Capacity For Dissemination Research Articles

How effective crowdsourced data during crisis emergency? A case of the 2018 Palu-Donggala earthquake

In disaster situations, updated geographic data is crucial for disaster relief efforts. OpenStreetMap (OSM) has demonstrated significant value in disaster response scenarios due to its capacity for rapid data collection and dissemination, since the 2010 Haiti earthquake. This study investigates the quality of OSM data during the 2018 Palu-Donggala earthquake, focusing on how contributor expertise affects data reliability and how effectively OSM data supports decision-making in emergencies. The research highlights the critical role of OSM in providing timely geospatial information, with 205 contributors mapping roads and buildings in Palu City and Donggala Regency within just three days of the earthquake. Our findings show that while road data exhibited substantial topological errors—7,085 errors primarily due to overshoots—building data had considerably fewer errors, with only 76 recorded. This disparity suggests that OSM data for buildings was of higher quality during the crisis. The preference of eight out of nine mapper types for building data over road data further underscores the value of OSM in emergencies, as experienced mappers tended to focus on features that were less error-prone. The study also evaluates contributor behavior, revealing that while a significant portion of contributors were inactive, a majority of experienced contributors remained engaged. This finding indicates the potential for inactive expert mappers to return and contribute in future crises. Additionally, the study assesses the rapid collection of data by OSM and its impact on decision-making. The National Disaster Management Agency of Indonesia (BNPB) and the ASEAN Coordinating Centre for Humanitarian Assistance (AHA Centre) effectively utilized the data to provide updates on fatalities, injuries, and displacement, facilitating a swift and equitable distribution of aid.

Coccidiose aviária: impactos e características da doença

An excellent poultry production in the current national and international commercial scenario is directly related to an adequate sanitary control, since, in situations of incorrect management, adult chicks and chickens can be affected by several diseases, such as avian eimeriosis, caused by the obligate intracellular apicomplex protist Eimeria spp. which generates numerous losses to agribusiness. Among the main species that cause economic impact on poultry farming, the species E. acervulina, E. maxima, and E. tenella stand out, especially due to their high capacity for dissemination and the severity of the disease presentation. Sanitary measures to control coccidiosis, such as rigorous cleaning of sheds and bedding, as well as the responsible use of anticoccidial drugs, require extensive planning and commitment on the part of producers. The objective of this study was to carry out a literature review on avian coccidiosis in order to better understand the characteristics of the agent and to relate the pathogenesis to the methods of diagnosis, control and prevention of this disease, since the impact of the disease is masterful.

Donor country official development assistance in health R&D: domestic economic burden vs. medical disseminative capacity

Abstract This study examines domestic determinants of donor country official development assistance (ODA) in health research and development (R&D). It argues that health R&D ODA is negatively related to domestic economic burden, i.e. pressures that donor governments face because of economic issues in their own country, while also positively influenced by long-standing capabilities in medicine and medical research that are projected globally. Using panel data on forty-four donor countries over a 6-year period, the study finds support for a negative relationship between domestic economic burden and donor country health R&D ODA. It also finds a positive relationship between medical disseminative capacity (MDC) and donor country health R&D ODA, as well as with the ratio of health R&D ODA to overall ODA. While domestic economic burden dampens the overall appetite for health R&D ODA, MDC helps to reverse this and ensures that the proportion of ODA that goes to health R&D in developing countries is increased.

The international dissemination of China’s English academic journals on Twitter: Structure, theme and impact

Objective/Significance: To measure the international communication capacity of China’s English academic journal papers based on social media platforms. Method/Process: Social network analysis, content analysis and emotion analysis were used to describe the diffusion structure of China’s English academic journal papers on Twitter from the aspects of network structure and identify important node users, explore the identity characteristics and emotion characteristics of users as well as diffusion capability of journals of different disciplines. Conclusion/Discovery: Journal articles in the fields of natural sciences and engineering as well as humanities and social sciences exhibit a strong positive correlation between their diffusion structure and network size. Networks with a mixed diffusion structure typically have larger network sizes. The users occupying key positions in the diffusion network typically have profile information that is academically relevant. The retweets and comments are mainly statements without emotional inclination, and the comments are mainly summary descriptions of the papers. The distribution of diffusion width, diffusion strength and diffusion speed of each discipline is significantly different. There is a significant positive correlation between the diffusion structure of papers and their diffusion capabilities. Innovation/Value: To reveal the diffusion structure and characteristics of China’s English academic journal papers on social media platforms, so as to provide reference for expanding the visibility of China’s English academic journals and improving the international dissemination capacity of China’s English journals.

