Disposable Lenses Research Articles

Risk Factors for Bacterial Keratitis and Severe Disease in Hydrogel Contact Lens Users: A Multicenter Case-Control Study and Case-Only Analysis.

To assess risk factors for contact lens (CL)-related bacterial keratitis, cases and high-risk controls were enrolled. Using high-risk controls can help elucidate whether certain CL types or modalities are attributable to disease burden if risky wear patterns are similar between the cases and controls. This analysis identified whether such CL factors were associated with the occurrence of bacterial keratitis. In addition, a case-only analysis determined CL factors associated with severe disease. From 2018 to 2021, 158 controls were enrolled at University Hospitals of Cleveland Eye Institute, and 153 bacterial keratitis cases were enrolled across 14 sites in the United States. Cases were soft CL wearers with either culture-proven bacterial keratitis or a corneal infiltrate with an overlying epithelial defect within the central 4 mm of the cornea, uveitis, or significant pain. Fungal, protozoan, or nonsoft CL wear-related microbial keratitis cases were excluded. Controls were recruited from high-risk CL wearers with no history of disease. All participants completed a questionnaire related to demographics, type of CL used, wearing schedule, lens handling practices, and storage case handling. Cases with ulcer/infiltrate size ≥2 mm in size, presence of hypopyon, or had fortified antibiotics prescribed were classified as severe keratitis. Univariate and multivariable logistic regression was used to assess association of CL variables with the occurrence of bacterial keratitis as well as occurrence of severe disease among the cases only. Compared with the control cohort, cases were older (mean age 45.6 vs. 38.9 years), had more males (42.5% vs. 23.6%), and had more current or former smokers (41.7% vs. 12.9%). There were no significant associations between CL material (silicone hydrogel vs. not) or CL type (daily disposable vs. reusable) and occurrence of bacterial keratitis. More than two-thirds (67.3%) of cases were classified as severe. Among cases only, univariate analyses found current smokers to have increased risk of severe disease (OR=2.87; 95% CI 1.13-7.26, P=0.03). Adjusting for age, sex, and smoking among the cases only, daily disposable lenses were protective against severe disease (OR=0.32; 95% CI 0.11-0.89, P=0.03). Reusable lenses increased risk of severe microbial keratitis between 3.0- and 4.4-fold compared with compliant daily disposability. Compared with a high-risk control cohort, no specific lens factors were associated with occurrence of CL-associated bacterial keratitis. Among cases only, current smokers and patients wearing reusable lenses are at increased risk of severe keratitis. Daily disposable lenses were protective even when noncompliance to daily disposability was considered.

International trends in daily disposable contact lens prescribing (2000–2023): An update

PurposeDaily disposable contact lenses offer numerous benefits in terms of ocular health and wearer convenience. The purpose of this work is to update earlier surveys by describing global trends in daily disposable lens fitting between 2000 and 2023. MethodAn annual contact lens prescribing survey was sent to eye care practitioners in up to 71 countries between 2000 and 2023, inclusive. Data relating to 265,106 daily wear soft lens fits undertaken in 20 countries returning reliable longitudinal data were analysed in respect of daily disposable lens fitting. ResultsOverall, daily disposable lens prescribing increased over time, from 17.1 % of daily wear soft lens fits in 2000 to 46.7 % in 2023 (p < 0.0001). There were significant differences between countries in daily disposable lens prescribing (p < 0.0001), and between the percentage of males fitted with daily disposable lenses, as a proportion of all daily wear soft lenses (37.2 %), compared to females (35.2 %) (p < 0.0001). Daily disposable lens wearers are slightly younger at fitting than reusable soft lens wearers (31.0 vs 31.2 years, respectively) (p < 0.0001), although this difference is not clinically meaningful. Analysis of 50,240 daily wear soft lenses fitted recently (2019–2023) were found to be prescribed for the following replacement frequencies: daily – 47 %; monthly – 42 %; 1–2 weekly – 9 %; and ≥3 monthly – 2 %. ConclusionThere has been a substantial increase in daily disposable lens fitting throughout the first 24 years of this century. The gradual nature of this increase is commensurate with the staged introduction of daily disposable lens designs and expanded parameter ranges over the survey period.

