Different Types Of Complications Research Articles

Predictive Modeling of Medical and Orthopaedic-Related 90-Day Readmissions Following Primary Total Hip Arthroplasty

The rate of unplanned hospital readmissions following total hip arthroplasty (THA) varies from 3 to 10%, representing a major economic burden. However, it is unknown if specific factors are associated with different types of complications (i.e., medical or orthopaedic-related) that lead to readmissions. Therefore, this study aimed to: (1) determine the overall, medical-related, and orthopaedic-related 90-day readmission rate; and (2) develop a predictive model for risk factors affecting overall, medical-related, and orthopaedic-related 90-day readmissions following THA. A prospective cohort of primary unilateral THAs performed at a large tertiary academic center in the United States from 2016 to 2020 was included (n = 8,893 patients) using a validated institutional data collection system. Orthopaedic-related readmissions were specific complications affecting the prosthesis, joint, and surgical wound. Medical readmissions were due to any other cause requiring medical management. Multivariable logistic regression models were used to investigate associations between pre-specified risk factors and 90-day readmissions, as well as medical/orthopaedic-related readmissions independently. Overall, the rate of 90-day readmissions was 5.6%. Medical readmissions (4.2%) were found to be more prevalent than orthopaedic-related readmissions (1.4%). The area under curve (AUC) for the 90-day readmission model was 0.71 (95% CI [confidence interval]: 0.69 to 0.74). Factors significantly associated with medical-related readmissions were advanced age, black race, education, Charlson comorbidity index (CCI), surgical approach, opioid overdose risk (NARX) score, and nonhome discharge. In contrast, risk factors linked to orthopaedic-related readmissions encompassed body mass index (BMI), PROM phenotype, non-osteoarthritis indication, NARX, and non-home discharge. Of the overall 90-day readmissions following primary THA, 75% were due to medical-related complications. Our successful predictive model for complication-specific 90-day readmissions highlights how different risk factors may disproportionately influence medical versus orthopaedic-related readmissions, suggesting that patient-specific, tailored preventive measures could reduce postoperative readmissions in the current value-based healthcare setting.

Evaluación mediante TC de las complicaciones de la úlcera gastroduodenal

Gastric and duodenal ulcers (GDUs) are decreasing both in frequency and rate of mortality. However, GDUs with complications continue to have higher mortality rates and are seldom suspected in patients presenting with acute abdomen. Although upper endoscopy plays a central role in the diagnosis and treatment of GDUs, CT is crucial when serious complications appear, namely uncontrolled acute haemorrhage, perforation, organ penetration, or gastric obstruction. Radiologists have a special role to play in these situations, providing the diagnosis and extent of complications, thus contributing to decision making which can range from conservative management to endoscopic, surgical or interventional radiology procedures. The aim of our study is to describe the CT indications and protocols for patients with a suspected GDU with complications and present the main imaging findings for the different types of complications, while providing differential diagnoses.

Ileostomy: Early and Late Complications

Abstract Introduction Ileostomy formation is performed for multiple purposes related to intestinal pathology, such as obstructive malignant or benign tumors, inflammatory bowel diseases, intestinal ischemia, and, for the most part, as a protective stoma in high-risk anastomosis. The creation of this surgical opening, despite being considered a simple procedure, is undoubtedly followed by complications in certain cases. Materials and Methods We conducted an electronic literature search in the MEDLINE database using the PubMed search engine. A total of 43 articles were included in the present review. Results/Discussion Over the course of the present work, we were able to explore different types of complications that can arise in patients with an ileostomy. High-output stomas were found to be associated with dehydration and electrolyte imbalance. Skin-related morbidity was shown to be present in a great percentage of patients. More severe complications, such as peristomal pyoderma gangrenosum and necrosis, are less frequent and require urgent management. Several risk factors were identified in cases of retraction, obstruction, prolapse, and parastomal herniation. Conclusion Even though ileostomies may present numerous benefits in certain patients, they are also associated with many complications, which should be avoided and quickly managed, because they can severely affect the quality of life of the patients. Surveillance and follow-up by a multidisciplinary team is strongly advisable, bearing in mind that a good performance on the part of the responsible surgeon is also a key factor.

Basal thumb arthritis surgery: complications and its management.

The management of complications after surgery for basal thumb arthritis is sometimes challenging, and there are no clear recommendations on how to evaluate and manage patients with residual symptoms. The aim of the present article was to review the most common complications after surgery for basal thumb arthritis, with an emphasis on resection arthroplasty, joint replacement and joint fusion. In addition, possible management strategies for the different types of complications will be highlighted.

