Distress In Young Adults Research Articles

Contrast Avoidance and Anxiety Sensitivity Mediate the Relationship Between Childhood Maltreatment and Psychological Distress in Young Adulthood.

Childhood maltreatment (CM) is associated with elevated depression and anxiety in young adulthood; however, there is a dearth of research identifying the intermediary pathways that link CM to these phenomena. The present study investigated two psychological factors-contrast avoidance, sensitivity to and avoidance of sudden negative emotional shifts, and anxiety sensitivity, the fear of arousal-related body sensations-as potential mediators of the relationship between CM and psychological distress in young adulthood. Our sample consisted of 280 undergraduate students who completed self-report measures of childhood maltreatment, anxiety sensitivity, contrast avoidance (i.e., the Contrast Avoidance Questionnaire), and psychological distress. We constructed a series of parallel mediation models to test whether contrast avoidance and anxiety sensitivity mediate the relationships between child maltreatment and psychological distress. CM was related to anxiety and stress indirectly through both contrast avoidance and anxiety sensitivity but was related to depression only through contrast avoidance. There were no significant differences in the magnitude of the indirect effects between contrast avoidance and anxiety sensitivity for the models predicting anxiety and stress. Contrast avoidance and anxiety sensitivity both appear to play important roles in understanding how early experiences of CM relate to psychological distress in young adulthood. Theoretical and clinical implications are discussed.

Association of Obesity With Psychological Distress in Young Adults: Patterns by Sex and Race or Ethnicity

BackgroundRecent studies have emphasized the intricate relationship between obesity and psychological distress, unraveling the complex interplay of biological, psychological, and sociocultural factors. However, a conspicuous knowledge gap persists in understanding the association between obesity severity and psychological distress, particularly in young adults, marked by limited empirical data. ObjectivesThis study comprehensively investigates the link between obesity and psychological distress among young adults, emphasizing potential variations based on gender and race or ethnicity. Addressing this gap is crucial for informing targeted interventions and understanding the nuanced impact of obesity on mental health in this demographic. MethodsUtilizing data from the 2013 to 2018 National Health Interview Survey, individuals aged 18 to 26 years were analyzed. Body mass index served as the primary exposure variable, with the Kessler Psychological Distress Scale assessing the primary outcome. Fully-adjusted ordinal regression models were employed for analyses. ResultsAmong the 20,954 participants included in this study, representing 35,564,990 adults, 27% were overweight and 24% had obesity. In class III obesity, individuals experienced 1.4 times more psychological distress than those with normal weight (OR: 1.393; 95% CI: 1.181-1.644; P < 0.001). Subgroup analyses revealed consistent trends in non-Hispanic White (OR: 1.615; 95% CI: 1.283-2.032; P < 0.001) and female participants (OR: 1.408; 95% CI: 1.408-2.096; P < 0.001). ConclusionsThis study underscores the association between obesity and psychological distress in young adults, notably impacting non-Hispanic White and female populations. The findings bear significant implications for shaping future health policies, addressing the mental health crisis, and mitigating the increasing prevalence of obesity among young U.S. adults.

THE RELATIONSHIP OF PHUBBING, EMOTIONAL INTELLIGENCE AND PSYCHOLOGICAL DISTRESS IN YOUTH

Objectives: The purpose of this study was to investigate the relationship between phubbing behavior, emotional intelligence, and psychological distress in youth and the predicting role of phubbing and emotional intelligence in determining psychological distress in youth. Research Design: Correlational research design was used. Place And Duration of Study: This study was conducted between March 2022 to February 2023 at Department of Applied Psychology, University of Management and Technology Lahore. Subjects and Methods: A total of 200 university students aged between 18 and 26 (M =21.36; SD =1.94) were selected from different public and private sector universities of Lahore through convenient sampling technique. The Phubbing Scale,54 Wong and Law Emotional Intelligence Scale,55 and Depression, Anxiety and Stress Scale 2156 along with self-constructed demographic sheet were used to collect data. Results: The results revealed a positive relationship between phubbing and psychological distress in young adults. Further, phubbing was found to be a significant predictor of psychological distress in young adults, however Overall emotional intelligence did not predict it. Further, no significant gender differences were found in phubbing, emotional intelligence, and psychological distress. Conclusion: The study highlights the impact of excessive mobile usage on emotional intelligence and psychological distress levels and may help in proposing interventions to reduce phubbing and improve emotional intelligence as potential solutions to mitigate psychological distress.

