Dissolution Of Particles Research Articles

Inter riverine variability in microplastic distribution among two tropical rivers – Chalakudy and Periyar, Southwest India

ABSTRACT The study intends to bridge the lack of baseline information on microplastic (MPs) contamination in two river systems (Periyar: the longest river, lifeline of the Kerala State and Chalakudy: the fifth longest river) and hence is highly relevant. Sampling was carried out twice during December 2020 and January 2021. Elevated level of contamination was recorded at midstream sites in Chalakudy and downstream sites at Periyar. Small-sized particles (<100 µm) constituted the majority (>45%) in both river systems resulting from the disintegration of larger particles or direct release of primary MPs. Prevalence of fragment shape, accounting for ≈48–71% across all sites in both rivers, resulted from the disintegration of meso or macro plastics. Preponderance of blue-coloured particles (≈33–67%) inferred potential risk to aquatic organisms. Low-density polyethylene emerged as the dominant polymer group, originated from packaging materials and bottles. Overall abundance and recovery rate in both rivers indicate that MPs occur at all sites, irrespective of land use patterns, sourced to the degradation of abandoned fishing gears, shipping, tourism activities, and untreated waste disposal. The high risk of microplastic pollution in the study area was endorsed by polymer hazard index and coefficient of microplastic impact index.

Ultrasonic-assisted pre-concentration of iron values in bauxite residue suitable for reduction-roasting purpose

The study aims to explore the feasibility of using low-frequency ultrasonic washing to pre-concentrate iron values in waste bauxite residue (BR) containing 32.60 wt. % iron. This novel approach involves ultrasonication followed by water-washing to pre-concentrate iron before reduction-roasting of BR. Conventional reduction-roasting of BR is more expensive compared to pre-concentrated BR, making this method potentially cost-effective. The process consists of a two-stage ultrasonic treatment procedure. In the first stage, ultrasonication at 30 °C, with 40% solid content (w/v) for 30 min, improves the iron grade to 41.2 wt. % with 82% recovery. However, a second stage of ultrasonication is necessary to further upgrade the iron. The study optimized the ultrasonication time, temperature, solid content (%, w/v), and water washing parameters. Under optimal conditions (ambient temperature, 30% solid content (w/v), 45 min of ultrasonication), the iron grade reached 49.1 wt. % (Fe2O3 70.2) with 66% recovery. Water-washing parameters were found to be less effective compared to ultrasonication parameters. The settling time after water washing significantly affects the grade and recovery of the product. The ultrasonic effect on the BR particle surface leads to the breakage of surface-alkali coating and the disintegration of locked particles to generate free iron and other particles. Particle size analysis supports the disintegration of BR particles into smaller pieces. The physicochemical characterizations of different products were carried out using ICP-OES, XRD, FTIR, and FESEM studies to support the experimental findings. The possible iron separation mechanism is discussed utilizing available literature, as well as experimental and characterization evidence.

Thermal Stability and Thermal Fatigue Resistance Improvement of New High Toughness 5% Cr Hot Working Die Steel

This work developed a new high toughness 5% Cr martensitic hot working die steel (GYDCK-20), which exhibits better thermal stability and thermal fatigue resistance than AISI H13 steel. The concrete study involves: conducting on the evolution of microstructures and mechanical properties of two steels during the 60-hour holding process at 600°C, as well as the thermal fatigue behavior under the cyclic heating-water quenching conditions. The experimental results showed that in the case of ensuring the same initial hardness of two steels (43-43.5 HRC), GYDCK-20 emerged better thermal stability and superior toughness after 60-hour holding process at 600°C. After thermal cycling was increased from 1000 to 2000 times, the average crack length growth rate of GYDCK-20 was 31.8% lower than that of H13 and the maximum crack width growth rate was 35.1% lower than that of H13. It was found that thermal fatigue cracking was dominated by transgranular propagation at lower cycle numbers, while more inclined to propagate along the grain boundaries at higher cycle numbers. The higher toughness of GYDCK-20 steel promotes the dispersion of thermal stress, thereby enhancing the thermal fatigue resistance. It is mainly attributed to the lower V content of GYDCK-20 steel, which reduces the density of large-sized MC primary carbides. On the other hand, the lower Si content promotes the dissolution of cementite particles, and the secondary carbides precipitate in a smaller and uniformly distributed form, which hinders the propagation of thermal fatigue cracks, while also delays the coarsening of the fatigue-adverse phase M23C6 carbides.