Livestock and poultry breeding farms as a fixed and underestimated source of antibiotic resistance genes.

The excessive use of antibiotics, disinfectants, and drugs in livestock and poultry breeding has resulted in a rise in the presence of antibiotic resistance genes (ARGs). Antibiotic-resistant bacteria (ARB) and ARGs have been widely found in animal feces, farm wastewater, and farm air. ARGs can not only spread across media through adsorption and migration, but also transfer resistance across bacterial genera through horizontal gene transfer. Livestock breeding has become a fixed and unavoidable source of ARGs in the environment. Existing technologies for controlling ARGs, such as composting, disinfection, and sewage treatment, are not efficient in removing ARB and ARGs from waste. Furthermore, the remaining ARGs still possess a strong capacity for dissemination. At present, antibiotics used in animal husbandry are difficult to replace in a short period of time. The growth and potential risks of resistance genes in livestock and poultry breeding sources in the receiving environment are not yet clear. In this paper, we summarize the current situation of ARGs in the livestock and poultry breeding environment. We also explain the key environmental processes, main influencing factors, and corresponding ecological risks associated with ARGs in this environment. The advantages and disadvantages of current technologies for the removal of ARGs are primarily discussed. There is a particular emphasis on clarifying the spatiotemporal evolution patterns and environmental process mechanisms of ARGs, as well as highlighting the importance and urgency of developing efficient pollution control technologies.

Organizational green culture and employees’ green behavior: a moderated mediation model with employees’ environmental awareness and organizational disseminative capacity

ABSTRACT Based on the social information processing theory, a conceptual model was proposed in which employees’ environmental awareness was considered a mediator and organizational knowledge disseminative capacity was considered a moderator to deeply analyze the effect of organizational green culture on employees’ green behavior. The method of multi-regression analysis and structural equation modeling were used to verify the hypotheses based on the results of the questionnaire of 321 employees. The results show that organizational green culture has a positive effect on employees’ green behavior; two dimensions of employees’ environmental awareness have a positive direct effect on employees’ green behavior; employees’ environmental awareness has a mediating effect on the relationship between organizational green culture and employees’ green behavior; and organizational knowledge disseminative capacity moderates the relationship between organizational green culture and employees’ environmental awareness.

Cadherin Expression Profiles Define Glioblastoma Differentiation and Patient Prognosis.

Cadherins are cell-cell adhesion proteins which have been strongly implicated in cancer invasion, dissemination and metastasis capacity; thus, they are key players in the epithelial-to-mesenchymal transition (EMT) program. However, their role in glioblastoma (GBM), a primary central nervous system aggressive tumor, remains to be clarified. N-, E- and P-cadherin expression was analyzed on a large series of GBMs, characterized with clinical, imaging and neuropathological parameters, as well as with patients' survival data. In addition, cadherins' expression was studied in match-recurrent cases. Using TCGA data, cadherin expression profiles were also evaluated according to GBM transcription subtypes. N-cadherin expression was observed in 81.5% of GBM, followed by E-cadherin in 31% and P-cadherin in 20.8%. Upon tumor recurrence, P-cadherin was the only significantly upregulated cadherin compared with the primary tumor, being positive in 65.8% of the cases. Actually, P-cadherin gain was observed in 51.4% of matched primary-recurrent cases. Cadherins' co-expression was also explored. Interestingly, E- and N-cadherin co-expression identified a GBM subgroup with frequent epithelial differentiation and a significant survival benefit. On the other hand, subgroups with P-cadherin expression carried the worse prognosis. P- and N-cadherin co-expression correlated with the presence of a mesenchymal phenotype. Expressions of isolated P-cadherin or E- and P-cadherin co-expression were associated with imaging characteristics of aggressiveness, to highly heterogeneous tumors, an d to worse patient survival. Classical cadherins co-expression subgroups present consistent clinical, imaging, neuropathological and survival differences, which probably reflect different states of an EMT-like program in GBM.