Resilience and Psychological Distress in Early Adulthood with Non-Suicidal Self-Injury: A Scoping Review

According to Orenstein &amp; Lewis (2021), young adults are at a transitional age and have demands on developmental tasks. When these demands are not met, it can cause feelings of suffering, activities that become obstacles and characterized by symptoms of anxiety and depression or called psychological disorders (Kalia &amp; Knauft, 2020; Dharma et al, 2020). Psychological distress that are not balanced with adaptive problem solving can cause maladaptive distress, it called non-suicidal self-injury (Rahmasari, 2021). According to Hans et al (2022) bounce back is needed in young adults, so they can face the problem, or it called resilience. In the previous study by Khan &amp; Ungar (2021), there were limited matters such as the search for coping strategies carried out by the sample in the study and protective factors from the emergence of self-harm and the non-specific definition of NSSI. Aims:identification research on resilience and psychological distress in young adults with NSSI. Method:scoping review. Result: 10 journals that met the inclusion criteria were selected. Hypothesis of this study is the results of the study indicate that the conditions of psychological distress in young adults with NSSI have low resilience and high levels of psychological distress. The benefits of this research theoretically are to enrich scientific references in the field of clinical psychology, especially regarding resilience and psychological disorders in young adults with NSSI and practically this research can be continued by taking into account several limitations and can be developed into interventions for young adults with NSSI.

Scrolling and Stress: Exploring Internet Usage for Social Media and Psychological Distress in Young Adults

Abstract Background: Internet usage is increasing significantly among young adults for various purposes. Understanding the extent of their social media engagement is crucial. This study aims to explore how much young adults use the Internet for social media and its link to psychological distress. Methods: The study included 423 UG and PG students from two private colleges in Ooty, Tamil Nadu. They were selected using a purposive sampling technique. An online survey collected data through a sociodemographic data sheet, the Internet Use Scale, and the Kessler 10 Psychological Distress Scale. Results: The findings revealed that 26% (n = 111) of students excessively use the Internet for social media activities. More males (56.76%) than females (43.24%) use this excessively. Around 23% of these heavy users have four or more social media accounts. Instagram is the most popular platform (32%), followed by combinations such as Instagram, Snapchat, and YouTube (28%), and Instagram paired with YouTube (20%). Excessive Internet users (P &lt; 0.001) spend an average of 3.57 h on social media, while nonexcessive users spend 2.51 h. Over half of the excessive users had psychological distress (P &lt; 0.001). Significant positive correlations were found between average social media usage hours, Internet use score, and psychological distress (P &lt; 0.001). Conclusion: Internet usage for social media activity is rising among students, and using multiple social media accounts and excessive use are associated with psychological distress.

Factors contributing to financial distress in young adults with cancer: Material resources, health, and workplace.

Financial distress is a primary concern for young adults with cancer. The aim of this study was to identify material resources, physical and psychological health, and workplace variables that are associated with financial distress in young adult cancer survivors. A cross-sectional study was conducted using the Cancer Survivor Employment Needs Survey. Participants were young adults (18-39 years of age) who lived in the United States and had a cancer diagnosis. Multivariable linear regression was used to model relations between financial distress and material resources, physical and psychological health, and workplace variables. Participants (N = 214) were mostly non-Hispanic White (78%), female (79%), and had a mean age of 31 years and 4.6 years post-diagnosis. Material resources, physical and psychological health, and workplace variables were all identified as contributing to study participants' financial distress. Among the young adults surveyed, financial distress was prevalent, and an array of problems were associated with financial distress. Oncology and rehabilitation providers should openly discuss finances with YAs with cancer and guide them to resources that can address their financial, benefits, and vocational needs to ultimately improve quality of life.

