Abstract. To analyze the impact of the COVID-19 pandemic on the prevention and control strategies for HIV and sexually transmitted infections (STIs) in Southern China. It seeks to understand how the pandemic affected the management of these infections and make a better preparation for the next COVID-19-like situation. This literature review was conducted by analyzing data from 4 databases, focused on epidemiological characteristics before and after 2020, changes in health policies, resource redistribution, and the implementation of prevention measures during the pandemic. The results indicate that COVID-19 prevention was prioritized, leading to challenges in the management of HIV and STIs due to resource redistribution and pressures on the healthcare system. Despite these difficulties, some innovative approaches used in the COVID-19 prevention emerged to address the gaps, including the use of e-medicine and targeted community outreach which helps to compensate for the negative impacts on HIV/STI control. This review highlights the necessity of developing new strategies with innovative technologies that can balance the control of multiple infectious diseases during global health crises, ensuring that critical health services remain effective even in times of widespread disruption.
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