The neuroepidemiological and social risks in neonates related to the Zika virus

Introdução: Entre os anos de 2015 e 2016, o Brasil apresentou um aumento de casos de microcefalia em neonatos, durante uma epidemia de Zika Vírus (ZIKV) - um Flavivírus descoberto em 1947 na floresta de Zika, Uganda. Durante esse período foi confirmada a relação entre a contaminação por ZIKV na gestação e alterações cerebrais congênitas graves em recém-nascidos. As consequências de tal correlação foram profundas, afetando famílias e comunidades e exigindo uma mobilização significativa de recursos e apoio para os cuidados e desenvolvimento das crianças afetadas. Objetivo: O objetivo geral deste estudo é associar a infecção pelo ZIKV com os distúrbios congênitos neurológicos. Metodologia: Consiste em revisão analítica de literatura, realizada a partir de artigos científicos e base de dados de parâmetros seguros, tais quais SciELO, PubMed, Google Acadêmico e Ministério da Saúde. Além de uma visita técnica para um embasamento científico com uma profissional da área, bem como uma intervenção social, desenvolvida para orientação de gestantes, por meio de um folder informativo. Desenvolvimento: Dentre os riscos neurológicos, deletérios ao feto durante o desenvolvimento, a microcefalia mostrou-se o sinal mais evidenciado entre as crianças afetadas, relacionando-se à capacidade de disseminação transplacentária e ao mecanismo apoptótico das células embrionárias. Entre a população atingida, observou-se maior incidência na região Nordeste, entre mães solteiras, com idade maior que 30 anos, baixa escolaridade, autodeclaradas negras, de baixa renda e residentes em áreas com menor cobertura em políticas públicas. Ademais, entre os desfechos, o óbito entre os neonatos atingidos teve média de 1,4 meses, além de prematuridade e baixo peso ao nascer, relacionando condições nutricionais e de saúde com fatores sociais. Por mais, notabilizou-se que a obtenção de alterações em neonatos, por vezes, foi evidenciada somente após o nascimento e o diagnóstico fora dificultado no início epidêmico. Entretanto, o impacto no enfrentamento mostrou-se integral não somente para as crianças, mas às famílias atingidas, evidenciando a necessidade do amparo e a imperiosidade de ações educativas voltadas à proteção contra o vírus. Considerações finais: Pelo exposto, concluiu-se que os riscos neurológicos em neonatos decorrentes do ZIKV estiveram associados a uma tríade de aspectos: as condições sociodemográficas e ambientais facilitaram a disseminação rápida do vírus notadamente entre a população com maiores vulnerabilidades sociais, desencadeando danos neurológicos aos fetos em desenvolvimento, maiores no primeiro trimestre da gestação. A prevenção destaca-se como uma das formas mais importantes de ação em saúde no combate à proliferação desse vírus.

Physicochemical Characterization of Novel Bacteriophages of Pseudomonas syringe from Northwest Iran.

Bacterial canker, caused by Pseudomonas syringae, is a devastating disease of stone fruit trees worldwide. The bacterium has a broad host range and a high capacity for adaptation and dissemination, owing to its high mutation rate and horizontal gene transfer. Traditional control methods based on copper compounds and antibiotics have resulted in the development of resistance in the bacterial population. Thus, alternative approaches are needed, such as phage therapy. This study aimed to characterize the physicochemical and biological properties of novel Pseudomonas syringae pv. syringae (Pss)-specific phages isolated from the soils of northwestern Iran. Seventy-five phage isolates were obtained, and their host range was determined against various bacterial pathogens. Five phages exhibiting the highest lytic activity against Pss and a narrow host range were selected for subsequent analysis. The stability of the selected phages was assessed under different conditions such as ultraviolet irradiation, temperature, pH, NaCl concentration, and chloroform exposure. The selected phages demonstrated significant effectiveness invivo, exerting substantial suppression on the population of Pss. This reduction was observed for both individual phages and when the phages were utilized as a mixture. The findings indicate that phages have the potential to be used as biocontrol agents in agriculture.