Long COVID and psychological distress in young adults: Potential protective effect of a prior mental health diagnosis

BackgroundAlthough young adulthood is a period characterized by marked psychological vulnerability, young adults are typically considered to be in good physical health and are therefore understudied with respect to the effects of COVID-19 infection and long COVID. The present study examined associations between post-acute sequelae of COVID-19 (PASC) and serious psychological distress during young adulthood, and tested whether prior mental health diagnosis moderated this association. MethodsParticipants were 44,652 young adults who completed the Spring 2022 administration of the American College Health Association-National College Health Assessment III (ACHA-NCHA). Blockwise logistic regressions tested the odds of meeting the clinical threshold for serious psychological distress. ResultsPASC was associated with 53 % increased likelihood of meeting the clinical threshold for serious psychological distress. Among young adults with a prior mental health diagnosis, PASC predicted 36 % increased odds of serious psychological distress; among those without a diagnosis, PASC predicted 81 % increased odds. LimitationsPASC was assessed using a single self-report item rather than a clinical diagnosis of specific symptomatology. The analyses were cross-sectional and relied on concurrent reports of PASC and psychological distress which precluded us from making claims regarding directionality of the associations. The outcome of generalized psychological distress limited us from generating targeted treatment recommendations. ConclusionsPASC may confer elevated psychological distress among young adults. The association of PASC to serious psychological distress was stronger in young adults without a mental health diagnosis than those with a diagnosis. Prior experience with mental illness may mitigate the psychological burden of long-term symptomatology.

The Effectiveness of Intergenerational Communication-Based Intervention to Reduce Psychological Distress in Young Adults Experiencing Conflict Related to Marriage Plans

The Effectiveness of Intergenerational Communication-Based Intervention to Reduce Psychological Distress in Young Adults Experiencing Conflict Related to Marriage Plans

Relationship of Temporomandibular Joint Disorders and Psychological Distress in Young Adults

Background: Temporomandibular disorders (TMD) relate to dysfunctions that impact the temporomandibular joint (TMJ), masticatory muscles, and connected structures. Psychological well-being can be among the various factors that TMD affects. Prior studies conducted in different countries have demonstrated a correlation between TMD symptoms and psychological distress in young adults. However, research on this topic is limited in Indonesia. Objective: To assess the association of symptoms of temporomandibular joint disorder and psychological stress in young adults. Materials and Methods: This research employed an analytical cross-sectional design and involved 354 participants (141 males and 213 females) aged 19-21 from Kampus A of Universitas Trisakti. The subjects' general characteristics, including gender, age, and ethnicity, were described. The data were gathered through two types of questionnaires: DC/TMD axis I (Symptom Questionnaire) and axis II (Patient Health Questionaire-PHQ-4), and were analyzed using the Spearman correlation test administered through Google Form. Result: The study's findings revealed that 141 participants (39.8%) were male, while 213 (60.2%) were female. Among the research subjects, 91 individuals - 32 males and 59 females - experienced the most discomfort in the pain category, with the mean PHQ-4 score for pain being the highest at 4.68. The bivariate analysis demonstrated a moderate correlation coefficient value (r = 0.401) and a significant relationship (p 0.05) between temporomandibular disorders (TMD) in the pain category and psychological distress. The prevalence of TMD was 39.8% in males and 60.2% in females. Conclusions: TMD is a common problem among young adults aged 19-21 years, and pain associated with TMD can lead to psychological distress in this age group.

