This in vitro study evaluated Cenchrus purpureus (also called as Napier grass, elephant grass) extract’s antioxidant capacity and Phytoactive compounds. At present various parts of plant materials are becoming more popular for their health advantages as well as natural antioxidants. Ethanolic, methanolic, and aqueous extracts were examined to find out the total phenolic compound (TPC) (138.54±1.66, 77.5±1.73, 53.63±2.05 mg GAE/g), total flavonoids compound (TFC) (34.49±1.57, 28.24±3.35, 16.58±1.41 mg QE/g) of dry extract respectively, as well as antioxidant activity assay including DPPH scavenging capacity using C. purpureus extract. The ethanol extract of the three had an IC50 value of 39.41 µg/mL, similar to conventional ascorbic acid (31.46 µg/mL), suggesting its potential as a natural antioxidant. The study highlights the importance of examining diverse plant species to discover bioactive compounds that can be used to create innovative antioxidant agents for pharmaceuticals and functional food products.