Domestic Companies Research Articles

A Call for Innovative Translational and Clinical Research to Address China's Unique Cancer Landscape.

The Chinese government has, in recent decades, implemented various administrative laws and regulatory policies to expedite cancer therapeutic development, boosting research and development pipelines for domestic pharmaceutical companies and clinical trials; however, China faces unique challenges given the high prevalence of certain cancer types and distinct disease burdens, some of which are frequently overlooked by international pharmaceutical companies. Given the substantial unmet need for China-specific cancer care, it is crucial to promote the development of innovative pharmaceutical and clinical research in China, with a particular emphasis on addressing tumors most prevalent in its population.

Assessing the innovation climate of the region in the formation of innovative development programs

Subject. The article addresses economic and managerial relations arising in the process of building the innovative climate of the region. Objectives. The study aims to develop methodological provisions for assessing the innovative climate of the region in the formation of innovative development programs. Methods. We employ methods of systems analysis, comparison, abstraction, synthesis, generalization, structuring, and formalization. Results. We analyzed the existing methods for assessing the innovation climate in the region, proposed methodological provisions for this purpose. Our own algorithm to assess the innovation climate in the region considers stages of formation of innovative development programs. The paper offers a methodological approach to innovation climate assessment from a regional perspective. Conclusions. The formation of a favorable innovation climate in the region enables to enhance its competitiveness, improve the socio-economic situation, increase the share of domestic companies in the high-tech markets, ensure the implementation of innovative programs. Regular assessment of innovation climate is an essential procedure within the framework of managing the innovative development of the region.

The Importance of Public Relations in Building Corporate Reputation

This study examines the importance and value of Public Relations department (PR) in creating reputation within institutions such as commercial companies. Scholars and PR professionals emphasize that PR has a large impact on creating a two-way communication, promoting and maintain good reputation. The main purpose of this theoretical research is that how corporate reputation is seen and to what extent domestic companies in the Kurdistan Region pay attention to it. In this research, PR literature has been reviewed and it is argued that it can be used as a guideline for creating, developing and maintain institutional reputation.

Increasing labour productivity by providing innovative activities in when repair and service sector in livestock industry

At present, the Russian Federation and the Republic of Belarus are significantly behind the developed countries in terms of labor productivity and the share of domestic companies implementing technological innovations in the main sectors of the economy (especially in agriculture). One of the significant factors of this lag is the underestimation in past years of the promising potential of various innovative technologies and, as a consequence the very limited and slow implementation of breakthrough innovations in the most signifi cant sectors of the domestic economy. The decisive turn of the state economic policy of neighboring states in the area of deep technological transformation of all sectors of the economy is aimed at an innovative breakthrough and reaching advanced growth rates in the technological and economic development of fraternal countries. However, along with the introduction of the latest technologies the creation of completely new modern high-tech industries, which will require colossal fi nancial investments, the task of comprehensively and thoroughly exploring internal production reserves, searching for new forms and methods of improving the effi ciency of labour organization at existing enterprises, which will also bring a noticeable economic effect, remains relevant. This article describes in sufficient detail practical activities to improve and streamline accounting, planning, certifi cation, rationalization of workplaces of animal husbandry technical service organizations under the current conditions of the developing market. The results of the studies show that certifi cation and rationalization of workplaces are eff ective tools in fi nding internal production reserves to improve the use of labour resources, fi xed production assets, promotes the replacement of obsolete equipment, improves the relationship between workplaces, improves working conditions, and optimally balances the need for labour with the number of existing workplaces. This will significantly increase the overall efficiency of activities and competitiveness of service enterprises in the fi eld of animal husbandry.

