ABSTRACT Green infrastructure in college campuses and their surrounding communities can bring public health benefits. Using green infrastructure measures in three university towns in Texas, United States, this study explores if and how green infrastructure can impact the physical and mental health status of university campus users in the community. Campus users were estimated as the number of visitors to campus using the SafeGraph mobility data, green infrastructure was measured with land cover and Landsat 8 satellite images, and health status was measured with the CDC health status data. The results of spatial error models suggest a significant moderating effect of tree canopy coverage indicating that green infrastructure could potentially benefit campus users’ health. This gives indirect evidence supporting the health-significant roles of the campus environment. For city planners and policymakers, increasing tree canopy coverage stands out as a promising green infrastructure planning and management strategy that can contribute to the health of campus users/communities.