Supercritical CO2 assisted bioMOF drug encapsulation and functionalization for delivery with a synergetic therapeutic value

Despite the impressive characteristics of biological metal organic frameworks (bioMOFs) for their use as drug delivery systems (DDs), there are still some parameters related to their structural stability and processing routes that have decelerated their realistic application in this field. Both drawbacks are unraveled in this work for the microporous bioMOF CaSyr-1 by using supercritical CO2 (scCO2) to load the bioMOF with the anti-tubercular isoniazid (INH) drug, and functionalize its external surface with a hydrophobic protective layer of stearate (S). The hydrophobicized CaSyr-1(INH)/S vehicle is further coated with a neutral surfactant (PS60) to enhance the wettability of the system. In vitro tests, related to drug carrier biocompatibility and drug release in body simulated fluids, are performed to demonstrate potential prospective of the designed DDs in pharmacy. The synthetized product displayed total biocompatibility even at high concentrations, and the particle size and dissolution rate showed to be adequate for pulmonary administration.

DEM simulations of particle dissolution effects on the passive earth pressure of retaining walls

Assessing passive earth pressure is fundamental in geotechnical engineering practice. Mineral dissolution in the soil can reduce the soil strength, causing an overestimation of passive earth pressure in design. In this study, the effect of dissolution on passive earth pressure on retaining walls is investigated by using discrete element method, taking into account three modes of motion: translation (mode T), rotation around the wall bottom (mode RB), and rotation around the wall top (mode RT). The simulations show that the particle dissolution results in a significant reduction in the passive earth pressure on retaining walls. The largest reductions of resultant force are about 73.5 % and 78.5 % in modes T and RT when wall displacement is minor. Nevertheless, when the wall displacement is large, the largest reduction in resultant force is approximately 74.7 % in mode RB. A detailed analysis is provided to explain this phenomenon. Dissolution also leads to weak force chains and an increase in soil porosity, thereby weakening wall-soil interactions. Dissolution has a significant effect on passive earth pressure of lower part's soil. This study suggests that reinforcing the lower part's soil and preventing seepage in this area can help mitigate the effects of dissolution on retaining walls.

The Key Role of Wettability and Boundary Layer in Dissolution Rate Test.

The present work proposes a mathematical model able to describe the dissolution of poly-disperse drug spherical particles in a solution (Dissolution Rate Test-DRT). DRT is a pivotal test performed in the pharmaceutical field to qualitatively assess drug bioavailability. The proposed mathematical model relies on the key hallmarks of DRT, such as particle size distribution, solubility, wettability, hydrodynamic conditions in the dissolving liquid of finite dimensions, and possible re-crystallization during the dissolution process. The spherical shape of the drug particles was the only cue simplification applied. Two model drugs were considered to check model robustness: theophylline (both soluble and wettable) and praziquantel (both poorly soluble and wettable). The DRT data analysis within the proposed model allows us to understand that for theophylline, the main resistance to dissolution is due to the boundary layer surrounding drug particles, whereas wettability plays a negligible role. Conversely, the effect of low wettability cannot be neglected for praziquantel. These results are validated by the determination of drug wettability performed while measuring the solid-liquid contact angle on four liquids with decreasing polarities. Moreover, the percentage of drug polarity was determined. The proposed mathematical model confirms the importance of the different physical phenomena leading the dissolution of poly-disperse solid drug particles in a solution. Although a comprehensive mathematical model was proposed and applied, the DRT data of theophylline and praziquantel was successfully fitted by means of just two fitting parameters.

A quasi-in-situ EBSD study on abnormal grain growth in 2219 aluminum alloy friction stir welded joints during post-weld heat treatment

Abnormal grain growth occurs in the friction stir welds of 2219 aluminum alloy during the solution treatment. To further investigate abnormal grain growth, the quasi-in-situ electron backscatter diffraction (EBSD) experiment, including the EBSD testing and heating by thermal simulation testing machine, was proposed to observe the grain growth process in the weld. The results show that the abnormal grain growth behavior in the stir zone and the thermo-mechanically affected zone is different, and different microstructures at different positions in the weld promote the growth of abnormal grains. In the stir zone, the modified Humphreys’ model is used to analyze the abnormal grain growth behavior. The grains with an advantage size and low strain are more likely to grow abnormally. The non-uniform pinning caused by the dissolution of second-phase particles further promotes abnormal grain growth. In the thermo-mechanically affected zone, the abnormal grains are formed by unstrained equiaxed grains near the stir zone or recrystallized sub-grains. The growth of abnormal grains in the thermo-mechanically affected zone is a strain-induced grain boundary migration process. The research is helpful to understand the abnormal grain growth in friction-stir welds during post-weld heat treatment.