MARKETING PRIORITIES OF COMPANIES IN THE INTERNATIONAL PHARMACEUTICAL MARKET

The article presents the current trends in the development of the international pharmaceutical market and systematizes the priority areas for implementing marketing approaches of the leading companies. The purpose of this article is to reveal the marketing priorities of international pharmaceutical companies in the context of global challenges. To study this issue, a set of methods was used, namely: analysis and synthesis, statistical method, process and institutionalist approaches, case study.The results of the study show that the international pharmaceutical market is characterized by a high level of dynamism, preservation of the priority share of economically developed countries in revenue generation, significant influence of regulatory mechanisms at the national and international levels, and active processes of economic competition through mergers and acquisitions. The analysis has shown that the modern concept of pharmaceutical marketing goes far beyond the established narrow interpretation as a set of tools for the production, sale and promotion of a pharmaceutical product and is characterized by a high level of adaptability to the challenges of the global marketing environment of the twenty-first century. The article reveals the focus of marketing of leading companies on such priorities as: scaling up marketing budgets, ensuring synergy between marketing and financial indicators of pharmaceutical companies, modernizing communication strategies by optimizing interaction with key opinion leaders, intensifying multichannel marketing, etc.The theoretical significance of the study is to deepen the concept of international marketing in the context of its individual sectoral manifestations, taking into account the influence of global competition, institutional regulations, and technological progress. The practical value is due to the potential of using local or regional benchmarking for domestic companies participating in the international pharmaceutical market. Prospects for further research are considered in the direction of assessing the mechanisms and effects of the introduction of marketing innovations in the field of international pharmaceuticals.

Artificial Intelligence's Impact on the Quality of External Auditor Reports in Saudi Domestic and International Audit Companies

This study investigates how external auditors perceive using artificial intelligence (AI) in the Kingdom of Saudi Arabia (KSA). It examines how external auditors perceive the impact of artificial intelligence on audit quality. It also seeks to determine whether local and foreign external auditors have different perspectives on AI's application and how it affects audit quality. Data were gathered using a questionnaire distributed to 44 regional and 20 international companies to accomplish research goals. The auditing manager, audit partners, senior auditors, and other staff members with possible accounting and auditing experience were among the participants. SPSS was used to analyze the data; in our analysis, we used descriptive analysis, validity and reliability testing, and data analysis to test our hypotheses. This investigation reveals that the perceived impact of artificial intelligence (AI) on audit quality does not vary significantly between domestic and foreign audit firms. Regarding audit quality, the perceived contributions of all audit firms—local and foreign—are equal. It also adds to the importance of using AI and how it will enhance the quality of firms and reduce any act of fraud. Lastly, it recommends that firms contribute to training employees on using AI to face and compete with the changes and challenges happening around the world.

Xenophobia in Juror Decision-Making

Abstract With the upsurge of anti-globalizing ideologies and politics, the increasing institutionalization of xenophobia within the legal system has emerged as a pressing concern. Existing law and social science research has underexplored xenophobic bias in the US legal system. This article conceptualizes xenophobic bias as consisting of racism and nationalism. It investigates whether mock jurors reach different verdicts on defendant companies from foreign countries of origin (Japan, France, and China) compared to domestic (US) companies. Using a test simulating a patent lawsuit, the research finds no evidence of general xenophobic bias in juror liability verdict decisions, yet there is a specific bias against the Chinese company when granting damage awards. The similarity-leniency effect that has been established in the previous literature is corroborated in this article. Additionally, political views moderate the effects of the company’s country of origin on juror decisions. This research offers a more nuanced conceptual framework of xenophobic bias in juror decision-making for future law and social science research and informs judicial policies seeking to improve jury instructions and jury selection to reduce xenophobic bias.

A-096 A New Direct Bilirubin (DBIL) Assay with Enhanced Performance in Anti-hemolysis Interference on Mindray BS-2800M Analyzer

