Cancer and its treatments impose substantial physical and psychological burdens on patients, underscoring the need for innovative and holistic interventions. This narrative review explores the evolving role of clownselling in paediatric and adult cancer care, tracing its historical progression from entertainment to a therapeutic modality. Recognizing the potential of clowning therapy to address emotional, psychological, and existential challenges, the review systematically assesses its impact on treatment adherence, quality of life, and contributions in palliative care settings. By elucidating the therapeutic process, principles, and goals, it provides a comprehensive understanding of the foundations of clowning therapy. Given its positive influence on well-being, the integration of clowning therapy into interdisciplinary care teams and institutional policies is advocated. Future directions include diversified research, technology integration, standardized protocols and awareness campaigns, ensuring the sustained evolution of clowning therapy in fostering holistic well-being within the intricate tapestry of cancer care.
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