Evaluating the effect of COVID-19 pandemic on the psychological health of young adults in India

COVID-19 pandemic has affected the mental health of individuals, particularly young adults. Using the ‘strength and difficulty questionnaire 17&lt;sup&gt;+&lt;/sup&gt; extended version’, we studied the severity of psychological problems and the resultant distress in young adults; the relationship between the ‘difficulty’ and ‘impact’ scores; and the effect of distress in terms of a number of day-to-day activities affected during a pandemic. Data was collected from 743 college/university students (December 2020-February 2021) in India. Descriptive, relative frequencies, and nonparametric tests are applied here. Females were facing more psychological behavioral problems as compared to males as the&lt;em&gt; &lt;/em&gt;p-value is less than 0.001. Males with age&amp;lt;20 years were least affected by COVID-19. Day-to-day activities are affected by almost 45% of young adults because of distress. ‘difficulty’ and ‘impact’ severity bands were significantly different from the previous standard proportions. No significant association was there between ‘difficulty’ and ‘impact’ scores (p-value&amp;lt;0.001). 53% of those contracting COVID-19 had severe distress as against 45% of those who did not. 46% of the respondents were in the ‘abnormal’ category and 59 out of 327 were facing ’a great deal’ problems in more than two areas.

Childhood food insecurity, mental distress in young adulthood and the supplemental nutrition assistance program

Food insecurity affects 14% of US homes with children and has been associated with increased mental health problems. Few studies have examined long-term consequences for mental health and the role of social policies. This study examined the association between childhood household food insecurity (HHFI) and young adult psychological distress, and the moderating role of caregiver psychological distress and the Supplemental Nutrition Assistance Program (SNAP) using data from the Panel Study of Income Dynamics (1995–2015). The sample comprised 2782 children ages 0–12 years in 1997. Past-year HHFI was measured using the USDA 18-item questionnaire in 1997, 1999, 2001 and 2003. Young adults' non-specific psychological distress was measured with the Kessler (K6) scale in 2005, 2007, 2009, 2011, 2013 and 2015. Three trajectories of food insecurity were identified: 1) Persistent food security (70.5%); 2) Intermediate/fluctuating food insecurity (24.6%), and; 3) Persistent food insecurity (4.9%). Compared to persistent food security, fluctuating and persistent food insecurity were associated with significantly higher levels of psychological distress. This association was robust to adjusting for socio-demographic factors, caregiver psychological distress, and family access to governmental supports: [Adj. ORs (95% CI's = 1.72 (1.59–1.85) and 2.06 (1.81–2.33)]. Having a caregiver who suffered from psychological distress (1997 and/or 2002) and growing up with persistent food insecurity placed children at greater risk for mental health problems. Access to SNAP attenuated this risk. Early HHFI is associated with psychological distress in young adulthood. Interventions to increase access to SNAP and address caregivers mental health may prevent mental health problems associated with childhood HHFI.

Psychosocial distress in young adults surviving hematological malignancies: a pilot study

PurposeSurvivors of cancer during young adulthood face multiple psychosocial challenges following treatment. This study explores psychosocial distress and unmet needs among young adult survivors treated of hematological malignancies.MethodsA total of 85 young adults aged between 18 and 39 years at time of diagnosis, were invited to join the survey after the completion of treatment with curative intent. Sociodemographic data and the need for advice were gathered with a self-report questionnaire. A set of standardized questionnaires for quality of life (EORTC QLQ-C30), psychosocial stressors (PHQ-S), fear of progression (PA-F-KF), cancer-related fatigue (EORTC QLQ-FA12), and symptoms of anxiety (GAD-7) or depression (PHQ-9) was employed. Descriptive statistics and multivariate analysis were conducted.ResultsForty-seven young adult cancer survivors responded. A quarter of patients (26%) reported depressive symptoms, 15% suffered from anxiety, 36% from fear of progression, and 21% reported increased psychosocial stressors. They had a lower QoL than the general population and reported poorer outcomes on all single-item and multi-symptom scales. Employment was significantly associated with lower levels of psychosocial distress, anxiety, fatigue, and better QoL.ConclusionYoung adult cancer survivors exhibited a high disposition for psychosocial distress. They reported excessive demands in everyday life and resumption of work. However, a longitudinal study of young adult cancer survivors is needed to confirm the results of this pilot study. In future, psycho-oncological and social support need to become an inherent part of the aftercare of survivors of young adult cancer survivors.