Abstract Background Serum bilirubin could be used to assess liver functions. Due to clinical importance, it is highly desired to have an accurate bilirubin test. However, there are circumstances where error could occur in bilirubin test results. In particular, the hemolysis interference is one of the major problems that could mislead the direct bilirubin results because of their relatively high occurring frequencies in the clinical laboratories. To resolve this issue and improve the accuracy for the direct bilirubin, we developed a new reagent formulation for DBIL assay that minimizes hemolysis interference. In addition, this reagent also shown good performance characteristics on Mindray BS-2800M Clinical Chemistry analyzer. Methods The new DBIL assay is a vanadate-oxidation method that bilirubin is gradually transformed to biliverdin because of oxidizing agent vanadate, resulting in decreasing of absorbance at 450 nm. Two-level calibration is used for this assay. DBIL concentrations are obtained from the calibration line with signals from the patient samples in the assay. Following CLSI protocols, basic assay performances were evaluated: interference, precision, linearity, method comparison and low end detection (LOB, LOD, LOQ). Results Hemolysis interference was tested in parallel with DBIL reagents from different IVD companies, Roche, Wako and Chinese domestic main-player companies, A, B, and C. The results showed that the reagents of A and B companies were significantly suffered from hemolysis interference with maximum bias exceeded -30%. Although there are some effects on the anti-hemolysis with DBIL reagents of Wako and C company, the DBIL reagent of Mindray was the best with less than -8% of impact when hemolysate hemoglobin was up to 1000 mg/dL (H index). The Diazo DBIL assay from Roche shown issue with hemolysis interference. The interference to our new DBIL assay from lipid (up to 1000 mg/dL) and ascorbic acid (up to 30 mg/dL) were also with less than ±10% impact. The precision study was run according to EP05A3 with two commercial controls (∼ 10 and 30 µmol/L) and three serum sample pools (∼ 6.8,17.1 and 342 µmol/L). The CVs of repeatability were ranged from 0.54% to 0.58% for controls and 0.24% to 0.88% for serum pools, respectively. The within-lab precision was below 2.5%. The analytical linearity was determined as from 0.66 µmol/L to 439.66 µmol/L. For low-end detection, the LOB, LOD and LOQ were 0.5,1.0 and 1.7 µmol/L, respectively. In addition, the Mindray (y) correlated well with the DBIL assay of Wako (x) reagent on Mindray BS-2800M system (y): y =0.9847 x+0.1301 (r =0.9997, n =400, sample range: 1.08 - 430.00 μmol/L). Conclusions The new Mindray direct bilirubin assay shown a good anti-hemolysis interference performance on BS-2800M system and demonstrated good performances in other assay characteristics. It is therefore suitable for use in clinical laboratories.

Research on the meteorological data transmission system of civil aircraft based on BeiDou satellite

Abstract With the official opening of the Beidou-3 global satellite navigation system, Beidou has entered a new era of global services, extending its service area to the whole world. With the advantages of sufficient data volume and high data security, the BeiDou-3 short message satellite communication system can provide global communication services for airlines, realize two-way data transmission between air and land, and effectively reduce the operating costs of airline companies. Aiming at the demand for low-cost civil aircraft weather data transmission proposed by domestic and foreign airline companies, the current development of civil aviation weather information transmission and the current application status of BeiDou in civil aviation were studied, and the BeiDou satellite-based civil aircraft weather data transmission system was designed. The system architecture, detailed functions and data transmission workflow were analyzed, and the message coding structure was designed using bit-based coding technology. Finally, the feasibility of the scheme is verified through the data demand analysis of weather news and the onboard flight test on a domestic aircraft. The results show that t-he BeiDou short message function has the ability to realize the weather data transmission of a civilian aircraft.

Industrial Policy and Democratic Corporate Governance: Perspectives from the BNDES Case

In the early twenty-first century, Brazil underwent a remarkable economic boom, primarily driven by the Brazilian National Bank of Economic and Social Development (BNDES). This state-owned financial institution spearheaded a new industrial strategy, sponsoring domestic companies, such as Odebrecht and JBS, to their internationalisation. Nevertheless, this initial successful story took a dramatic turn. Over the years, the Brazilian national champions found themselves involved in corruption scandals, human rights violations and environmental damage, with BNDES indirectly funding these activities. This article seeks to discuss this crony capitalism arrangement, examining the role of corporate governance in safeguarding industrial policy from capture. We conclude by exploring how a democratic model of corporate governance could provide some insights for addressing this issue.

The non-alcoholic fruit beverage market through patent prospecting

Non-alcoholic fruit beverages hold significant importance in the fruit processing chain. This article aimed to conduct a technological prospective study, through patents, in this specific beverage area. Patents were searched in the online databases of INPI (Brazil) and EPO (Europe), using keywords, the internation classification number, and filing dates. A total of 80 patents were retrieved, excluding duplicates and out of scope ones. The year 2020 witnessed the highest number of filings, followed by a decrease in subsequent years. Japan held 46% of the patents considered in this study, while Brazil accounted for 26%. Overall, the primary filers are from the industry, while 48% of Brazilian patents had educational and research institutions as filers. Lemon, orange, and grapefruit were the most cited fruits in the analyzed documents, indicating a wide participation of tropical fruits in beverage production. Despite Brazil being one of the world's largest fruit producers, Japan leads in innovations related to fruit beverages. Brazil needs to improve its innovation ecosystem to encourage domestic companies, achieve greater competitiveness in international trade, and add higher value to its traded goods.