Abstract 4134: The abscopal effect of combination IRE with αPD-1 treatment against PDACs

Abstract Pancreatic ductal adenocarcinoma (PDAC) is associated with a high capacity of metastatic dissemination, which results in a dismal 5-year relative survival rate. Irreversible electroporation (IRE) represents an innovative intervention utilizing short high-voltage electric pulses to induce cell death through either permanent membrane lysis or disruption of cellular homeostasis. Previous studies from our lab have demonstrated that the combination of IRE and immune checkpoint blockade using anti-PD-1 antibody (αPD-1) enhances the infiltration of CD8+ cytotoxic T cells, significantly prolonging survival in an orthotopic murine PDAC model. However, the impact of IRE/αPD-1 on metastatic PDAC tumors, known as the abscopal effect, remains unclear. In this investigation, we bilaterally implanted C57BL/6J mice with subcutaneous KRAS* PDAC tumors, treating the right flank tumors with or without IRE, in conjunction with or without αPD-1 administered intraperitoneally. Tumor growth in both the treated (with or without IRE) and untreated (abscopal) left flank tumors was closely monitored until humane euthanasia or long-term survival. In a separate study, mice serum and tumor tissues were collection on the 5th day post-IRE/αPD-1 treatment. Luminex cytokine assays were conducted on the collected serum, and immunostaining was performed on tumor tissue. Results demonstrated significantly enhanced antitumor activity in both IRE-treated and untreated tumors on mice treated with combined IRE and αPD-1, leading to a marked extension of overall survival. Luminex cytokine assays revealed a substantial increase in crucial cytokines, including IL-2, IFN-gamma, IL-18, IL-19, and IL-3, known for their pivotal roles in fostering cytotoxic T lymphocyte development, promoting T cell differentiation into effector T cells, and facilitating the recruitment of effector CD8+ T cells to the tumor microenvironment. Moreover, immunofluorescence staining of tumor tissue illustrated a notable accumulation of CD169+ macrophages in IRE-treated tumors compared to untreated tumors. Tumors from the combined IRE with αPD-1 group exhibited increased CD8+ T cell accumulation compared to other groups. These data suggest IRE combined with PD-1 blockade promotes robust antitumor immune, leading to systemic antitumor activity and robust abscopal effect. Citation Format: Qizhen Cao, Nicholas A. Egan, Weiyi Peng, Chun Li. The abscopal effect of combination IRE with αPD-1 treatment against PDACs [abstract]. In: Proceedings of the American Association for Cancer Research Annual Meeting 2024; Part 1 (Regular Abstracts); 2024 Apr 5-10; San Diego, CA. Philadelphia (PA): AACR; Cancer Res 2024;84(6_Suppl):Abstract nr 4134.

Enhanced attenuation of chikungunya vaccines expressing antiviral cytokines

Alphaviruses are vector-borne, medically relevant, positive-stranded RNA viruses that cause disease in animals and humans worldwide. Of this group, chikungunya virus (CHIKV) is the most significant human pathogen, responsible for generating millions of infections leading to severe febrile illness and debilitating chronic joint pain. Currently, there are limited treatments to protect against alphavirus disease; thus, there is a tremendous need to generate safe and effective vaccines. Live-attenuated vaccines (LAVs) are cost-effective and potent immunization strategies capable of generating long-term protection in a single dose. However, LAVs often produce systemic viral replication, which can lead to unwanted post-vaccination side effects and pose a risk of reversion to a pathogenic phenotype and transmission to mosquitoes. Here, we utilized a chimeric infectious clone of CHIKV engineered with the domain C of the E2 gene of Semliki Forest virus (SFV) to express IFNγ and IL-21—two potent antiviral and immunomodulatory cytokines—in order to improve the LAV’s attenuation while maintaining immunogenicity. The IFNγ- and IL-21-expressing vaccine candidates were stable during passage and significantly attenuated post-vaccination, as mice experienced reduced footpad swelling with minimal systemic replication and dissemination capacity compared to the parental vaccine. Additionally, these candidates provided complete protection to mice challenged with WT CHIKV. Our dual attenuation strategy represents an innovative way to generate safe and effective alphavirus vaccines that could be applied to other viruses.