The Relationship of Adverse Childhood Experiences and Emotional Distress in Young Adults.

Emerging evidence notes increased depression, anxiety, and stress among the general population during the COVID-19 pandemic. However, little is known about populations at increased risk for emotional distress as the pandemic continues. Persons with adverse childhood experiences (ACE) are one group that may be at higher risk for emotional distress. The aim of this study is to examine whether young adults, particularly Black young adults, with histories of ACEs report more emotional distress during the pandemic than those with no ACE exposure. Using a cross-sectional, quota sampling approach, 100 Black and 100 White young adults were recruited using online sources (e.g., University website, Facebook). Due to the pandemic, participants were screened via Zoom and, if eligible, completed a demographic questionnaire, emotional distress measures (i.e., anxiety, depression, stress), and the ACE Questionnaire online via a Qualtrics survey. Structural equation modeling (SEM) analysis examined the ACE and emotional distress relationship, and multigroup SEM assessed racial differences. High levels of both emotional distress and ACEs were observed. Black young adults reported significantly more ACEs than Whites. ACEs were significantly associated with each measure of emotional distress regardless of race or other covariates. Findings reveal that during the pandemic, persons exposed to ACEs reported greater emotional distress than those with no ACE exposure. Nurses must screen patients for both emotional distress and ACE to target those at higher risk for early intervention and initiate treatment as needed to mitigate long-term mental health consequences.

Patterns of Adverse Childhood Experiences Predict Event-Related Distress in Young Adults Following the 2016 Presidential Election

Adverse childhood experiences (ACEs) and sociopolitical stressors have negative consequences for young adults’ mental health. The current study examined how patterns of ACEs were associated with event-related clinical distress following the 2016 United States presidential election and tested whether difficulties in emotion regulation exacerbated ACE effects in 751 young adults. A latent class analysis (LCA) identified four classes of ACE exposure: Minimal Exposure (55.2%), Moderate Household Dysfunction (21.3%), High Verbal and Physical Abuse (17.8%), and Systemic Exposure (5.6%). Young adults in the Systemic Exposure class reported more event-related intrusion symptoms compared to all other classes. Lower levels of difficulty in emotion regulation were protective for classes with lower ACE exposure but were not relevant for classes with higher ACE exposure. Thus, ACEs may occur in unique constellations that have implications for sociopolitical stressors and mental health outcomes in young adulthood.

Psychological Distress in Young Adults with Acute Myeloid Leukemia Undergoing Induction Chemotherapy.

Young adults (YAs), aged 18-39 years, with acute myeloid leukemia (AML) navigate life disruptions amid an unpredictable illness trajectory. We conducted a secondary analysis of patient-reported outcomes for hospitalized YAs with high-risk AML receiving intensive chemotherapy, collected during a multisite randomized clinical trial. Of the 160 patients, 14 (8.8%) were YAs. At week 2 of hospitalization, YAs demonstrated significant worse quality of life (β = -18.27; p = 0.036), higher anxiety (β = 2.72; p = 0.048), and higher post-traumatic stress disorder (PTSD; β = 10.34; p = 0.007) compared with older adults. Our analysis demonstrated a longitudinal presence of anxiety and PTSD, suggesting persistent unmet psychological needs for YAs with AML.

