The theoretical prediction model for the dynamic performance of a double panel system that takes into account the effect of mechanical links is developed in this paper. The double panel system is established considering both the vibro-acoustic coupling and the effect of the mechanical links between two flexible panels. Firstly, the modal characteristics of the double panel system are analyzed and compared with the results calculated by the finite element method. The accuracy and efficiency of the proposed model have been validated. Subsequently, the forced response of the double panel system under different external excitations is studied. It is shown that the mechanical link resulted in less response level of the double panel system in in low frequency range due to the structural path in the energy transmission of the double panel system. Finally, the effect of the mechanical link parameters on the dynamic performance of the double panel system is discussed. The results reveal that the stiffness coefficients, location distributions, and number of mechanical links can significantly influence the dynamic behavior of the double panel system. Therefore, the theoretical model can be used in optimization techniques to improve the sound transmission characteristics of the double panel system.