Disappearance Of Wrinkles Research Articles

Effectiveness of Facial Acupressure and Acupuncture on Musculus Facei

Background: Fatigue on the face can affect the brightness of the face, if the facial muscles function well, the health of the face will be immediately visible. There are many facial care methods currently offered, which can be done with facial acupuncture and acupuncture. This study aims to determine the effectiveness of facial acupressure and acupuncture on the facial muscles, which has never been done before. Methods: Analytical experimental research was divided into two groups, the first group was given facial acupuncture treatment and the second group was given facial acupuncture treatment. The data obtained in the form of facial muscle relaxation is indicated by the disappearance of wrinkles on the face with a score of (1, 2, 3). The dependent variables are facial acupuncture and facial acupuncture. Inclusion criteria were women aged 40 – 50 years, agreed to take part in this study, and had no facial abnormalities. The exclusion criteria are women aged less than 40 years or over 50 years, and there are defects in the facial area. This research will be carried out in May – June 2023 at the Wijaya Surabaya doctor's practice and polyclinic. Results: The results of the study found that 20 minutes of facial acupuncture was useful for relaxing the facial muscles by up to 60%, on the sixth day the face looked brighter and cleaner, while acupuncture therapy on the facial muscles experienced relaxation of up to 60% on the sixth day with 30 minutes. The effectiveness of facial acupressure therapy is 10 minutes faster than acupuncture. Conclusion: Facial acupressure therapy and acupuncture therapy have proven to be effective in relaxing the facial muscles.

A comparative analysis of water immersion induced hand wrinkling in dermatological diseases

Skin wrinkling is hypothesized as an adaptive phenomenon that is generated as an evolutionary process. Water immersion-induced wrinkling is a non-invasive test graded from 0-5 that involves placing one’s hands into lukewarm water for a set amount of time. Despite the increased interest in skin rejuvenation, a baseline study describing the variation in water immersion induced hand wrinkling is still missing. We aim to experimentally compare the water immersion-induced wrinkling time in various dermatological conditions in the current study.One hundred patients from the Department of dermatology were evaluated based on their presenting Dermatoses like Psoriasis Vulgaris, Acral Vitiligo, and Hand Dermatitis were asked to place their hands in 25±1°C tap water to elicit water-induced wrinkling. Twenty-five patients were included as age-matched controls without any significant dermatoses. Following this, the time of early and complete disappearance of wrinkles was documented.: Out of 100 patients, water-induced wrinkling time was seen earliest in Dermatitis > healthy controls > Psoriasis>Vitiligo. rnThe formation of wrinkles diminished significantly as age advanced. Within the normal population, females participants took longer to develop water immersion-induced wrinkles compared to males.: There is a significant variation in the water immersion induced hand wrinkling pattern in patients with Dermatoses like Psoriasis, Vitiligo, and Hand Dermatitis due to structural alterations in the epidermis and dermis. Estrogen and the sympathetic nervous system play a significant role in water immersion-induced wrinkling. The role of estrogen in this phenomenon was a novel observation.

In-situ TEM investigation of MoS2 wrinkles and its effects on electrical properties

MoS2 has potential application in the fields of electronics and optics. However, thin films with non-uniform or local compressive strain can form winkles. The presence of wrinkles has great effects on the performance of the transition metal dichalcogenides (TMDs) materials. In this work, by in-situ transmission electron microscopy (TEM), we tracked the formation and disappearance of MoS2 wrinkles to reveal the microstructure of wrinkles and its effects on electrical properties. It is found that compressive stress can lead to the formation of wrinkles, and the wrinkles disappeared with removal of the stress. The εxx maps show that MoS2 nanosheets corrugated as the strain reached 3.3% for 15 layers, accompanied by new diffraction points in fast Fourier transform (FFT) image. In contrast, removal of the stress resulted in the disappearance of wrinkles and new diffraction points, and MoS2 nanosheets restored to its initial morphology. Moreover, wrinkles also affect the electrical properties of MoS2 nanosheets. The existence of wrinkles caused an increase of the current, and the disappearance of the wrinkles accompanied by the current decreased, which is due to the piezoresistive effect. This study is helpful to understand the properties of MoS2 nanostructures and is of great significance to the structural design in the electronic field.