Postoperative Complications After Neoadjuvant Chemotherapy Versus Upfront Surgery in Gastric Adenocarcinoma: A Population-Based Nationwide Study in Finland

BackgroundTo date, no large population-based studies have compared complications and short-term outcomes between neoadjuvant chemotherapy and upfront surgery in gastric cancer. More nationwide studies with standardized reporting on complications are needed to enable international comparison between studies. This study aimed to compare postoperative complications between neoadjuvant therapy and upfront surgery after gastrectomy for gastric adenocarcinoma in a population-based setting.MethodsThis population-based study based on the Finnish National Esophago-Gastric Cancer Cohort included all patients 18 years of age or older undergoing gastrectomy for gastric adenocarcinoma in Finland during 2005–2016. Logistic regression provided odds ratios (ORs) with 95% confidence intervals (CIs), both crude and adjusted for key confounders. Different types of complications were graded based on the Esophagectomy Complications Consensus Group definitions, and major complications were assessed by the Clavien-Dindo scale.ResultsThis study analyzed 769 patients. Neoadjuvant chemotherapy did not increase major postoperative complications after gastrectomy for gastric cancer compared with upfront surgery (OR, 1.12; 95% CI 0.81–1.56). Furthermore, it did not increase pneumonia, anastomotic complications, wound complications, or other complications.ConclusionsNeoadjuvant therapy is not associated with increased postoperative complications, reoperations, or short-term mortality compared with upfront surgery in gastric adenocarcinoma.

The prevalence of common complications among pneumoconiosis patients: a systematic review and Meta-analysis

Objective: To analysis the main types and prevalences of complications among pneumoconiosis patients, and to provide scientific basis for the prevention and treatment of pneumoconiosis. Methods: In January 2023, literatures on pneumoconiosis complications published before December 31, 2022 in China National Knowledge Infrastructure (CNKI), Wanfang Database, Chinese Science & Technology Journal Database (VIP), PubMed and Web of Science were systematically searched. Literatures were selected according to inclusion and exclusion criteria, and relevant data were extracted. Quality assessment tool was used to evaluate the quality of the articles for this study. The combined prevalence of complications among pneumoconiosis patients was calculated by R 4.1.1 software. Subgroup analysis was carried out to explore the origin of heterogeneity. Results: Sixty-four eligible articles were selected from 2276 literatures related to pneumoconiosis and its complications. The combined prevalence of complications among pneumoconiosis patients was 21.1% (95% CI: 16.0%-26.3%, I(2)=99.9%). The combined prevalence of chronic obstructive pulmonary disease (COPD) was 26.4% (95%CI: 17.3%-35.6%, I(2)=97.1%), which was the highest among different types of complications among pneumoconiosis patients. Subgroup analyses revealed that the combined prevalence of tuberculosis among pneumoconiosis stage Ⅰ, Ⅱand Ⅲ were 13.8% (95%CI: 10.5%-17.2%, I(2)=99.6%), 18.4% (95% CI: 14.9%-22.0%, I(2)=99.3%) and 37.3% (95% CI: 30.7%-44.0%, I(2)=99.1%), respectively, showing a corresponding increasing tendency (P<0.05). The combined prevalence of tuberculosis among coal worker's pneumoconiosis patients was 12.9% (95% CI: 6.4%-19.3%, I(2)=97.9%), while the combined prevalence of tuberculosis among silicosis patients was 13.9% (95%CI: 10.0%-17.8%, I(2)=96.9%) . Conclusion: The prevalence of pneumoconiosis patients combined with different types of complications is high, and its prevalence increases with the severity of pneumoconiosis.

Medico-legal evaluation of burn trauma injuries. Epidemiological features and predictors of mortality and other adverse outcomes

