To compare the safety and continuous glucose monitoring (CGM) metrics during aerobic exercise (AE) of using temporary target (TT) versus (vs.) suspension of insulin infusion (SII) in adults with type 1 diabetes (T1D) using advanced hybrid closed-loop systems. Randomized crossover clinical trial. Two moderate-intensity AE sessions were performed, one with TT and one with SII. Hypoglycemic events and CGM metrics were analyzed during the immediate (baseline and 59 minutes), early (60 minutes to 6 hours), and late (6 to 36 hours) post-exercise phases. 33 patients were analyzed (44.6±13.8 years, 52% male, time in range (%TIR 70-180 mg/dL) 79.4 ± 12%, time below range (%TBR) <70 and <54 mg/dL was 1.8±1.7% and 0.5±0.9%, respectively). Differences were found between TT vs. SII use in the early phase for %TIR 70-180 mg/dL (83.0 vs. 65.3,p=0.005), time in tight range (%TITR 70-140mg/dL) (56.3 vs. 41.5,p=0.04) and time above range (%TAR>180mg/dL) (15.3 vs. 31.8,p=0.01). No significant differences were found in the CGM metrics during the different phases of physical activity. When evaluating the diurnal period, %TIR was higher for TT use (82.1 vs. 73.1,p=0.02) and %TAR was higher for SII (15.0 vs. 22.96,p=0.04), with no difference in the number of hypoglycemic events or changes in time below range (%TBR) <70 and <54 mg/dL. The use of TT compared to SII is equally safe in the immediate, early and late phases of AE. However, the use of TT allows a better glycemic profile to be achieved in the early phase of exercise.