THEORETICAL BASIS OF THE FORMATION AND DEVELOPMENT OF GREEN BUILDING

Green construction is a key element of Ukraine's sustainable development, as it contributes to reducing the impact on the environment and increasing the energy efficiency of buildings, which is critically important in the face of global climate change and modern challenges. Green construction also supports Ukraine's integration into the international economy through the implementation of environmental standards, which increases the competitiveness of domestic companies. The purpose of the article is to single out the theoretical basis of the formation and development of green construction, as well as to determine the main problems in this field in Ukraine and ways to solve them. The analysis of Ukrainian and foreign studies have showed that the development of green construction in Ukraine has significant potential, especially under the condition of effective implementation of international standards and their adaptation to local realities, which will contribute not only to the preservation of the environment, but also to economic development, improving the quality of life and health population. The theoretical basis of the formation and development of green construction is systematized. The legislative and regulatory framework for green construction aimed at supporting ecologically sustainable development and construction in Ukraine has been analyzed. The main problems faced by green construction on the way to its development in Ukraine (insufficient regulatory framework, high cost of implementing ecological technologies, low level of public awareness and environmental culture, lack of qualified specialists, technical limitations and infrastructure challenges) are identified, and also given possible solutions to these problems. It is noted that for the further development of green construction, it is necessary to implement comprehensive strategies, which include stimulating investments in the green sector, developing and implementing new technologies, raising quality standards, and promoting environmental education. It is emphasized that government support through financial instruments, such as tax incentives and subsidies, can also contribute to increasing the number of green buildings.

MODELLING GROWTH STRATEGIES OF TRANSPORT ENTERPRISES IN THE CONDITIONS OF CONTEXT UNCERTAINTY

Modern military conditions and tasks of post-war reconstruction require the development of effective strategies for the activity of transport enterprises of Ukraine to ensure the continuity of supplies of military and humanitarian goods. The purpose of the research was to create a model for the selection of optimal strategies for the development of transport enterprises of Ukraine in the conditions of uncertainty caused by the simultaneous influence of military aggression and the deepening of transport integration of Ukraine with the EU. The Saaty's method was selected for the study, which is based on the construction of fuzzy functions and is the most relevant in the context of the influence of a significant number of unstable exogenous and endogenous factors on the functioning of enterprises. In consideration of the evolving landscape of transportation in the European Union and Ukraine, the authors have distilled the overarching objectives of sustainable transportation development (economic, social, and environmental) into eighteen sub-objectives pertaining to the advancement of enterprises. These objectives are then subjected to expert evaluation. The article presents the findings of this expert ranking exercise, delineating the priorities for transportation enterprises in Ukraine across two distinct periods: the current state of martial law and the subsequent phase of post-war reconstruction. The authors have built a model for selecting optimal strategies for the development of a transport enterprise on the basis of a multi-level hierarchy of priority growth goals in two periods. As strategic alternatives, the authors have chosen the "strategy of limited growth"; "strategy of concentrated growth"; "strategy of diversified growth"; "strategy of integrated growth"; and "combined strategy". The paper determines that the appropriate growth strategies for transport enterprises during the period of martial law would be: a strategy of limited growth (rank 1.827) and a combined strategy (rank 2.0980). In the period of post-war reconstruction, the following growth strategies will be appropriate for implementation: concentrated growth (rank 3.0151) and integrated growth (rank 2.6783). The publication proposes a set of possible options for practical management actions in various functional areas of the transport enterprise (financial, organisational, marketing, social, technological, environmental) in accordance with the defined development strategies under martial law and post-war reconstruction. The practical application of the methodological approach to strategic management of transport enterprises in the context of economic uncertainty developed in the article will help to preserve domestic transport companies in the conditions of war and increase their competitiveness in the post-war period. The comprehensive implementation of the identified strategies will contribute to the development of innovative technologies, as well as European social and environmental transport standards in Ukraine.