Daily disposable soft lens sagittal depth and other lens parameter changes measured at room temperature (20 °C) and on-eye temperature (34 °C)

PurposeTo investigate the differences in contact lens sagittal depth (CL-SAG), base curve (BC), and overall lens diameter (OAD) of daily disposable (DD) SCLs at room temperature (20 °C) and on-eye (34 °C) temperature. MethodsTwelve different spherical daily SCLs were analyzed (labeled power −3.00 D) at 20 °C and 34 °C. The posterior CL-SAG, BC, and OAD were measured directly using a spectral domain OCT-based instrument (Optimec is830). ResultsThe CL-SAG range for the daily disposable lenses measured at 20 °C was 3468–4016 µm. At 34 °C, the DD CL-SAG of all lenses individually decreased compared to 20 °C (t = 7.78, p < 0.001), ranging from 3385 to 3913 µm. On average at the higher temperature, the measured overall lens diameter was smaller (t = 8.18, p < 0.001) and the BC was marginally steeper (t = 2.11, p = 0.058). ConclusionsSoft lens parameters change when equilibrated from room temperature (20 °C) to on-eye temperature (34 °C). All lenses shrink when going to on-eye temperature (both lens diameter and CL-SAG decreases), compared to lenses measured at room temperature by ISO standards. Higher water content materials tend to have greater changes to the lens parameters compared to lower water content material lenses.

Multifocal contact lens success predictability

PurposeThe current multi-study analysis combined data from three studies to quantify the relationship between the initial reaction to soft multifocal contact lens (MFCL) design types at dispensing and evaluate the predictability of overall vision satisfaction (OVS) and intention to purchase (ITP) after 1 week of wear. MethodThree prospective studies tested MFCLs over 1-week of wear following the same protocol, using a range of potentially predictive ratings at dispensing, and both OVS and ITP at 1-week as an indicator acceptance level. In each study, two of MyDay® multifocal, clariti® 1 day multifocal, Biofinity® multifocal (worn as a daily disposable lens) or 1 DAY ACUVUE® MOIST MULTIFOCAL were dispensed for 1-week of daily wear. OVS was recorded on a 100-point VAS and ITP on a 5-point LIKERT scale. Fourteen possible predictors were entered in the statistical model, and predictability was assessed using Chi-square Automatic Interaction Detector (CHAID) statistical test. ResultsA total of 210 participants (152 female & 58 male; 53.9 ± 6.5 years, range 41–71 years), representing 420 MFCL fits, equally distributed between emergent n = 65, established n = 70 and advanced n = 75 presbyopes, completed the studies. OVS on dispensing was the predictor of both OVS (p < 0.001) and ITP (p < 0.001) at 1-week. For OVS predictability, 70.8 % with OVS at dispensing > 91 points reported good OVS at 1-week and 73.4 % with OVS on dispensing ≤ 80 points reported poor OVS at 1-week. For ITP predictability, 74.6 % with OVS at dispensing > 94 points reported a positive ITP at 1-week and 65.9 % with OVS on dispensing ≤ 63 points reported negative ITP at 1-week. ConclusionOverall vision satisfaction at the time of dispensing MFCLs is a powerful indicator of both OVS and ITP after 1-week of wear. Initial patient subjective assessments provide a clinically useful indicator of the likeliness of success.

Single-Use Lens Compromise During Selective Laser Trabeculoplasty.

