This study aimed to determine the dose of organic fertilizer adapted to the agroecological conditions of the Ferkéssédougou zone during the immature or vegetative phase with a view to improving agricultural productivity in rainfed sugar cane cultivation. The trial was conducted using a Fisher block experimental design with three (3) repetitions and six (6) treatments including the control treatment. The observations mainly focused on growth parameters. Health monitoring was also carried out to detect the presence of diseases. Regarding growth parameters, no statically significant effect of fertilizers was observed between treatments. However, the fertilizers used had a positive impact in terms of gain compared to the control. Thus, three (3) groups of fertilizers stood out. Group 1 was composed of mineral manure at the normal dose (350 kg/ha of NPK), organic manure at the normal dose (20t/ha), double dose of compost (40 t/ha) and the organo-mineral mixture, namely the normal dose of compost (20t/ha) + half dose of mineral fertilizer (175 kg/ha of NPK). These treatments promoted good emergence, good elongation of the plants with large diameters and a large number of internodes. Group 2, composed only of half a dose of compost (10 t/ha), allowed us to have a large number of stems. For group 3, corresponding to the control treatment, no growth parameter was correlated. No symptoms of major illnesses were observed during the observations. The M1400/86 variety used is resistant to termite attack.