Fast food investment in Barbados: the experience of McDonald’s

Learning outcomes Specific teaching and learning objectives include to identify factors influencing market expansion decisions and recommend appropriate entry modes, understand factors in the international business environment that contribute to success or failure of international businesses in developing countries, evaluate strategies enabling international businesses to sustain market presence in developing countries and overcome local competition, analyze the concept of local responsiveness in international business operations and suggest strategies for internationalizing domestic companies from developing countries. Case overview/synopsis The McDonald’s case examines the challenges associated with market expansion by global brands. The case occurs during the early-globalization era in the 1990s. Barbados, a developing country, is the site for potential expansion. Prospective investors, the Winters, are desirous of establishing a McDonald’s in Barbados. They need to thoroughly analyze the previous experience of McDonald’s against the host country’s current international business environment, e.g. political, economic, cultural and competitive environment. This case analysis provides a framework for understanding the multifaceted reasons behind McDonald’s exit from Barbados, considering the complex interplay of political, economic, sociocultural, technological and legal factors in the international business environment. The case equips the instructor and students to explore the risks of international expansion, particularly in developing country markets. The case study on McDonald’s failure in Barbados highlights the need to thoroughly examine one’s market entry strategy and available information on the host market and be more locally responsive regarding tastes and preferences. The case study also presents essential lessons for firms and planners from developing countries. Local firms innovated and enhanced their operations in response to the threat from the entry of the global fast-food giant. Yet, they did not seek to internationalize once McDonald’s exited the Barbadian market. The case study, therefore, considers strategies firms from developing countries could utilize to penetrate markets from developed countries. Complexity academic level At the undergraduate level, the McDonald’s Barbados case can be used in international business classes to highlight risks in the international business environment and the need for a carefully planned and executed market entry strategy. Supplementary materials Teaching notes are available for educators only. Subject code CSS5: International Business.

Changing Consumer Preferences in the Prefabricated Housing Sector in Hungary: Construction Companies' Experiences and Statistical Data on Consumer Behaviour

The study aims to explore the consumer behaviour of prefabricated house owners, by analysing the insights of 12 managers of domestic construction companies in Hungary. These interviews reveal consumer behaviour and value considerations in purchasing decisions. The study’s strength lies in the relevance of the interviewed firms, representing 20.45% of production value in domestic single-family housing construction in 2022, according to the Central Statistical Office. Data from three housing-related censuses further complements the interview findings. Despite the ecological advantages of technology, the surveyed consumers are characterised as self-conscious, prioritising self-interest factors such as price, speed, predictability, reliability, and low maintenance costs in their choices. The research also indicates that consumer resistance to the concept of prefabricated housing is diminishing, something that is most likely to be due to generational shifts.

ПРЕДУПРЕЖДЕНИЕ УТОМЛЕНИЯ ПЕРСОНАЛА КАК ИНСТРУМЕНТ WELL-BEING ПРОГРАММ

The article considers the actual problem of modern companies’ activities — the prevention of fatigue and maintaining optimal employee performance. Research data on factors affecting performance are presented, the consequences of workaholism are disclosed and possible methods of combating fatigue and overwork in the workplace are described. An interesting and important experience of domestic and foreign companies in maintaining high staff productivity is described. In particular, organizational measures are indicated (hybrid work schedule; optimization of work regime; rehabilitation measures from companies, etc.), as well as measures for individual prevention of fatigue. The whole set of measures to maintain efficiency, which should be undertaken by the management of companies within the framework of caring for the well-being of their employees, including digital technologies, is considered.

