In this paper, the combustion, heat-work conversion process and emission characteristic at high compression ratio for the spark ignition engine fuelled with E20 (20 % ethanol, 80 % gasoline) fuel were investigated under ultra-lean burn conditions. Specifically, the direct injection (DI) mode combined with port fuel injection (PFI) mode strategy was used in the experiments. In addition, the dual injection strategies were comprehensively investigated by using different fuel injection masses and injection timing. The results indicated that using optimal injection timing and reasonable injection masses can improve heat-work conversion efficiency and combustion efficiency, combustion stability in the test engine. Furthermore, under the lean combustion model, using earlier injection timing could not only inhibit the soot production, but also decrease the nitrogen oxides formation. Compared to the equivalence ratio at 0.82 and DI injection timing at 120 °CA bTDC, soot and NOX emissions were respectively reduced by 14.93 %–26.6 % and 39.84 %–73.56 % under the equivalence ratio at 0.685 and DI injection timing at 180 °CA bTDC. This study provides an optimization direction for the application of ethanol-gasoline blends in the internal combustion engine (ICE) engines for high efficiency and clean combustion.