Introduction: Burn trauma is a devastating, life-threatening public health issue responsible for significant morbidity and mortality. Developing countries suffer more from the medical, psychological, and economic consequences of burns. The current study aimed to investigate the medicolegal aspects of burn trauma by identifying the epidemiological factors and injury characteristics associated with increased risk of mortality, intentional infliction, and different types of complications. Methods: A prospective cross-sectional study was conducted enrolling the burn trauma patients admitted to Burn Unit, Tanta University Hospital, Egypt over one year. Results: The current study was conducted among 138 burn trauma patients with a case fatality rate of 13.8 %. Of them, 5.8 % were victims of intentional burns, 44.9 % were complicated, and the length of hospital stay ranged between one day and 52 days. Patients aged less than 10 years constituted about 33.3 %. The burn trauma was the highest in June, May and March. Intentionally exposed patients, patients with third-degree burns affecting the head, neck and trunk and those with burns involving a total body surface area (TBSA) of more than 33 % were at high mortality risk. Intentional burns were induced mainly by flame (100 %) and characterized by high severity (TBSA = 85 % and 87.5 % third-degree burns). Intentional burns involved mainly the trunk (p = 0.002) and external genitalia (p = 0.022). The involved TBSA and the highest burn degree were significant predictors of mortality with an excellent area under curves of 0.956 and 0.870, respectively and (p < 0.001). The TBSA of more than 17 % and the burn degrees above the second were significant predictors of in hospital complications (p < 0.001). Daytime intentional burns, burns involving the upper extremities and face, deep and widely distributed burns, and infected wounds were associated with a significant need for surgical treatments. The median length of hospital stay was ten days, primarily attributed to the in hospital complications (p = 0.02). Conclusion: A high degree of vigilance and accurate assessment of burn size, depth and distribution with meticulous interpretation of the mechanism of infliction are central not only for treatment interventions but from the medicolegal point of view.

Implant Supported Fixed Prostheses and Bruxism: An Overview

The bruxism is an oral parafunction characterized by occlusal overload contacts. The global management of bruxism patients may require a prosthetic rehabilitation whether it is fixed, removable or more recently implant-supported prostheses. The aim of our literature review is to evaluate the survival rate of implant-supported prostheses in patients with bruxism, to detail the different types of complications, and to develop recommendations to ensure the longevity of this type of prosthesis in this type of patient.

Health State Utility Values for Children and Adolescents with Type 1 Diabetes: A Systematic Review and Meta-analysis.

Type 1 diabetes mellitus (T1DM) is one of the most burdensome chronic diseases in the world. Health utility values are an important tool for quantifying this disease burden and conducting cost-utility analyses. This review aimed to derive a reference set of health utility values for children and adolescents with T1DM. We searched MEDLINE and Embase from inception to March 2023 for health utility values of T1DM children and adolescents (aged ≤18 years) measured using direct and indirect preference elicitation approaches. Utility estimates were pooled by meta-analyses with subgroup analyses to evaluate differences by populations and elicitation approaches. Six studies involving 1276 participants were included in this study. Meta-analysis showed the overall utility value of children and adolescents with T1DM was 0.91 (95% CI 0.89-0.93). The utility value of T1DM children and adolescents with complications was 0.90 (95% CI 0.88-0.92), which was lower than those without complications (0.96, 95% CI 0.95-0.97). The utility value of children (aged <13 years) was higher than adolescents (aged 13-18 years) (0.90 vs. 0.85). The utility value measured by the EQ-5D-3L (0.91) was higher than the HUI3 (0.89), the SF-6Dv1 (0.83), and the time trade-off (0.81). The parent proxy-reported was similar to the patient self-reported (0.91 vs. 0.91). This study developed a reference set of pooled utility estimates for children and adolescents with T1DM, which is helpful for understanding the overall health status of T1DM and conducting economic evaluations. Further studies are needed to explore the utilities of T1DM with different types of complications.

THERAPEUTIC EFFECT OF USING AUTOLOGOUS PLATELET CONCENTRATE IN VITRECTOMY FOR MACULAR HOLE: A Systematic Review and Meta-Analysis.

To summarize the current evidence regarding the therapeutic effect of using autologous platelet concentrate (APC) in vitrectomy for macular hole (MH). The PubMed, Web of Science, and Embase databases were searched according to the PROSPERO protocol (CRD42022366202). Controlled trials comparing whether APC was used in the vitrectomy of MH were included. The primary outcome was the closure rate of MH and postoperative best-corrected visual acuity, and the secondary outcome was the incidence of different types of complications. Seven studies that included 634 eyes were eligible. For the primary outcome, the usage of APC significantly improved the closure rate of MH in vitrectomy (odds ratio [OR] = 5.34, 95% confidence interval, 2.83-10.07, P < 0.001). Postoperative visual acuity did not significantly differ between the APC group and similar baseline controls (SMD = -0.07, 95% confidence interval, -0.35 to 0.22, P = 0.644). For the secondary outcome, using APC did not result in additional complications regarding postoperative retinal detachment or the recurrence of MH. The use of APC in vitrectomy was associated with a superior closure rate of the hole and no additional complications; therefore, it is effective and safe in MH surgery.