패션산업의 ESG 법적규제와 경영현황에 대한 한국과 유럽연합 비교 연구

The purposes of this study are to compare Environment·Social·Governance(hence, ESG)-related regulations between the EU and South Korea affecting the domestic fashion industry, and to suggest a method for optimizing ESG management of domestic fashion companies by comparing the characteristics with ESG strategies of the EU and South Korean fashion companies. To achieve the purposes, a scoping review was implemented in terms of Arksey & O'Malley (2005)'s procedure. The findings are as follows: 1) The current Korea's sustainability disclosure guidelines are not systematically established compared to the EU. 2) Korea has not been legislated on sustainability disclosures. 3) There are some inadequate parts in the ESG sustainability management reports of domestic fashion companies. 4) ESG practice cases and risk response strategies of domestic fashion companies are being superficially dealt with. 5) ESG management strategies should be derived and integrated more systematically. 6) Objective ESG indicators are needed to introduce an integrated ESG management strategy. From the findings, it was suggested that Korea should quickly come up with effective and specific measures so that fashion companies can respond quickly to the ESG paradigm by preparing ESG-related policies and regulations.

기업가적 지향성과 경영성과 간 관계: 기업 수명주기 단계별 차이 분석

This study empirically analyzes the impact of the managerial environment, CEO's vision and strategy, and organizational management system on entrepreneurial orientation in domestic companies, as well as the relationship between entrepreneurial orientation and business performance. Additionally, it examines how these relationships differ across various stages of the corporate life cycle. The analysis utilizes data from the 2022 Entrepreneurial Activity Survey (Company Edition) conducted by the Korea Youth Entrepreneurship Foundation, designated as official statistics by Statistics Korea, which surveyed 3,120 companies. The results of the empirical analysis are as follows First, business environment, vision and strategy are significantly positively related to entrepreneurial orientation. In terms of firm life cycle, we find that firms in the start-up phase are slightly more sensitive to the business environment, while vision and strategy are important regardless of firm life cycle. Second, the operating system of the firm does not have a statistically significant effect on entrepreneurial orientation, and the hypothesis is rejected. It seems that it is important to have an operating system in place from the start-up stage in terms of the business life cycle. Third, a significant positive relationship was found between entrepreneurial orientation and managerial performance, and entrepreneurial orientation had a positive impact on managerial performance regardless of the firm's life cycle. The results of this study expand the factors influencing entrepreneurial orientation and provide theoretical and policy insights by analyzing the corporate life cycle, which is rarely addressed in the field of entrepreneurship, by distinguishing between the startup phase and other phases.

Issues of LNG producing companies entering the eastern markets and ways to overcome them

This article is devoted to identifying the features of the еastern liquefied natural gas (hereinafter referred to as LNG) markets and new opportunities for entering them. The purpose of this article is to study the problems of LNG producing companies entering the еastern markets and ways to overcome them. The work analyses the current state of the еastern LNG markets and their development prospects, existing barriers, including those caused by the conflict in the Middle East, and possible consequences of the escalation of the conflict. The authors consider the issues of developing localised infrastructure and technological solutions that increase the efficiency of supply chains, meet specific market needs and provide a competitive advantage in the еastern markets. Logframe and comparative analysis, systems approach, and modelling have been used in the research process. As a result, the study has identified a number of challenges for LNG producers, primarily related to geopolitical complexities, regulatory environment, and market development dynamics, to innovations, ecological norms, and understanding regional tensions that may impact supply chains and trade agreements. The findings of the article can be used when domestic companies develop strategies to enter the еastern LNG markets with existing contracts or expand them.

Prosedur Jasa Pengiriman Barang pada PT. Wahana Prestasi Logistik

Freight forwarding services do have an important role in economic growth, especially in freight transport using airplanes. Transportation that is getting better and developing rapidly and supported by the advancement of science and technology today, many domestic freight forwarding companies are also established. Where a company sends the goods in its handling in addition to using sophisticated facilities and infrastructure, the company also needs cooperation with other parties to expand the network and performance system of the company to be better in its handling. Therefore, there is also a lot of competition between companies in the field of freight forwarding services in selling their products to consumers, but not everyone can build a freight forwarding company properly, because to place a company in the domestic freight forwarding industry must be able to have professional human resources, and high work standard capabilities, if they want to get the best access to the market and trust from consumers. This development has caused many problems that must be immediately addressed by freight forwarding companies in order to maintain their business, especially to increase revenue in the sales function. Such conditions have caused companies to work hard to capture the market, through a coordinated organizational structure, high specialization, and the ability of management to work effectively and efficiently.