The influence of CeO2 on the oxidation resistance of TaC/Ni composites

The in-situ TaC/Ni composites with different CeO2 content (0 wt%, 1 wt%, 2 wt%) were prepared by reactive sintering method, and their oxidation behavior in air at 1073 K was analyzed by static cyclic oxidation method to investigate the influence mechanism of CeO2 on the oxidation resistance of composites. The results show that the CeO2 particles are distributed around the TaC particles in the Ni matrix, and the oxidation behavior of composites with different CeO2 content conforms to the linear kinetic law. The oxide film is mainly composed of NiTa2O6 and a small amount of NiO. The generation reactions of Ta2O5 and NiTa2O6 induce a high expansion and compressive stress in oxide scale, leading to the formation of nonprotective oxide film with pores and cracks on the surface. As the addition of CeO2 increases from 0 wt% to 2 wt%, the thickness of oxide scale on composites obviously reduces from 505 μm to 122 μm, and the Ni and Ta oxides content decreases, leading to the reduction of pores and cracks in oxide scale. The Ce ion generated from the dissolution of CeO2 particles mainly distributes in the Ta oxides during the oxidation process, which hinders the outward diffusion of Ni and Ta ions, resulted in the improved oxidation resistance of TaC/Ni composites.

Enhanced Thermodynamic Stability of Delithiated Nano-LiCoO2 by Lanthanum Doping.

The dynamic environment within lithium-ion batteries induces significant changes in local thermodynamic functions, hampering the accurate prediction of the stability of the cathodes during cycling. While delithiation primarily affects the surface properties of the cathode structure, there is a lack of fundamental understanding concerning the evolution of interfacial energies with varying stoichiometry. Here, we used microcalorimetry to quantify the thermodynamic changes between the stoichiometric and partially delithiated nano-LiCoO2 states for the first time. A mild delithiation from LiCoO2 to Li0.71CoO2 caused a surface energy reduction, negatively affecting the adhesion between adjacent grains by ∼0.4J/m2. The introduction of lanthanum at 1.0 atom % reduced the surface energy of the stoichiometric LiCoO2 while forcing a constant surface energy state during delithiation down to Li0.57CoO2. This reduced the thermodynamic stress between grains during lithium cycling, mitigating degradation mechanisms. The lanthanum-induced surface stabilization also inhibited the coarsening and dissolution of the cathode particles. We used electron microscopy to propose an atomistic mechanism by which the lanthanum doping pins surface dissolution for improved cathode stability.

Nanoformulated fenbendazole as an attractive approach for treating neurocysticercosis: in vitro and in vivo studies

Purpose This work aimed to develop fenbendazole nanocrystals to evaluate their effects on the energetic metabolism of Taenia crassiceps cysticerci, following an intracranial inoculation in mice. Methods Fenbendazole was nanoformulated by the antisolvent method using poloxamers 188 and 407 as stabilizers. The nanosuspensions were lyophilized without cryoprotectants and the nanocrystals were characterized in terms of particle size, zeta potential, and dissolution performance. The in vivo study was performed in infected animals treated with nanoformulated fenbendazole and raw drug and their metabolic impact was quantified by analyzing specific metabolites. Results Fenbendazole samples were obtained by nanoprecipitation in > 80% yield. The average particle size of the freeze-dried samples was between 372 nm and 1600 nm. The nanosystems released a greater amount of the drug into the solution, compared to the raw drug. The in vivo studies showed that the fenbendazole-treated groups induced gluconeogenesis, partial blockage of the TCA cycle, and increased protein catabolism. As seen, the nanoformulation presented a greater effect on these parameters than the raw drug leading to remarkable modifications in the metabolism of the parasite, which in turn can influence the overall course of the infection and treatment outcomes. Conclusion These findings suggest that nanoformulated fenbendazole may be considered a valuable approach for an effective treatment of neurocysticercosis.