Maximum safety and minimum risk: midline access gained by a nurse-led Vascular Access and Infusion Team

Abstract Aim. The aim of the study was to conduct a retrospective analysis of cannulations done under ultrasound guidance by the Vascular Access and Infusion Team using the Seldinger technique. Material and methods. This observational study was retrospective in nature. Analysis was carried out of 82 cannulation charts reporting procedures from March to August 2022 at the University Clinical Centre of the Medical University of Warsaw. Results. Midline access was gained in 86 patients with a success rate of 95.3% (n=82). Cannulation by nurses was performed in 93% (n=80) of the patients. The procedure required an average of 1.62 attempts. The most frequently cannulated veins were the basilic (72%, n=59) and brachial (14.6%, n=12) ones. MC removal in 40.2% (n=33) of the cases was due to the termination of intravenous therapy, and in 23.4% (n=19) was caused by complications related to infusion management. Conclusions. Implantation of midline catheters in patients, including those with difficult intravenous access, can be done eff ectively with a minimum number of cannulation attempts. Maintaining midline catheters for the entire duration of therapy is challenging due to potential complications and requires rigorous care during their use. A detailed analysis of possible complications distinguishing between diff erent types of complications and continuous improvement of observation protocols and appropriate management is advisable. It is also advisable to plan and conduct an observational study in the area of retrospective analysis.

Complete Mesocolic Excision (CME) versus Conventional RT Hemicolectomy (CRH) in Patients with Right Sided Colon Cancer: A Systematic Review and Meta-Analysis

Abstract Background We live in an era with improved worldwide average living standards and increased access to adequate healthcare that has considerably improved the diagnosis and treatment of diseases. These measures have had an impact on average life expectancy in most regions of the world. Aim of the Work The aim of this study is to perform a systematic review and meta-analysis to investigate safety and long-term out- comes of Complete Mesocolic Excision (CME) Versus Conventional RT Hemicolectomy (CRH) in patients with right sided colon cancer. Materials and Methods This study is a systematic review and meta-analysis. Literature search, study design, and data analysis were performed following PRISMA (preferred reporting items for systematic reviews and meta-analyses) guidelines. Five medical databases were used in this research: MEDLINE, Cochrane Database of Systematic Reviews, Scopus, Web of Science, and Embase. The keyword was as follows: ―complete mesocolic excision.‖ I select studies published up to December 2020. I select only articles written in English and we did not include abstracts or unpublished data. After literature search, 30 studies have been recorded. Screening by titles and abstracts led to the identification of 20 possibly relevant articles. Of these records, 8 studies were excluded because patients with distal transverse and/or left colon cancer were also evaluated. Moreover, in 3 studies, only the most recently record was selected. Lastly, 8 studies, published between 2010 and 2020, met inclusion criteria. All selected studies were observational; 4 of them were prospective. Overall, 1762 patients were enrolled in qualitative and quantitative analysis, 700 in the CME group and 1062 in the CRH group. Results Postoperative complications were reported in 9 studies showing that no difference was observed between techniques. Six studies separately analyzed surgical and non-surgical postoperative complications. No significant variation was reported between the 2 groups in the 2 different types of complications (surgical complications OR 1.09, 95% CI 0.72–1.63, p = 0.69, no surgical complications OR 1.37, 95% CI 0.79–2.36, p = 0.26, respectively). No significant difference was al- so observed between the two groups in terms of anastomotic leakage, while a significant negative median was reported for intraoperative bleeding in favor of CME group. 4 studies evaluated the procedure time which was significantly shorter for CRH, although heterogeneity levels among studies was high. The analysis of postoperative length of stay showed no difference between the two groups of patients. Number of lymph node yield was reported in 8 studies. The pooled analysis of 1762 patients found a positive median retrieval of 9.17 in CME group. High heterogeneity among the included studies was detected. Seven studies reported data of 3-year OS with a significant OS benefit in CME group. This data was characterized by moderate between-study heterogeneity. Furthermore, 76.4% of patients undergoing CME surgery were alive at 5 years, compared with 68.2% of CRH. Meta-analysis of 3 studies reporting 5-year DFS con- firmed the significant DFS benefit for patients undergoing CME. No significant heterogeneity was observed between the 3 studies. Conclusion My study confirm that CME with CVL associated with D3 lymphadectomy in right-side colon cancer improved not only staging but also prognosis, particularly in II and III stage; CME was a significant independent predictive factor for disease-specific survival at 3 years and 5 years compared with CRH associated with D2 lymphadectomy. CME is a safe and reproducible procedure with acceptable morbi-mortality.

