Objective: To analyze the clinical effect of a simple egg membrane patch bridging method in repairing tympanic membrane perforation. Methods: A total of 93 tympanic membrane perforation patients admitted to the hospital between September 2022 and October 2023 were selected and divided into two groups according to the random number table method. The control group implemented the conventional treatment (n = 46 cases), and the patch group adopted the simple egg membrane patch bridging method (n = 47 cases). The healing rate of the tympanic membrane, the air-bone gap, the air conduction hearing threshold, the dry ear rate, and the incidence of complications in both groups were compared before and after treatment. Results: The healing rate of the tympanic membrane in the patch group was significantly higher than that of the control group (95.75% vs. 76.09%), with P < 0.05; there was no difference in the air-bone gap and air conduction hearing threshold levels between the two groups before treatment (P > 0.05), and the hearing indexes of the patch group were significantly lower than those of the control group 3 months after treatment (P < 0.05); the dry ear rate in the patch group was significantly higher than that of the control group after treatment (85.11% vs. 67.39%), and the total incidence of complications was also significantly lower than that of the control group (6.38% vs. 21.74%), with P < 0.05. Conclusion: The simple egg membrane patch bridging method is effective in repairing tympanic membrane perforation, which can effectively improve patients’ hearing levels and reduce the occurrence of post-treatment complications. Thus, it is worth popularizing and applying in the clinic.