A hydro–solar hybrid system is an important solution for expanding renewable generation capacity under the percepts of the energy transition. This type of association allows for the coordinated dispatch of solar and hydropower plants, resulting in operational benefits in terms of energy generation and reservoir management, that is, the better use of available water and energy resources. As in this case, the operation of the hydropower plant is associated with the cascade in which it operates, when it is hybridized (for example, by associating with a solar power plant), in addition to local changes, there are impacts on the operating conditions of the other hydropower plants in the same cascade. From such a perspective, this study presents an energy system management model for hybrid power plants composed of hydro and solar sources, aiming to optimize the joint operation and measure the operational consequences at the local level and in the cascade. The results from a case study of a hydro–solar power plant hybridization in the Tietê River (Brazil) revealed increased energy production and improvement in the operating conditions of the cascade’s reservoirs, while the grid capacity was found to be an important constraint that limits the capture of synergies resulting from the generation sources complementarity and thus on the benefits to the cascade.