Soft Ca2+-induced pea protein gels through mild heating: Controlling elasticity and fracturing behavior

With the rising demand for plant-based protein, understanding the formation of pea protein gels induced by calcium is important for manufacturing of food products with appealing textural properties. Moreover, the moderate temperature processing is becoming of greater and greater interest, based on conditions used for food fermentation. The objective of this study is to understand the structural and rheology behaviour of calcium-induced pea protein aggregates at moderate plateau temperatures i.e. in the range 30–45 °C with holding times from 0 to 60,000s. Based on the combination of confocal fluorescence microscopy (CLSM) imaging, rheology and IR spectroscopy, our results show that despite the relatively low temperature range, thermal agitation not only allows for partial protein particle dissolution, but also induces interactions leading to soft gel formation. Within a shorter holding time (0–600s) range, higher Gʹ/Gʹ0 (t) were observed at 40 °C and 45 °C, the end elastic modulus reaching for any parameters tested at least 1000 Pa. As the holding time was extended to 60,000s, the effect of temperature became less pronounced, i.e., all gels reached similar high values of Gʹ even for the low temperature of 30 °C, which is nearly 3–4 times higher than that formed at 600s holding time (at the temperature plateau). IR spectroscopy measurements showed that the protein secondary structure remained stable within the holding time ranging from 0s to 6,000s, while significant but moderate changes were monitored when extending the holding time to 60,000s, which correlated with a more progressive yielding observed in rheology, pointing to the formation of apparently more fragile physical gels. The combination of the techniques shows that the gel formation and strengthening mainly originated from rearrangements at the colloidal level leading to a denser network, while molecular rearrangements only intervened at the longest holding times (i.e, 60,000s).

Investigation of the sintering behavior of nanoparticulate SiC by molecular dynamics simulation

Sintering is a valuable processing technique utilized to create bulk materials from powder compacts. In recent years, sintering has a garnered significant attention in the research community due to its versatility and applicability in various fields, including additive manufacturing. Herein, we investigate the sintering kinetics and mechanism of SiC nanoparticulate using molecular dynamics simulations. The surface morphology, microstructure, radial distribution function, mean square displacement, atomic displacement distribution, structural transformation, and diffusion coefficient are analyzed in detail. The free surface surrounding the neck undergoes a reconstruction to eventually reach an equilibrium dihedral angle. The neck rapidly grows and aligns with the surface, causing the SiC particle to transform from an original spherical shape into a twists shape. The concentration of shear stress results in a change of the local lattice structure from the face-centered cubic phase to amorphous phase in the surface. With an increasing sintering time, the dominant diffusion mechanism gradually shifts from surface diffusion to interface diffusion. This trend leads to a rise in the atomic migration, the consumption of interface energy, and the degree of particle fusion. Ultimately, the sintered SiC particles have the spherical shape, low surface energy, and stable structure. Additionally, the high mobility of melted atom causes a gradual dissolution of SiC particle into the large particle from the surface towards the interior. This process leads to high-altitude concentration structures that facilitate atomic migration. These results shed light on an atomic sintering mechanism in SiC nanoparticulate for applications in the preparation of nanostructured materials, and additive manufacturing.

Effect of CO2 mixing on the rheological and electrochemical properties of fresh mortar at the early age

The study aimed to elucidate the mechanism behind rheological modification due to CO2 mixing at the mixing and post-mixing stages from an electrochemical perspective. The results indicated that CO2 mixing reduced the flowability while increasing penetration resistance and static yield stress. The electrostatic attraction between particles with opposite surface charges and the bridging effect of calcium carbonate constitute the primary factors for influencing the rheological properties of mortar at an early age. The altered surface charge of carbonized cement particles, primarily resulting from CO2 injection lowering the pH and ion concentration, reversed the zeta potential of particles from the traditionally negative charge (-3.59 mV) to a positive value (+13.3 mV). Furthermore, CO2 mixing further enhanced the dissolution of cement particles and accelerated the hydration process, thereby increasing the rate of structural build-up. CO2 mixing was demonstrated to be a potential rheological modifier for 3D-printed concrete applications.

Microstructural Characterization of Dry Powder Inhaler Formulations Using Orthogonal Analytical Techniques