Silibinin is a suppressor of the metastasis-promoting transcription factor ID3

BackgroundID3 (inhibitor of DNA binding/differentiation-3) is a transcription factor that enables metastasis by promoting stem cell-like properties in endothelial and tumor cells. The milk thistle flavonolignan silibinin is a phytochemical with anti-metastatic potential through largely unknown mechanisms. Hypothesis/purposeWe have mechanistically investigated the ability of silibinin to inhibit the aberrant activation of ID3 in brain endothelium and non-small cell lung cancer (NSCLC) models. MethodsBioinformatic analyses were performed to investigate the co-expression correlation between ID3 and bone morphogenic protein (BMP) ligands/BMP receptors (BMPRs) genes in NSCLC patient datasets. ID3 expression was assessed by immunoblotting and qRT-PCR. Luciferase reporter assays were used to evaluate the gene sequences targeted by silibinin to regulate ID3 transcription. In silico computational modeling and LanthaScreen TR-FRET kinase assays were used to characterize and validate the BMPR inhibitory activity of silibinin. Tumor tissues from NSCLC xenograft models treated with oral silibinin were used to evaluate the in vivo anti-ID3 effects of silibinin. ResultsAnalysis of lung cancer patient datasets revealed a top-ranked positive association of ID3 with the BMP9 endothelial receptor ACVRL1/ALK1 and the BMP ligand BMP6. Silibinin treatment blocked the BMP9-induced activation of the ALK1-phospho-SMAD1/5-ID3 axis in brain endothelial cells. Constitutive, acquired, and adaptive expression of ID3 in NSCLC cells were all significantly downregulated in response to silibinin. Silibinin blocked ID3 transcription via BMP-responsive elements in ID3 gene enhancers. Silibinin inhibited the kinase activities of BMPRs in the micromolar range, with the lower IC50 values occurring against ACVRL1/ALK1 and BMPR2. In an in vivo NSCLC xenograft model, tumoral overexpression of ID3 was completely suppressed by systematically achievable oral doses of silibinin. ConclusionsID3 is a largely undruggable metastasis-promoting transcription factor. Silibinin is a novel suppressor of ID3 that may be explored as a novel therapeutic approach to interfere with the metastatic dissemination capacity of NSCLC.

Energy planning tools applied into urban photovoltaic: the importance of compatibilizing with the constructions

The necessity for an efficient way to develop energy planning in urban environments is increasingly part of the reality of cities. In this sense, tools with the ability to evaluate the installation of distributed generation systems become widely necessary for the elaboration of efficient projects. In this sense, our article aims to evaluate 20 tools from the point of view of urban photovoltaic (PV) planning, considering functionalities such as simulation, scenario generation, bottom-up, availability and application in urban PV; PV is the most widespread power plant in urban environments, with great dissemination capacity.

