This article deals with the existence and asymptotic stability in the p-th moment of a mild solution for Hilfer fractional stochastic delay differential equations in Hilbert spaces. Our main results are obtained by fractional calculus, semigroup theory, stochastic analysis, and the Banach fixed point theorem. Further, a new set of sufficient conditions for existence and asymptotic stability in the p-th moment is derived with the help of a fixed point technique. Additionally, we provide an example to demonstrate the reliability of our results.