Abstract In this paper, the impact of polarization mode dispersion (PMD) on system performance in coherent optical transmission assisted by optical phase conjugation (OPC) technique is numerically investigated for a 9-channel PM-4QAM system at 128Gbit/s. The OPC-aided transmission, amplified with lumped erbium doped fiber amplifier (EDFA), is a variation of the conventional dispersion-managed link, which is also called dispersion-inverted link. We demonstrate that introducing more OPCs along the link can partly suppress the PMD-induced impairments and thus improve the system performance significantly. Results of 960-km dispersion-managed transmission show that PMD effect will cause a performance penalty of 1.8 dB when using mid-link OPC (i.e., only 1-OPC), while this penalty will decrease to about 0.4 dB when employing 6-OPCs along the link. Comparing with conventional digital back-propagation (DBP) technique, a performance improvement of about 3.1 dB is observed with multi-OPCs when fiber PMD is equal to 0.1ps/ k m $\sqrt{km}$ .