To validate the ten-word test for immediate memory from the Alzheimer's Disease Assessment Scale-Cognitive section (ADAS-Cog) in detecting subjective cognitive decline (SCD) and mild cognitive impairment (MCI). 79 people aged 38∼80 years old participated in the study and they were classified as SCD (n = 55) or MCI (n = 24). The the Mann-Whitney U test showed that the ten-word test score was significantly different in SCD compared to MCI (p = 0.001, Figure 1). In particular, a cut-off score of 4.15 points had an 63% sensitivity and 87% specificity for discriminating MCI from SCD (AUC = 0.73, p = 0.001), while a cut-off score of 4.15 also had a sensitivity of 79% and a specificity of 83% for discriminating MCI from SCD in age > 60 years old adults (AUC = 0.82, p = 0.001), and a cut-off score of 4.35 points had a sensitivity of 90% and a specificity of 95% for discriminating MCI from SCD in those age > 60 years old adults with education level > 9 years (AUC = 0.93, p < 0.001) (Figure 2-3). Convergent validity was found between the ten-word test and ADAS-cog total scores (r = 0.56, p < 0.001), and the Mini-Mental State Examination (MMSE) (r = -0.28, p = 0.013) and the Montreal Cognitive Assessment-Basic (MOCA-B) (r = -0.20, p = 0.078). The ten-word test for immediate memory from the ADAS-Cog is a good to fair screening tool with adequate discriminant validity for administration in people with SCD and MCI.