Forecasting the population development of within-season insect crop pests in sub-Saharan Africa: the Pest Risk Information Service

Abstract Smallholder farmers are the mainstay of the agricultural economies of sub-Saharan Africa (SSA), where they produce several crops, predominantly centered on maize. Smallholder productivity remains limited resulting from a range of confounding factors, but a primary cause is loss from pests and diseases, particularly insects. To improve productivity, recommendations for the mitigation of crop loss globally include early-warning and management systems for in-season indigenous pests. There are many early-warning systems in temperate regions; however, such systems are poorly established in Africa. This is in part due to the need for a combination of pest modeling, data handling and dissemination infrastructure, capacity, and resource provision. While each of these components is progressing in Africa, the means to successfully deploy such systems remain limited. To bridge this, the development of the Pest Risk Information Service (PRISE) began in 2017 for farmers in SSA. Implemented in Kenya, Ghana, Malawi, and Zambia, PRISE developed temperature-driven phenology models for major maize, bean, and tomato pests. Using downscaled and processed Earth Observation data to drive the models, PRISE partnered with African national agencies to communicate pre- and in-season pest alerts that forecast the time to act against key insect pests. Alerts were designed to be integrated into country-specific Good Agricultural Practice (GAP) recommendations to provide a complementary package to agricultural stakeholders. End line studies with farmers showed that those who received information about the target crops including PRISE pest forecasts, generally reported better outcomes in terms of reduced losses and increased incomes compared with farmers who did not.

Genomic analysis of penicillin-binding proteins and recombination events in an emerging amoxicillin- and meropenem-resistant PMEN3 (Spain9V-3, ST156) variant in Taiwan and comparison with global descendants of this lineage.

From 2008 to 2020, the Taiwan National Notifiable Disease Surveillance System database demonstrated that the incidence of non-vaccine serotype 23A invasive pneumococcal disease (IPD) approximately doubled. In this study, 276 non-repetitive pneumococcal clinical isolates were collected from two medical centers in Taiwan between 2019 and 2021. Of these 267 pneumococci, 60 were serotype 23A. Among them, 50 (83%) of serotype 23A isolates belonged to the sequence type (ST) 166 variant of the Spain9V-3 clone. Pneumococcal 23A-ST166 isolates were collected to assess their evolutionary relationships using whole-genome sequencing. All 23A-ST166 isolates were resistant to amoxicillin and meropenem, and 96% harbored a novel combination of penicillin-binding proteins (PBPs) (1a:2b:2x):15:11:299, the newly identified PBP2x-299 in Taiwan. Transformation of the pbp1a, pbp2b, and pbp2x alleles into the β-lactam-susceptible R6 strain revealed that PBP2x-299 and PBP2b-11 increased the MIC of ceftriaxone and meropenem by 16-fold, respectively. Prediction analysis of recombination sites in PMEN3 descendants (23A-ST166 in Taiwan, 35B-ST156 in the United States, and 11A-ST838/ST6521 in Europe) showed that adaptive evolution involved repeated, selectively favored convergent recombination in the capsular polysaccharide synthesis region, PBPs, murM, and folP genome sites. In the late 13-valent pneumococcal conjugate vaccine era, PMEN3 continuously displayed an evolutionary capacity for global dissemination and persistence, increasing IPD incidence, leading to an offset in the decrease of pneumococcal conjugate vaccine serotype-related diseases, and contributing to high antibiotic resistance.A clonal shift with a highly β-lactam-resistant non-vaccine serotype 23A, from ST338 to ST166, increased in Taiwan. ST166 is a single-locus variant of the Spain9V-3 clone, which is also called the PMEN3 lineage. All 23A-ST166 isolates, in this study, were resistant to amoxicillin and meropenem, and 96% harbored a novel combination of penicillin-binding proteins (PBPs) (1a:2b:2x):15:11:299. PBP2x-299 and PBP2b-11 contributed to the increasing MIC of ceftriaxone and meropenem, respectively. Prediction analysis of recombination sites in PMEN3 descendants showed that adaptive evolution involved repeated, selectively favored convergent recombination in the capsular polysaccharide synthesis region, PBPs, murM, and folP genome sites. In the late 13-valent pneumococcal conjugate vaccine era, PMEN3 continuously displays the evolutionary capacity for dissemination, leading to an offset in the decrease of pneumococcal conjugate vaccine serotype-related diseases and contributing to high antibiotic resistance.

Unfolding and Developing Disseminative Capacity

Unfolding and Developing Disseminative Capacity

Whole-Genome Sequencing of 11 High-Risk Clone ST111 Pseudomonas aeruginosa Isolates from French Hospitals.