Psychological Distress as a Predictor for Weight Self-Stigma among Youth in Jazan Region, Saudi Arabia: A Cross-Sectional Survey

Background: Weight-related self-stigma has well-known psychological consequences. There is growing evidence that psychological problems, including depression, anxiety, stress, predict the existence of weight stigma. The purpose of the present survey was to examine the association between weight self-stigma and psychological distress among Saudi young adults in Jazan region.&#x0D; Objectives: The rationale of this study was to investigate the correlation between weight self-stigmatization and psychological distress in young adults In Jazan region, Saudi Arabia.&#x0D; Materials and Methods: We performed a cross-sectional investigation using the wight-self stigma questionnaire (WSSQ) and the depression, anxiety, and stress scale 21 (DASS 21) in a convenience sample of 399 participants. The statistical analysis included descriptive analysis, independent-samples t-test, analysis of variance (ANOVA), and linear regression.&#x0D; Expected Results: We hypothesize that there is correlation between weight self-stigma and psychological distress among young people In Jazan region, Saudi Arabia.&#x0D; Results: The mean age was 21.12 years ± 2.91 years. Stigmatization of oneself weight (both self devaluing and enacted stigmatization concern) was significantly associated with respondents' body mass index (BMI) (p &lt; .001), depression, anxiety, and stress (p &lt; .001). There was a significant correlation between respondents' scores on the WSSQ and DASS 21. The main predictors for weight self-stigma were BMI (p &lt; .001) and psychological distress (p &lt; .001).&#x0D; Conclusion: The study revealed a strong association between weight self-stigma and psychological distress among young adults in Jazan region, Saudi Arabia. Further epidemiological and clinical studies on the national level are warranted.

Internet gaming disorder, aggression and psychological distress in young adults

IntroductionInternet gaming has become a topic of interest since it has positive but also negative effects.ObjectivesTo explore the relationship between internet gaming, aggression and psychological distress in young adults.Methods229 Portuguese subjects (55.5% females), with a mean age of 21.13 years old (SD = 2.075, range: 18-29) filled in the Internet Gaming Disorder Scale-Short Form, the Buss-Perry Aggression Questionnaire, and the Depression, Anxiety and Stress Scales-21.ResultsThe total score of internet gaming was of 15.90 (SD=6.32), 79.9% (n=183) of the sample used to play videogames and 24.5% (n=56) spent more than ten hours playing a week. Internet gaming was correlated with physical aggression (r=.23**), anger (r=.31**) and hostility (r=.35**); and with depression (r=.36**), anxiety (r=.28**), and stress (r=.31**). A Mann Whitney U test revealed significant differences in internet gaming disorder levels of males (Md=130.75, n=102) and females (Md=102.35, n=127), U=4871.000 z=-3.232, p=.001, r=4.49.ConclusionsInternet gaming disorder is associated with aggression and psychological distress, and males presented higher internet gaming disorder levels. Future studies are needed to explore the bidirectional relationships between gaming disorder, aggression and psychological distress.DisclosureNo significant relationships.

594-P: Telehealth Results in Increased Visit Frequency and Lower Diabetes Distress in Young Adults (YA) with Type 1 Diabetes (T1D)

Background: Managing T1D as a YA is challenging due to changing physiology, psychosocial demands, and increasing independence. Fewer than one-third of YA with T1D meet the ADA guidelines of quarterly diabetes visits and only one in seven attain the recommended hemoglobin A1c level of &amp;lt;7%. YA from disadvantaged ethnic, racial, and socioeconomic backgrounds face even greater T1D management obstacles. Methods: The CoYoT1 Care model was adapted for diverse, predominantly publicly insured, YA with T1D at a large urban hospital. A 15-month 4-arm randomized controlled trial collected data on 68 YA, ages 16-25. Participants received either CoYoT1 Care or Standard Care via in-person or Telehealth (TH) , prior to COVID-19; all in-person visits transitioned to TH in March 2020. CoYoT1 Care consists of patient-centered provider visits with bimonthly virtual T1D peer group sessions. Results: YA who attended &amp;gt;50% of study visits by TH attended more visits during the study period (3.4) than those who primarily attended in-person (2.6, p&amp;lt;0.0001) . Those who were seen more by TH also had stable levels of diabetes distress versus increased distress in those attending in-person visits (p=0.02) . A conjoint analysis conducted with YA found that not having to travel to clinic for visits was TH’s greatest benefit; technical problems and not always having private space were its biggest challenges. Participants also rated access to a clinic coordinator and TH visits as extremely valuable. Conclusions: TH was successfully adapted for diverse YA with T1D, resulting in increased attendance and stable diabetes distress compared to in-person care. Participants overwhelmingly indicated that the benefits associated with TH, such as saving time and money traveling and parking, outweighed any technical challenges. Larger studies with longer term follow-up, not occurring during a global pandemic, are needed to refine TH’s role in patient-centered care of YA with T1D. Disclosure J.Raymond: None. J.L.Fogel: None. M.W.Reid: None. E.Salcedo-rodriguez: None. D.Fox: None. E.Pyatak: Research Support; Abbott Diabetes. Funding Donaghue Foundation

