Heat exchangers, nuclear power plants, and other engineering and manufacturing operations all involve high temperatures. These systems have a very big temperature gradient, which has a substantial impact on the fluid's transport characteristics. Under such circumstances, using the linear Boussinesq approximation and taking into account the constant thermophysical parameters for the ambient liquid become meaningless. Thus, under the impact on the angled magnetic field and joule heating, the radiative convection flow of the blood-based tetrahybrid nanoliquid in a squeezing channel is examined in this work. The base fluid that contains the distributed alumina, gold, silver, and titania nanoparticles is blood. Through suitable transformations, the partial governing equations were decreased into nonlinear ordinary differential equation's, which are then resolved mathematically applying the fourth-order accurate BVP4C technique. The increase in the viscous dissipation parameter corresponds toward the notable elevation on the blood temperature profile. The rate of heat transfer 57.4519% improved in Au-Ag-Al2O3-TiO2/blood than that of pure blood.