ANM analysis of a wrinkled elastic thin membrane

In this work, we have investigated numerically the disappearance of wrinkles from a tended membrane by the Asymptotic Numerical Method (ANM) using the finite-element DKT18. The ANM is a path-following technique that has been used to solve bifurcation problems. We show numerically the influence of the terms corresponding to the membrane displacement gradient in the Föppl–von Kármán (FvK) theory on the bifurcation curves in the case of a stretched elastic membrane. We will also study numerically, by using the ANM algorithm, the influence of the thickness and of the aspect ratio on the re-stabilization of a rectangular elastic membrane during stretching. The results obtained by our model are compared with those obtained using the industrial code ABAQUS.

On the wrinkling and restabilization of highly stretched sheets

Wrinkles are commonly observed in uniaxially stretched rectangular sheets with clamped-clamped boundaries, and can disappear upon excess stretching. Here we explore this wrinkling and restabilization behavior both analytically and numerically. We find that Poisson’s ratio plays a crucial role in the wrinkling and restabilization behavior. Smaller Poisson’s ratio makes later onset of wrinkling, lower amplitude and earlier disappearance of wrinkles. In particular, when Poisson’s ratio is below a threshold, no wrinkles occur, which can be explained by the decreasing transverse compressive stresses with respect to the reducing Poisson’s ratio. Furthermore, based on the Koiter stability theory, we have semi-analytically predicted isola-center bifurcation points, through looking into the sign change of the quadratic terms of potential energy. Both theoretical buckling and restabilization points are in agreement with finite element results. Lastly, a 3D phase diagram on stability boundaries is provided and we find that when the aspect ratio is beyond a threshold, wrinkles may not occur in the center but are split into two packets near the stretching ends.

A modeling and resolution framework for wrinkling in hyperelastic sheets at finite membrane strain

Wrinkles commonly occur in uniaxially stretched rectangular hyperelastic membranes with clamped-clamped boundaries, and can vanish upon excess stretching. Here we develop a modeling and resolution framework to solve this complex instability problem with highly geometric and material nonlinearities. We extend the nonlinear Föppl-von Kármán thin plate model to finite membrane strain regime for various compressible and incompressible hyperelastic materials. Under plane stress condition, 2D hyperelastic constitutive models can be systematically deduced based on general 3D strain energy potentials, e.g., Saint-Venant Kirchhoff, neo-Hookean, Mooney-Rivlin, Gent model and Gent-Gent model. Moreover, we establish a novel and efficient numerical resolution framework combining a path-following continuation technique by Asymptotic Numerical Method (ANM) and a discretization by a spectral method. The main advantages of this framework include the generality for both compressible and incompressible materials, ease of programming, high precision and efficient continuation predictor. Based on the proposed approach, effect of different incompressible constitutive models on the post-buckling response is investigated, which shows that restabilization points and wrinkling amplitudes are quantitatively influenced. However, for compressible materials, Poisson’s ratio plays a critical role in the wrinkling and restabilization behavior. We find that smaller Poisson’s ratio makes later onset of wrinkling, lower amplitude and earlier disappearance of wrinkles. Besides, severe strain-stiffening phenomena are explored by accounting for phenomenological models such as Gent model and Gent-Gent model. Efficiency and accuracy of the proposed modeling and resolution framework were examined by comparing with some benchmarks.

Diffusion-induced wrinkling instability in a circular poroelastic plate

A poroelastic material can imbibe solvent and swell. When the material swells inhomogeneously or swells under external constraints, stresses can develop inside the material. The stresses can trigger mechanical instabilities in the material or even break the material, which have been often observed in experiments. In this paper, we study the wrinkling instability of a circular poroelastic plate, in the process of solvent molecules migrating into the plate from the edge. The critical conditions for the initiation and disappearance of wrinkles in the plate are presented.