Comparison of COVID-19 epidemic among Czech dentists and the Czech general population

Dentists are one of the professional groups most at risk for COVID-19 infection. Enhanced protective measures in dentistry have been adopted worldwide; however, it is unclear to what extent they were sufficient. To assess whether the protective measures outweighed the high infection risk, we compared COVID-19-related data between Czech dentists and the general Czech population. The data was obtained through a survey study attended by 15.8% of Czech Dental Chamber members. Data of the general population were acquired from the Czech Ministry of Health database. By the end of May 2022, COVID-19 full vaccination and 1st booster dose rates among study participants were 85.8% and 70.1%, respectively, which is significantly higher (p < 0.0001) compared to the Czech general population aged over 24 years (74.9% and 49.4%, respectively). To the same date, PCR/Antigen test verified COVID-19 prevalence among participants was 41.7%, and 49.9% among the general population (p < 0.0001). Prevalence and reinfection rates among individuals who received the 1st booster were significantly lower than among individuals without the booster or full vaccination (p < 0.0001). Persons who received the booster showed a faster return to work, shorter and different types of complications. Willingness to future vaccination was positive among 79.7% of respondents. Mandatory vaccination for healthcare workers and the general population was supported by 62.0% and 49.0%, respectively. The results showed that the high risk of COVID-19 infection associated with dentistry did not lead to higher COVID-19 prevalence among respondents compared to the general population.

Abdominal aortic aneurysm surgery with a modern method - is there anything to fear?

Background: Endovascular surgery for abdominal aortic aneurysms using a stent graft is the modern method of supplying these life-threatening lesions in large arterial vessels. In recent years, there have been significant improvements in the technique of performing these procedures, despite which complications are still common. In order to make progress in dealing with this problem, it is important to understand in which areas of the treatment strategy appropriate changes have not yet been implemented. Various clinical cases that describe post-operative complications of stent-graft surgery, types of post-operative complications and methods of dealing with the complication that has occurred should be analysed. And also other research papers relating to this topic. The first step is to deepen the knowledge of existing post-operative complications and the types of complications that can occur after stent-graft implantation into the abdominal aorta, as well as contemporary methods of treating complications that have already arisen.&#x0D; Aim of the study: The aim of this study is to present the incidence of complications after endovascular surgery for abdominal aortic aneurysms using a stent graft, the repair methods used when a complication occurs, the types of complications and their different kinds based on a review of the literature.&#x0D; Material and methods: A literature review was conducted in English-language databases, based on original articles and case reports, on post-operative complications of abdominal aortic stent-graft surgery, together with treatment methods and different types of complications arising from this procedure published between 2022 and 2023. Using the keywords: "abdominal aortic stent-graft" and "complications".

Retracted: Comparative Analysis of Early Clinical Features and Complications of Different Types of Acute Pancreatitis.

[This retracts the article DOI: 10.1155/2022/3771610.].

Congenital bilateral scrotal agenesis with bilateral cryptorchidism: a case report

Congenital bilateral scrotal agenesis is very rare anomaly and characterized by the absence of scrotal rugae. It may be associated with other extra-genital anomalies as a part of a syndrome. Etiology is unknown but may be due to primary failure of labioscrotal folds development or secondary to localized 5-alpha-reductase type 2 deficiency. Various surgical techniques used for neoscrotum construction with different types of complications. In index case, we performed bilateral orchidopexy without creating neoscrotum.

Complications after abdominal surgery

Complications after abdominal surgery are often seen in emergency departments. Many postoperative complications (e.g., infections, abscesses, hematomas, and active bleeding) are common to all types of surgery; others are specific to different types of surgery. Computed tomography (CT) is the technique normally used to diagnose postoperative complications.This article reviews the changes that occur after some of the most common abdominal interventions that can be mistaken for pathological processes, the findings that can be considered normal after surgical intervention, and the most common early complications. It also describes the optimal protocols for CT studies depending on the different types of complications that are suspected.