Damage to disposable selective laser trabeculoplasty (SLT) lenses correlated with the amount of total laser energy. Furthermore, greater lens damage was associated with diminished patient treatment response. Disposable SLT lenses have been observed to be damaged during use by laser, potentially affecting therapeutic response. This study sought to identify factors associated with the magnitude of lens damage and its effect on treatment outcomes. We analyzed 113 eyes from 82 patients who underwent SLT between 2020 and 2021 at an American academic medical center. For each procedure, we recorded baseline patient characteristics, procedure settings, physician age (as a possible factor causing laser defocus due to accommodation), and area of lens damage. Treatment response was calculated as the difference between preoperative and postoperative intraocular pressure (IOP). Area of lens damage was associated with greater total laser energy ( r =0.34, P <0.001) and greater mean energy per application ( r =0.37, P <0.001). IOP reduction decreased with increasing lens damage ( r =-0.19, P =0.022). Lens damage was not associated with patient characteristics indicative of glaucoma severity or user settings (physician age and slit lamp used). Greater IOP reduction was associated with higher preop IOP ( r =0.46, P <0.001) and a smaller cup-to-disc ratio ( r =0.22, P =0.036). IOP reduction was not associated with retinal nerve fiber layer thickness, patient age, or the number of glaucoma medications. Increased laser damage to disposable SLT lenses was associated with diminished treatment effect. The amount of damage was correlated with total and average laser energy, but not patient or physician factors. Overall, these findings call for reconsideration of using disposable SLT lenses as part of routine practice.

Wear Experience with a daily disposable soft contact lens for astigmatism in current wearers of a reusable soft toric contact lens.

The purpose of this study was to evaluate the wear experience of satisfied wearers of a particular reusable toric soft contact lens when refit into a water surface technology daily disposable toric soft contact lens. 30 participants completed the study over three visits. At the first visit, subjects were refit into with their habitual reusable toric soft contact lens (comfilcon A) to maximize fit and vision. Subjects returned after one week and were then refit into the study daily disposable soft contact lenses (verofilcon A) and completed surveys of their initial impressions of comfort, vision, and satisfaction. Participants wore the study lenses for two weeks, and then returned for their final visit to complete a vision and ocular health check. At the final visit, subjects also completed surveys to rate their overall and end-of-day comfort, quality of vision, stability of vision, and dryness using a visual analog scale (VAS). Participants also answered questions about their wear experience with the lenses. Overall median and interquartile range (IQR) of all data and surveys was calculated. Initial impressions of the study lenses revealed a median (IQR) score of 85 (28) for vision, 91 (25) for comfort, and 87 (21) for satisfaction. Overall VAS scores after two weeks of wear found median scores of 93 (16) for quality of vision, 88 (28) for stability of vision, and 91 (20) for comfort. End-of-day median scores were 82(27) for quality of vision, 90 (35) for stability of vision, and 80 (38) for comfort. Overall dryness scores were 20(45) and end-of-day dryness was 39 (46). Median(IQR) binocular logMAR visual acuity with the study lenses was -0.16(0.1). Median rotation of the lenses was 0(4.3) degrees. Participants wearing the daily disposable study lenses for astigmatism gave high scores in vision and comfort both at initial fitting and after two weeks of lens wear. Results showed that satisfied wearers of comfilcon A reusable toric soft contact lenses can be successfully refit with verofilcon A daily disposable contact lenses.

EVALUATION OF WEAR EXPERIENCE WITH WATER SURFACE DAILY DISPOSABLE LENSES IN SATISFIED REUSABLE SOFT CONTACT LENS WEARERS.

Soft contact lens wearers are often prescribed the same lens material and modality for multiple years if patients express satisfaction and no significant problems with lens fit or ocular health are noted upon evaluation. Despite their satisfaction, it is possible that other lenses exist that could provide additional health or convenience benefits and still provide satisfied lens wear experience. In this study, wearers of a specific monthly replacement lens brand (comfilcon A) were recruited for an open-label study. The habitual contact lens prescription was optimized for 2 weeks of wear and participants confirmed that they were satisfied with their habitual lenses before being refit with daily disposable lenses (verofilcon A). Participants responded to visual analog scale (VAS) survey about their initial impressions of the lenses. After 2 weeks of lens wear, participants completed a final study visit and completed surveys about lens wear experiences with the daily disposable study lenses. Fifteen male and 15 female participants completed the study. Median (IQR) binocular LogMAR visual acuity was -0.20(0.12), which is equivalent to 10/12.5 Snellen acuity. Initial impression surveys revealed median (interquartile range) of 92.5(22.3) for quality of vision; 95.0(19.3) for comfort; and 91.5(19.3) for satisfaction. At the final visit, median scores for EOD quality of vision was 86.5(24.0); EOD comfort was 84.5(30.3), and EOD dryness 25.5(47.0). Median overall VAS scores were 92.5(16.0) for vision; 88.0(18.3) for comfort, and 17.5(25.8) for dryness. Median satisfaction with the study lenses was scored 9(2.8) on a 1-10 scale. In this study, satisfied wearers of comfilcon A reusable lens were refit with Verofilcon A daily disposable lenses and showed high satisfaction scores with the new lenses, showing that refitting these patients can allow patients to have lenses with more frequent replacement and maintain satisfaction with daily lens wear.

