This paper introduces a optical fiber temperature sensor based on vernier effect. The sensor's design consists of two integrated interferometric structures: the Mach-Zehnder interferometer (MZI) and the Fabry-Perot interferometer (FPI). Both interferometric structures exhibit symmetry, but they employ different types of optical fibers. Specifically, the MZI employs dual side hole fiber (DSHF), while the FPI is constructed using hollow-core optical fibers.Given the MZI's superior sensitivity to temperature changes compared to the FPI, it is chosen as the sensing arm. The paper conducts theoretical research and experimental validation of the optical fiber sensor's sensing principles. The findings reveal a sensor sensitivity of −305.42 pm/°C when measuring temperatures within the 32–50 °C range. Stability testing, repeatability testing, and response time testing are carried out using a constant temperature chamber and a water bath, affirming the sensor's excellent repeatability and stability, along with a response time faster than that of conventional thermometers.