Mercury-arc photolysis: A method for examing second messenger regulation of endothelial cell monolayer integrity

Cell-cell apposition in bovine pulmonary endothelial cell monolayers was modulated by inducing transient increases in intracellular adenosine 3′:5′-cyclic monophosphate (cAMP) and 1,4,5-inositol triphosphate (IP 3). This was accomplished by mercury-arc flash photolysis of o-nitrobenzyl derivatives of the second messengers (caged compounds). Second messenger release by the mercury-arc lamp was determined by radioimmunoassay of cAMP to have a t 1 2 of approximately 8 min. Each second messenger induced the phosphorylation of a distinct subset of cytoskeletal proteins; however, both IP 3 and cAMP increased vimentin phosphorylation. Actin isoform patterns were not altered by the second messengers. Intracellular pulses of IP 3 in pulmonary endothelial cells caused disruption of endothelial monolayer integrity as determined by phase-contrast microscopy and by visualization of actin stress fibers with rhodamine-phalloidin. Intracellular pulses of cAMP increased cell-cell contact, cell surface area, and apposition. IP 3 appeared to have its greatest effect on the actin peripheral band. In silicone rubber contractility assays this agent caused contraction of pulmonary microvascular endothelial cells as visualized by an increase in wrinkles beneath the cells. On the other hand, cAMP appeared to effect both the peripheral band and centralized actin domains. Caged cAMP caused relaxation of endothelial cells as visualized by a disappearance of wrinkles beneath the cells.

Contraction and relaxation of cultured mesangial cells on a silicone rubber surface

Glomerular mesangial cells (MC) in culture are believed to contract or relax in response to agents such as angiotensin II and cyclic AMP. However, cells grown on glass or plastic surfaces are limited in their response to vasoactive agents because of the rigid surfaces to which they adhere; thus, interpretation of a change in shape as contraction, relaxation, or detachment is difficult. We have grown MC on a flexible silicone rubber (dimethylpolysiloxane) substrate (DMPS), and studied with sequential photographs several models of cell contraction, relaxation, and detachment. When the cells contracted, the DMPS became wrinkled; when the cells relaxed, the DMPS lost wrinkles. In contrast, if the cells detached, the sheet lost wrinkles as the cells became smaller and rounder. Angiotensin II (5 X 10(-7) M), and calcium ionophore A23187 (2 X 10(-6) M) increased wrinkles in more than 30% of cells at 22 degrees C and more than 40% of the cells at 36 degrees C. The earliest effect was visible within five to 10 minutes at 22 degrees C and within one minute at 36 degrees C and increased until 40 minutes; thereafter, the cells relaxed and wrinkles were reduced. 10(-1) M Na azide prevented the increase in wrinkles produced by angiotensin II. Seventy-two percent of the angiotensin II-treated cells whose margins could be seen in their entirety, and 78% of the calcium ionophore-treated cells showed a reduction in surface area at a time when new wrinkles were appearing or wrinkles were increasing in size. Dibutyryl cyclic AMP, a known smooth muscle relaxant, produced a decrease or loss of wrinkles in 90% of the cells, and an accompanying increase in surface area. Untreated control cells, observed in conjunction with the above series, showed little change in wrinkles. Ten percent DMSO, an actin-translocating agent, produced a reversible disappearance of wrinkles. These models of contraction and relaxation could be distinguished from cell detachment; EDTA, for example, in the presence of zero calcium, diminished both cell size and wrinkles, with an accompanying lifting of cells from the surface. Similar results were obtained with cytochalasin B and chlorpromazine. Thus, the silicone rubber system accurately reflects the contraction, relaxation and detachment of cultured mesangial cells in response to a variety of agents.