Preoperative selection of perforator is one of the key steps for successful surgery. The purpose of this study is to simulate the selection process of the perforator of the flap using the 3D models of the deep inferior epigastric artery (DIEA). A retrospective study was performed of women who underwent deep inferior epigastric perforator flap breast reconstruction from January 2011 to July 2021. Construct 3D models of the DIEA using computerized tomography angiography images, and then computational fluid dynamics simulations were performed. Correlation and regression analyses were used to analyze the geometric and hemodynamic parameters. Statistical analysis suggested that the outlet flow was positively correlated with the inlet area (r=0.338, p=0.000), outlet area (r=0.840, p=0.000), the average radius of the perforator (r=0.592, p=0.000), and negatively correlated with the length of perforator(r=-0.210, p=0.024). The results of linear regression analysis showed that the outlet area (p=0.000), the average radius (p=0.000), and the length (p=0.044) of the perforator were the influencing factors on outlet flow. In multiple perforators analysis, there was a significant difference in the total outlet flow among single perforator, double perforators, and triple perforators (p=0.002). The successful implementation of this experiment provides a new approach for the selection of dominant perforators in the future.
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