PurposeFor locally-acting dry powder inhalers (DPIs), developing novel analytical tools that are able to evaluate the state of aggregation may provide a better understanding of the impact of material properties and processing parameters on the invivo performance. This study explored the utility of the Morphologically-Directed Raman Spectroscopy (MDRS) and dissolution as orthogonal techniques to assess microstructural equivalence of the aerosolized dose of DPIs collected with an aerosol collection device.MethodsCommercial DPIs containing different strengths of Fluticasone Propionate (FP) and Salmeterol Xinafoate (SX) as monotherapy and combination products were sourced from different regions. These inhalers were compared with aerodynamic particle size distribution (APSD), dissolution, and MDRS studies.ResultsAPSD testing alone might not be able to explain differences reported elsewhere in invivo studies of commercial FP/SX drug products with different Advair® strengths and/or batches. Dissolution studies demonstrated different dissolution rates between Seretide™ 100/50 and Advair® 100/50, whereas Flixotide™ 100 and Flovent® 100 had similar dissolution rates between each other. These differences in dissolution profiles were supported by MDRS results: the dissolution rate is increased if the fraction of FP associated with high soluble components is increased. Principle component analysis was used to identify the agglomerate classes that better discriminate different products.ConclusionsMDRS and dissolution studies of the aerosolized dose of DPIs were successfully used as orthogonal techniques. This study highlights the importance of further assessing invitro tools that are able to provide a bridge between material attributes or process parameters and invivo performance.

Morphometric characteristics and spatiotemporal heterogeneity of microplastics on the north-east coast of India

The study analysed microplastics (MPs) in surface waters along the north-east coast of India and focused on the spatiotemporal distribution and morphometric characteristics of 800 particles for environmental insights. The MPs were consistently present in all water masses, with an average abundance of 0.67 ± 0.66 particles/m3 during the monsoon and 0.12 ± 0.08 particles/m3 post-monsoon. Fragments and fibers were dominant in both seasons, comprising over 83% and 12%, respectively. In terms of colours, blue was significantly dominant during the post-monsoon (H, χ2 (5) = 15.38, p < 0.01); however, such variation was absent during the monsoon. Spatially, significant variance in abundance (F4, 34 = 8.542; p < 0.01) and across colours and forms during the monsoon was correlated with land-based inputs from the Hooghly River. FTIR analysis revealed ten polymer types, predominantly polyethylene (44%). SEM observations indicated that 80% of particles exhibited polymer ageing from oxidative weathering. The size distribution of MPs varied notably, with a higher proportion of < 0.3mm (16.7%) during the monsoon, possibly due to increased particle disintegration. The study noted MPs had low to moderate circularity, with increased irregularity during the monsoon due to heavy precipitation and river flushing. An initial risk assessment of MP pollution in surface waters on the north-east coast revealed a low-risk state. Acrylonitrile butadiene styrene (ABS) was identified as the most hazardous MP polymer. A wide range of toxic trace elements were found in MPs in these waters. The findings from the study deepen our knowledge of MPs and their fate in the pelagic zone, which supports the development of science-based policies that effectively reduce MP pollution.

The Particle Drifting Effect: A Combined Function of Colloidal and Drug Properties.

The particle drifting effect, where nanosized colloidal drug particles overcome the diffusional resistance of the aqueous boundary layer adjacent to the intestinal wall and increase drug absorption rates, is drawing increasing attention in pharmaceutical research. However, mechanistic understanding and accurate prediction of the particle drifting effect remain lacking. In this study, we systematically evaluated the extent of the particle drifting effect affected by drug and colloidal properties, including the size, number, and type of the moving species using biphasic diffusion experiments combined with computational fluid dynamics simulations and mass transport analyses. The results showed that the particle drifting effect is a sequential reaction of particle dissolution/dissociation in the diffusional boundary layer, followed by absorption of the free drug. Therefore, factors affecting the rate-limiting step, which can be either process or both under different circumstances, alter the particle drifting effect. Experimental results also agree with the theory that the particle dissolution rate is dependent on particle size, concentration, and drug solubility. In addition, rapid bile micelle dissociation and bile salt absorption facilitated drug absorption by the particle drifting effect. Our findings explain the highly dynamic nature of the particle drifting effect and will contribute to rational formulation development and better bioavailability prediction for formulations containing colloidal particles.

Influencing the powder particle transport in high-speed laser melt injection

Using high-speed laser melt injection (HSLMI), it is possible to generate wear-resistant metal matrix composite (MMC) surfaces on tools with great productivity. Since high laser intensities are required for reaching high process speeds, strong interactions can occur between powder particles and the laser beam. In order to reduce the interaction time and gain a better understanding of the role of particle transport in the HSLMI process, trajectories of spherical fused tungsten carbide (SFTC) particles were analyzed using high-speed imaging. The trajectories were divided into a path outside the laser beam and a path inside the laser beam. The identified interaction mechanisms were particle deformations, the formation of agglomerates, and particle disintegration. The volume flow rate of the feeding gas was found to have a decisive influence on the travel time of the particles, whereas the powder feed rate and the working distance of the powder nozzle only had a minor influence. Consequently, an increased volume flow rate led to a significant reduction of interactions between SFTC particles and the laser beam.