This study reports high-quality genomes of 11 sequence type 111 (ST111) isolates of Pseudomonas aeruginosa. This ST is known for its worldwide dissemination and high capacity to acquire antibiotic resistance mechanisms. This study used long- and short-read sequencing to provide high-quality closed genomes for most of the isolates.

The Birth of the Black Death: Biology, Climate, Environment, and the Beginnings of the Second Plague Pandemic in Early Fourteenth-Century Central Asia

The article considers the environmental context of the early fourteenth-century Tian Shan region, in which the Second Plague Pandemic in general and the Black Death in particular commenced. It suggests that this major evolutionary event may have started in the context of profound eco-biological and climatic shifts, triggering bacterial activity (i.e., Yersia pestis infection, transmission, and dissemination capacity) and initiating what became the single harshest human killer in known history. In particular, the article underscores how landscape change, weather conditions, and seismic activity in that region prepared the ground for the beginning and early spread of the plague pandemic.

Fake news detection: a systematic literature review of machine learning algorithms and datasets

Fake news (i.e., false news created to have a high capacity for dissemination and malicious intentions) is a problem of great interest to society today since it has achieved unprecedented political, economic, and social impacts. Taking advantage of modern digital communication and information technologies, they are widely propagated through social media, being their use intentional and challenging to identify. In order to mitigate the damage caused by fake news, researchers have been seeking the development of automated mechanisms to detect them, such as algorithms based on machine learning as well as the datasets employed in this development. This research aims to analyze the machine learning algorithms and datasets used in training to identify fake news published in the literature. It is exploratory research with a qualitative approach, which uses a research protocol to identify studies with the intention of analyzing them. As a result, we have the algorithms Stacking Method, Bidirectional Recurrent Neural Network (BiRNN), and Convolutional Neural Network (CNN), with 99.9%, 99.8%, and 99.8% accuracy, respectively. Although this accuracy is expressive, most of the research employed datasets in controlled environments (e.g., Kaggle) or without information updated in real-time (from social networks). Still, only a few studies have been applied in social network environments, where the most significant dissemination of disinformation occurs nowadays. Kaggle was the platform identified with the most frequently used datasets, being succeeded by Weibo, FNC-1, COVID-19 Fake News, and Twitter. For future research, studies should be carried out in addition to news about politics, the area that was the primary motivator for the growth of research from 2017, and the use of hybrid methods for identifying fake news.

Knowledge transfer based on disseminative capacity, absorptive capacity, and learning: a comparative study between Brazil and Germany

PurposeThis study aims to assess suppliers’ learning from knowledge transfers with a global truck manufacturer, considering both source and supplier capacity, and the cultural proximity between the parties.Design/methodology/approachA case study was conducted between two factories, one in Brazil and one in Germany. This study adopted a mixed-method sequential explanatory approach, which involves a quantitative phase followed by a qualitative one to provide a better understanding of the studied phenomenon. Quantitative data were collected from the automaker’s suppliers in both countries and analyzed using factor and inferential analyses. Qualitative data were obtained from the automaker’s purchasing executives, and from the company’s suppliers in both countries. Content analysis was used to analyze data.FindingsResults suggest that both the source’s disseminative capacity and suppliers’ absorptive capacity had a positive effect on suppliers’ learning during knowledge transfers. The study also found out that cultural proximity among parties positively moderates the relationship between suppliers’ absorptive capacity and their learning. However, cultural proximity does not moderate the relationship between a source’s disseminative capacity and supplier learning.Practical implicationsThis study’s findings are important to foster knowledge transfers by developing absorptive and disseminative capabilities in the automakers industry, in which the implementation of interorganizational learning is quite challenging due to the large number of strategic providers.Originality/valueThis study contributes to theoretical and conceptual consolidation of knowledge transfer, which includes cultural proximity among parties and the source’s and supplier’s disseminative and absorptive capacities, respectively. This study constructs and validates a model of knowledge transfer using a large automaker with a worldwide presence.