Change in objective bulbar redness and symptoms after refit of weekly and monthly lenses into a water-gradient daily disposable lens material

Purpose. The purpose of this pilot study is to identify if fine graduated differences in objective redness of the eye exist in a cohort of non-symptomatic contact lens wearers. The pri- mary objective is the evaluation of change in bulbar redness when a non-symptomatic, 2-4 week contact lens wearer, is refitted to a Delefilcon A lens material. Secondary objectives include the determination of limbal redness, corneal and bulbar staining, and wearing comfort. Material and Methods. 52 habitual, asymptomatic, full time soft contact lens wearers were enrolled in a multicenter study. At the baseline visit, bulbar and limbal redness were measured objectively using the Redness-Scan of the Keratograph 5M (K5M). Habitual lenses, lens care type, comfort ratings and staining data were captured at baseline visit. A wash out phase of 6 ± 1 days was conducted in which the subjects did not wear any lenses before Delefilcon A lenses were dispensed at visit 2 (V2) for a wearing period of 26 ± 5 days. A follow up visit was planned after 6 ± 1 days from V2 and a final visit after additional 20 ± 4 days. During visits 2, 3 and 4, the same objective measurements were carried out and corresponding subjective data was captured. ANOVA, t-test for paired sam- ples, homogeneity test and Wilcoxon signed rank test were used for the statistical analyses. Results. A total number of 49 complete data sets were suc- cessfully evaluated. Objectively measured bulbar redness decreased by 0.121 (p = 0.003) from the baseline compared to the final visit. In the same period, limbal redness reduced by 0.151 (p = 0.000). In addition, an increase from 36 at baseline to 47 at V4 grade 0 ratings regarding corneal staining, and from 32 to 39 regarding bulbar staining was found, respec- tively. The averaged comfort rating with habitual lenses was 79.7 ± 16.6 compared to the final visit 89.0 ± 10.8. Conclusion. In the context of classic subjective grading hab- its which use fully grades in 1.0 steps, the objective Red- ness-Scan was able to detect finely graduated differences in the cohort of non-symptomatic wearers. The daily disposable test product delivers benefits to wearers in the form of re- duced bulbar and limbal redness, reduced corneal and bulbar staining, and statistically and clinically increased contact lens wearing comfort. Keywords contact lens, bulbar redness, wearing comfort

Contact Lens Wearer’s Outlook Towards Recommended Replacement Schedule of Contact Lens in Mumbai

Background: Non-compliance is one of the major reasons of CL related complications. Various research studies have been done over the past three decades to find reasons for patient non-compliances. Use of CLs over the recommended replacement schedule has been one of the major reasons leading to CLs complications. It is evident that the CLs user are often unaware of their non-compliance towards lens care and maintenance regimen. Even after introduction of daily disposable lenses and one-step multipurpose solution non-compliance towards CLs use is still a major problem in CLs patients. The complications due to patient noncompliance can be sometimes irreversible. This research will help us understand CL user reasons of intentionally or unintentionally being non-compliant to recommended replacement frequency.&#x0D; Method: All CL users willing to share their experience participated in this questionnaire based online survey which was designed with the help of focused group discussion.&#x0D; Results: Most of the CL wearer prefer buying pairs for at least 6 months at a time. Almost 80% of CL wearers do not replace their CL as per MRRF. 70% of those who participated wore CL for more than 10 hours per day. The male and female ratio is almost equal in the participants participated in the research.&#x0D; Conclusion: Research done in the past suggest incomplete knowledge imparted to the wearer or CL forgetting the instructions given to them at dispensing. Research also suggest some CL wearer knowingly are non-compliant to MRRF. This study tries to find loopholes in a CL practice by finding reasons of non-compliance as per CL wearers prospective and probable suggestion from the user itself. An ECP is a paramedical person who has the right to prescribe them, whether according to MRRF or as per their knowledge of the patient’s ocular status. For e.g., an antibiotic medicine is supposed to be prescribed for 3 days or 5 days, once or twice is decided by the medical practitioner prescribing. As this research shows over 50% of the CL wearer said that their 'ECP said its okay'.