Mechanical behaviour of granular materials undergoing grain dissolution

Geotechnical engineering projects are often at risk from threats related to mineral dissolution and loss of particles that constitute the matrix of the geomaterial. Moreover, the impact of climate change can exacerbate these risks by accelerating the physical processes. To address such challenges, it is a pre-requisite to understand and quantify the effect of mineral dissolution on geomechanical behaviour. A general theoretical approach to mechanical consequences of geomaterials experiencing mineral dissolution was first proposed. Following, a series of oedometer tests were conducted using mixtures of salt and sand with various salt contents to observe and characterise the effect of dissolution on the mechanical behaviour of granular materials. The dissolution of salt crystals was performed in three different stress states to observe the stress-dependent response of the material. The effect of dissolution was dependent both on the amount of dissolved salt particles and the applied stress state. The laboratory experiments and the discussion followed shares insights into the effect of grain dissolution on the mechanical behaviour of granular materials and proved the potential of the framework presented in this paper. Finally, the paper ends by discussing the engineering implications bearing in mind the climate change we are facing today.

Laser powder bed fusion of NbTi low-temperature superconductors

This study investigates the superconducting properties of additive manufactured in-situ NbTi alloy using laser powder bed fusion. Laser parameters were optimised for a maximum microstructural density and lowest Nb segregation fraction. These characters have been achieved at the sample built with an energy density of 3.33 J/mm2, where it shows a density value of 6.12 g/cm3, undissolved Nb fraction of 0.05 %, and randomly distributed equiaxed grains with an average size of 10–20 μm. Post-processing of the as-fabricated (AF) sample was explored as a route to collapse residual porosity and dissolve residual segregated Nb particles using hot isostatic pressing (HIP) and heat treatment, respectively. HIPing resulted in a decrease of the undissolved Nb particle fraction to 0.035 %. Heat treatment at 1250 °C for 24 h, followed by aging at 400 °C for 2 h, was found to result in the complete dissolution of Nb particles and precipitation of the ɑ-Ti phase that works as pinning centres to increase the superconducting properties. The grain size increased in both post-processes to 400–500 μm. Electrical and magnetic properties were also measured for the AF, HIP and heat-treated samples. The thermal variation of electrical resistivity showed a critical temperature (Tc) range of 9.8–9.0 K, 9.6–9.1 K and 9.9–8.8 K for the AF, HIP, and heat-treated samples, respectively, which were close to the values obtained from magnetic measurements. The critical current density (Jc) was calculated using Bean’s model employing the magnetic hysteresis loops. The AF condition showed a negligible value of Jc (5 × 10−3 kA/mm2), which improved to 0.28 kA/mm2 and 2.65 kA/mm2 for the HIPed, heat treated conditions, respectively (at 4.2 K, 5 T). Mechanical tensile testing was performed for the heat-treated sample to ensure both mechanical and superconducting properties would achieve the required performance, where achieves ultimate tensile strength value of 930 MPa, with 8 % elongation.

Analysis of the Wear Parameters and Microstructure of High-Carbon Steel in Order to Identify Its Tribological Properties

Alloyed high-carbon steels are materials primarily intended for components operating under conditions of intense tribological wear. The carbides present in the microstructure of these materials significantly contribute to improving the wear resistance of such alloys. However, changes in the morphology of these precipitates can considerably alter the wear rate, leading to a deterioration in the properties of the materials. Therefore, this study aims to analyze the influence of several factors on the tribological wear of alloyed high-carbon steel. The research included friction tests under various load conditions and different sliding paths. Additionally, the samples were subjected to heat treatment to change the morphology of the observed precipitates. The tribological tests were conducted in a block-on-ring configuration under dry friction conditions. The tribological tests were analyzed statistically using analysis of variance (ANOVA). The results of the statistical analysis indicated that the primary factor influencing the observed differences between the samples was the heat treatment time of the material. Additionally, there were no significant statistical differences when pressure and friction path were varied. These findings, in conjunction with the SEM studies, allowed for the evaluation of the wear mechanism. The results demonstrated that, within the adopted tribological system, no alterations in the wear mechanism were observed with changes in test parameters. The observed differences in wear properties between the samples were found to be related to their heat treatment. The heat treatment resulted in alterations to the particle size distribution, with the annealing of the material at an elevated temperature leading to the dissolution of finer particles within the material. An increase in the average diameter of the carbide present in the material was observed to improve the wear resistance of the alloy tested.