Attachment relationships and psychological distress in young adults: The mediating role of self-esteem

• In youth the relationship between attachment and psychological distress is unexplored. • Here, effects of primary and secondary attachment on distress were examined. • Findings show mediation effects of both attachment types through self-esteem. • First empirical evidence for the individual roles of both types of attachment. The relationship between attachment security and psychological distress (such as depressive and anxiety symptoms) is well established. However, the role of attachment security beyond primary attachment, referred to as secondary attachment, and the mechanism underlying this relationship is under-explored among young adults. This study sought to investigate the effects of primary attachment and secondary attachment on psychological distress with self-esteem as a mediator in young adults. Four hundred and fifty two UK participants aged 18–25 (55.76% females; Mean age = 20.72; SD = 2.29) completed measures of attachment, self-esteem and psychological distress. Using two mediation models, we tested the effects of primary attachment and secondary attachment separately on psychological distress mediated by self-esteem, while controlling for the other type of attachment (i.e. primary or secondary). The findings supported the mediation effects of both primary attachment and secondary attachment through self-esteem on psychological distress. This study provides the first empirical evidence for the individual role of primary and secondary attachment relationships through self-esteem, which has important implications for preventive and intervention strategies to lessen psychological distress among young adults.

Diabetes Distress in Young Adults With Youth-Onset Type 2 Diabetes: TODAY2 Study Results.

To assess the prevalence of high diabetes distress and associated factors in the Treatment Options for Type 2 Diabetes in Adolescents and Youth (TODAY2) study cohort of young adults with youth-onset type 2 diabetes. Participants completed the Diabetes Distress Scale (DDS) at end-of-study visits. Factors examined for association with high distress were demographic (sex, race/ethnicity, age, education, income), medical (HbA1c, BMI, complications), psychological (depressive and anxiety symptoms), and social (number in household, offspring, health care coverage, established with diabetes care provider). Univariate logistic regression identified factors associated with high distress that were controlled for in multivariate logistic regressions. Of 438 participants, 66% were female (mean age 26.8 years, 18% non-Hispanic White, 37% non-Hispanic Black, 38% Hispanic). High distress (DDS ≥2) was reported by 105 (24%) participants. Subscales identified 40% with high regimen distress and 29.7% with high emotional burden. A greater percentage of those with high distress were female (P = 0.002), diagnosed with hypertension (P = 0.037) and retinopathy (P = 0.005), treated with insulin, had higher HbA1c, and had moderate to severe depressive and anxiety symptoms (all P < 0.001). In multivariate analyses, female sex (P < 0.001), HbA1c (P < 0.001), anxiety symptoms (P = 0.036), and lack of health care coverage (P = 0.019) were associated with high distress, after controlling for potential confounders. Moderate to severe depressive symptoms were associated with high regimen distress (P = 0.018) and emotional burden (P < 0.001); insulin treatment was associated with high emotional burden (P = 0.027). Future research should identify modifiable factors associated with high diabetes distress in young adults with youth-onset type 2 diabetes that may inform distress interventions with this medically vulnerable group.