Defining Daily Disposable Contact Lens Wear in a Clinical Study.

The U.S. Food and Drug Administration regulates contact lenses as prescription medical devices and defines daily disposable lenses for single use; however, safety comparisons between daily disposable and reusable lenses rely on the lens-wearing regimen. When inappropriately discerned, studies may erroneously report replacement regimen, resulting in inaccurate risk rates. This study aimed to explore different measures for defining daily disposable wearers in the context of a clinical study. A secondary analysis of data from five multisite fieldings (n = 1059) from the Contact Lens Risk Survey was performed. Descriptive statistics were used to examine self-reported lens replacement, use of lens case, and manufacturer's recommended replacement frequency as defined by the participants' selection of their habitual lenses using a photographic aide. Daily disposable wearers were identified as reporting daily replacement (by self-report and lens identification) and not using a lens case. If there was a discrepancy among these three factors, the lens assignment was assessed as a majority response (two of three) or as missing if conflicting information was reported. The cohort was approximately two-thirds (68.7%) female and ranged from 12 to 33 years of age. A total of 154 participants (14.5%) were classified as daily disposable wearers and 896 (84.6%) as reusable wearers. Congruence was observed among all three daily disposable assignment factors for only 106 wearers (68.8%). The greatest discrepancy among daily disposable wearers was the report of using a lens case (n = 32 [20.8%]). In contrast, reusable lens wearers were more likely to report agreement across all three factors (n = 798 [89.1%], P < .001). This analysis suggests that the report of not using a lens case is a more conservative surrogate for true single-use lens wear, as one in five may be storing and reusing their daily disposable lenses.

Knowledge and Compliance among Contact Lens Wearers Living in Kuala Lumpur, Malaysia: A Cross-Sectional Study.

Many factors determine the success of wearing contact lens, including knowledge and compliance towards lens care. This study aimed to evaluate the level of knowledge and compliance between two groups of adult contact lens wearers in Kuala Lumpur, Malaysia. A total of 60 participants aged 18-30 years old volunteered to participate in this study (30 participants prescribed contact lenses at the Universiti Kebangsaan Malaysia [UKM] optometry clinic and 30 participants fitted at private practices). Participants were interviewed using a structured questionnaire consisting of nine questions on basic knowledge related to lens wear and 13 questions on compliance, categorised into questions on the cleaning process, disinfection, accessories care and replacement schedule. All participants wore disposable contact lens 53.3% (n = 32) participants preferred using monthly disposable lenses. Both groups had the same level of knowledge, except knowledge of the effects of makeup (P < 0.000) and duration of the solution used for cleaning (P < 0.010), showing lack of knowledge on contact lenses among participants in private practices group. There were no significant differences between the groups in terms of the level of compliance with the cleaning process (P = 0.830), disinfection (P = 0.725), accessories care (P = 0.865) and replacement schedule (P = 0.699). Participants from UKM optometry clinic had better knowledge on wearing contact lens; moreover, both groups had good compliance towards lens care. Contact lens practitioners should provide all the necessary information to contact lens wearers so that they are equipped to handle contact lenses correctly, which would minimise the risk of eye complications.

Affluence and Contact Lens Prescribing.

