dual-source than with single-source at T2WI and HT2WI (P < 0.05), but lesion detectabilities were similar for all sequences. There was no significant difference in mean contrast ratios for all sequences (P > 0.05). Dual-source RF transmission provides a better image quality with T2WI and HT2WI than with single-source. However, 2 techniques showed similar lesion detectability.

Focal Liver Lesions at 3.0 T: Lesion Detectability and Image Quality with T2-weighted Imaging by Using Conventional and Dual-Source Parallel Radiofrequency Transmission

To prospectively compare T2-weighted single-shot turbo spin-echo (TSE) sequences performed with parallel and conventional radiofrequency (RF) transmission at 3.0 T for liver lesion detection, image quality, lesion conspicuity, and lesion contrast. After written informed consent and institutional review board approval, 52 consecutive patients (32 men, 20 women; mean age, 56.6 years ± 13.7 [standard deviation]) underwent routine magnetic resonance (MR) imaging with a clinical 3.0-T unit. Two independent readers reviewed images acquired with conventional and dual-source parallel RF transmission for detection of focal liver lesions, with separate reading of a third radiologist, including all available imaging findings, clinical history, and histopathologic findings, as reference. Image quality and lesion conspicuity were rated on five- and three-point evaluation scales, respectively. Contrast ratios between focal liver lesions and adjacent liver parenchyma were calculated. Significance was determined by using nonparametric Wilcoxon signed-rank and marginal homogeneity tests. With the reference standard, 106 index lesions were identified in 22 patients. Detection rate significantly improved from 87% (92 of 106) to 97% (103 of 106) (reader 1) and from 85% (90 of 106) to 96% (102 of 106) (reader 2) with parallel RF transmission (reader 1, P = .0078; reader 2, P = .002). Quality of parallel RF transmission images was assigned scores significantly higher, compared with quality of conventional RF transmission images (mean for reader 1, 2.88 ± 0.73 vs 4.04 ± 0.44; mean for reader 2, 2.81 ± 0.72 vs 4.04 ± 0.39; P < .0001 for both). Lesion conspicuity scores were significantly higher on parallel RF transmission images, compared with conventional RF transmission images (mean for reader 1, 2.02 ± 0.64 vs 2.92 ± 0.27; mean for reader 2, 2.06 ± 0.67 vs 2.90 ± 0.30; P < .0001 for both). Contrast ratios were significantly higher with parallel RF transmission (P < .05). Compared with conventional RF transmission, parallel RF transmission significantly improved liver lesion detection rate, image quality, lesion conspicuity, and lesion contrast. http://radiology.rsna.org/lookup/suppl/doi:10.1148/radiol.11101429/-/DC1.

Dual-Source Parallel RF Transmission for Clinical MR Imaging of the Spine at 3.0 T: Intraindividual Comparison with Conventional Single-Source Transmission

To prospectively and intraindividually compare single-source radiofrequency (RF) excitation and dual-source parallel RF excitation in 3.0-T magnetic resonance (MR) imaging of the spine. Institutional review board approval and written informed patient consent were obtained. The RF power of a 3.0-T MR imaging system was distributed to two ports of the body coil of the system by using independent RF transmit channels. The maximum B(1) field strength for dual-source parallel RF excitation was maintained, as compared with single-source RF excitation. The repetition time was reduced according to the revised RF setup with dual-source parallel RF excitation while maintaining specific energy absorption limitations. Thirty patients were examined with and without dual-source parallel RF excitation. Diagnostic quality was assessed independently by two radiologists according to a four-point grading system. Image contrast ratios (CRs) were calculated between reference tissues and vertebrae for single-source RF excitation and dual-source parallel RF excitation. The mean acceleration achieved with dual-source parallel RF excitation was 36% (range, 18%-50%). The total imaging duration of a three-station total spinal examination was reduced by one-third by using dual-source parallel RF transmission. For all cases investigated, diagnostic image quality without significant differences between the two methods and with a good interobserver agreement was achieved (Kendall tau-b, 0.50-0.84). The observed image contrast changes were predominantly small (<0.10 in 15 of 24 CRs), though they were significantly different (P < .05). While shortening examination times by approximately one-third, the dual-source parallel RF transmission mode in MR imaging of the spine yielded diagnostic image quality comparable to that with the conventional single-source RF transmission mode.