To assess the impact of national affluence on the extent of prescribing of various types of soft contact lenses. Using information derived from a large bank of contact lens prescribing data, the relationship between the percentage prescribing of daily disposable, toric, silicone hydrogel, and multifocal contact lenses versus the gross domestic product at purchasing parity per capita (GDP [PPP]) was determined for all countries in which contact lens prescribers returned survey forms relating to greater than 100 contact lens fits between 2017 and 2021, inclusive. Data from 39 countries were analyzed, comprising 94,181 contact lens fits. The relationship between percentage contact lens prescribing versus GDP (PPP) was highly statistically significant for daily disposable lenses (r 2 =0.35, P <0.0001), marginally significant for toric lenses (r 2 =0.08, P =0.06), and not significant for silicone hydrogel lenses (r 2 =0.01, P =0.42) or multifocal lenses (r 2 =0.02, P =0.35). The rate of prescribing daily disposable contact lenses, and to a lesser extent toric lenses, is related to national affluence. The contact lens industry, practitioners, and governments/regulatory bodies should remain cognizant of this association and, where possible, reduce cost barriers to the purchase of such contact lens products so that they can be prescribed based on important clinical, refraction, and lifestyle considerations.

Laser-Enabled Surface Treatment of Disposable Endoscope Lens with Superior Antifouling and Optical Properties.

Endoscopes are ubiquitous in minimally invasive or keyhole surgeries globally. However, frequent removal of endoscopes from the patient’s body due to the lens contaminations results in undesirable consequences. Therefore, a cost-effective process chain to fabricate thermoplastic-based endoscope lenses with superior antifouling and optical properties is proposed in this research. Such multifunctional surface response was achieved by lubricant impregnation of nanostructures. Two types of topographies were produced by femtosecond laser processing of metallic molds, especially to produce single-tier laser-induced periodic surface structures (LIPSS) and two-tier multiscale structures (MS). Then, these two LIPSS and MS masters were used to replicate them onto two thermoplastic substrates, namely polycarbonate and cyclic olefin copolymer, by using hot embossing. Finally, the LIPSS and MS surfaces of the replicas were infiltrated by silicone oils to prepare lubricant-impregnated surfaces (LIS). Droplet sliding tests revealed that the durability of the as-prepared LIS improved with the increase of the lubricant viscosity. Moreover, the single-tier LIPSS replicas exhibited longer-lasting lubricant conservation properties than the MS ones. Also, LIPSS-LIS replicas demonstrated an excellent optical transparency, better than the MS-LIS ones, and almost match the performance of the reference polished ones. Furthermore, the LIPSS-LIS treatment led to superior antifouling characteristics, i.e., regarding fogging, blood adhesion, protein adsorption, and microalgae attachment, and thus demonstrated its high suitability for treating endoscopic lenses. Finally, a proof-of-concept LIPSS-LIS treatment of endoscope lenses was conducted that confirmed their superior multifunctional response.

Laser Induced Damage to Disposable Gonioscopy Lenses During Selective Laser Trabeculoplasty.

The substitution of reusable gonioscopy lenses for disposable gonioscopy lenses during selective laser trabeculoplasty (SLT) has occurred over the last few years to mitigate infection risk. However, concerns have been raised regarding the potential of laser damage to the lens itself during SLT, which can lead to laser scattering, increasing the possibility of unintended adverse effects. We have noticed that over 90% of the disposable lenses used for SLT sustained some sort of laser-induced damage with routine laser energies (0.4-1.0 mJ). Comparisons of clinical efficacy of SLT, measured by reductions in intraocular pressure (IOP), between the use of reusable and disposable lenses has shown no difference in IOP reduction, with both groups achieving a 20% reduction in IOP over the course of 12 months. While no clinical difference in outcomes was observed, further investigation into this issue, most notably the possibility of adverse effects due to laser scattering, is warranted.

Wear Experience of a Water Surface Daily Disposable Contact Lens in Existing Silicone Hydrogel Planned Replacement Lens Wearers.

PurposeThe health benefits of silicone hydrogel lens materials and a daily replacement modality have been demonstrated in previous studies; however, existing planned replacement lens wearers may resist changing to a new lens replacement schedule. The purpose of this study is to evaluate the wear experience of satisfied planned replacement silicone hydrogel wearers when refit into a silicone hydrogel daily disposable lens.Patients and MethodsIn this open-label, non-comparison study, satisfied wearers of two week planned replacement contact lenses were evaluated for inclusion criteria and refit with optimized prescriptions in their habitual lenses. At a follow-up visit one week later, participants were refit with the study daily disposable lenses and completed visual analog scale (VAS) surveys of initial quality of vision, comfort, and satisfaction. Participants returned for a final visit after two weeks of wearing the study daily disposable lenses. At the final visit, VAS surveys for both overall and end of day (EOD) vision, comfort, and dryness were completed. Overall median and interquartile range (IQR) were assessed for all surveys in the study.ResultsThirty individuals completed the study (29.1 ± 7.8 years old; 19 female). Median (IQR) results for the initial impression VAS surveys were 92.50(11.75) for quality of vision, 92.50(18.00) for comfort, and 93.00(18.00) for satisfaction. Final VAS survey results revealed median scores of 87.50(25.00) for EOD quality of vision and 82.50(51.25) for EOD comfort. The median overall quality of vision was 91.00(17.00) and overall comfort was 93.00(28.50). Median (IQR) overall dryness was 28.50(49.00) and median EOD dryness was 30.50(64.25).ConclusionThe findings of this study suggest that providers can successfully refit satisfied wearers of early generation silicone hydrogel planned replacement lenses into a new generation silicone hydrogel daily disposable lens while maintaining satisfaction.

Global contact lens prescribing 2000-2020

ABSTRACT Clinical relevance Contact lens prescribing data serve as a benchmark for eye care clinicians in assessing their own prescribing patterns and provide useful contextual information for researchers and the contact lens industry. Purpose To document global trends in contact lens prescribing during the first two decades of this century. Methods A longitudinal survey of contact lens prescribing was conducted by asking contact lens practitioners to provide 11 items of information from 10 consecutive contact lens fits between January and March each year from 1996 to 2020, inclusive. Results Data relating to 406,859 contact lens fits were collected from 71 countries between 1996 and 2020, generating 4.5 million data points. Demographic analysis for 61 nations returning ≥100 fits demonstrated that a majority of lenses (65–70%) were fitted to females. The average age of lens wearers was 30.8 ± 13.9 years for males and 32.5 ± 14.3 years for females. Trend analysis of 20 countries returning prescribing data for ≥13 years between 2000 and 2020 revealed the following: increase in the age of lens wearers; dramatic rise in the extent of fitting silicone hydrogel and daily disposable lenses; increased fitting of soft toric and multifocal lenses; increasing proportion of rigid lens fits in specialist (non-spherical) designs; incomplete provision of near contact lens corrections for contact lens wearing presbyopes; ongoing low levels of extended wear fits; and almost exclusive use of multi-purpose care systems. Daily disposable lenses were used for both full-time and part-time wear, whereas rigid and soft reusable lenses were primarily worn full time. Conclusions The evolution of international contact lens fitting over the first two decades of this century is documented. The data presented here may assist all stakeholders in advancing contact lens clinical practice, informing contact lens research, and guiding contact lens manufacturers.

Comfort and vision correlations in daily disposable multifocal lenses

Purpose: To evaluate the subjective responses to two daily disposable multifocal contact lenses (MFCLs), stenfilcon A (stenA-MF) and delefilcon A (delA-MF), and to see if there is a correlation between preferences based on vision and comfort.

Comfort and vision with two daily disposable multifocal lenses when worn by habitual multifocal contact lens wearers

Purpose: To evaluate subjective comfort and vision with two daily disposable multifocal contact lenses (MFCLs) in habitual MFCL wearers.

Assessment of a novel silicone hydrogel daily disposable lens among physically active subjects

Purpose: Physical exercise can change the body’s hydration status and blink rate that results in hyperosmotic tears. Increased osmolarity is related to contact lens (CL) dryness. Maintaining ocular surface homeostasis while wearing CLs is complex and has led to innovations in lens material and design. This study evaluated wear experiences of subjects that actively take part in regular sport or physical activity (PA) and subjects that don’t (NPA) while wearing a novel kalifilcon A (KA) daily disposable silicone hydrogel lens (DDSH) containing moisturizers and osmoprotectants.

Fitting success with stenfilcon A daily disposable multifocal lenses

Purpose: Multifocal contact lens (MFCL) fitting sometimes raises concerns about the number of fitting attempts required to determine the optimal lens prescription. This study compared the fit process and success rates of stenfilcon A (stenA) MFCL with delefilcon A (delA) MFCL when fitted to existing MFCL wearers in a randomized order.