Cranioplasty-Autologous Bone graft Vs Titanium Mesh

Background: Cranioplasty (CP) is a neurosurgical procedure performed after decompressive craniectomy using autologous bone graft or various artificial materials. Aim: To find differences in complications between patients who underwent CP using an autologous bone flap versus a titanium mesh as well as to identify significant risk factors for post-CP complications Study Design: Comparative cross-sectional study. Methodology: A total of 46 patients were included in this study, out of which 37 were males (80.4%) and 9 were females (19.6%). All patients underwent cranioplasty using titanium mesh or autologous bone graft. Results: Comparison of outcome between autologous graft and titanium implant was done. In 45.7% patients, autologous bone graft was used while titanium implant was used in 54.7%. 23.9% patients had developed different types of complications in both groups, out of which 81.9% were from autologous group and 18.1% belonged to titanium graft group. Surgical site infection was noted in 18.1% of patients (equally) in both groups. Craniopalsty infection was noted in 45.4% patients who underwent autologous graft. Hematoma was encountered in 2 patients; both with autologous bone graft and none in patients who had titanium mesh cranioplasty. Removal of autologous bone graft was done in one patient whileremoval was not done in the other arm of study. Bone resorption was seen in five patients, all of which had autologous bone graft. Learning curve is that this technique be followed by neurosurgeons for better outcome. Practical implicatio Titanium mesh cranioplasty is a technique to be followed by junior neurosurgeons for learning and good outcome, decrease duration of hospital stay and preservation of precious resources of hospital. Conclusion: Cranioplasty in which titanium mesh is used is superior to autologous bone grafting as it has lessercomplications. Keywords: Autologous graft, bone resorption, cranioplasty, hematoma, infection, titanium mesh.

Complications of Different Types of Cranioplasty and Identification of Risk Factors Associated with Cranioplasty at a Tertiary Care Centre: A Prospective Observational Study

Abstract Objective Decompressive craniectomy (DC) is an urgent procedure which is done to decrease intracranial pressure. A study of the complications would suggest measures to improve the care. This study was focused on analyzing the complications after cranioplasty (CP) and to identify risk factors that may be associated with the failure of the procedure. Method: This study was conducted over 41 months at level-1 trauma center and medical college. It included patients undergoing CP for a defect arising out of previous DC or inability to replace the bone flap (Glasgow Coma Scale &gt; 13, size &gt; 5 cm, without surgical site infection). All patients underwent CT imaging before and after the procedure. The CP technique largely depended on the patients, based on the cost of prosthesis and availability. Result: Hundred patients were included in the study. Postoperatively, total 22 patients suffered complications of which few had more than one complication. Titanium implant appeared to be a better implant, with no complication (p &lt; 0.05). Complication was common in younger age group, chemically cured PMMA (polymethyl methacrylate) and ethylene oxide) sterilized bone flap). Complications were higher among patients with multiple comorbidity and stroke patients. Conclusion: Titanium flap had no complication and in case of autologous abdominal subcutaneous flap, apart from bone flap absorption, patients had no major complication. Therefore, both implants are preferred implants for CP. Heat-cured PMMA can be used in case of nonavailability of a better option, as it is economical feasible and can be molded at any dental lab.

Seizure-related complication rate in a residential population with epilepsy and intellectual disability (ECOMRAID-trial)

IntroductionThe aim of the ECOMRAID trial (Epileptic seizure related Complication RAte in residential population of persons with epilepsy and Intellectual Disability) was to study seizure-related complications (status epilepticus, respiratory complications, or other severe complications) in people with epilepsy and intellectual disability living in a residential setting. The results of the present study are a prerequisite for performing a prospective study into the effectiveness of nocturnal surveillance patients with high risk for Sudden unexpected death in epilepsy (SUDEP). Material and methodsA retrospective study was conducted in three general residential care institutions and one residential specialized epilepsy clinic. In this 5-year cohort, we collected the following data: age (at inclusion and in case of death), sex, type of residential care, different types of complications, rescue/emergency medication administration, transfers to another department (internal midcare / monitoring unit or general hospital) and a self-designed SUDEP risk score. Our primary research questions were to assess the number of patients who experienced seizure-related complications and their individual complication rates. The secondary research questions were to document the relationship of these complications with the SUDEP risk score, with the type of residential living, and with the frequency of interventions by caregivers. ResultsWe included 370 patients (1790 patient-years) and in 135 of them, we found 717 seizure-related complications. The following complication rates were found: all complications: at 36%, status epilepticus: at 13%, respiratory complications: at 5%, and other complications at 26%. In residential care institutions, we found fewer patients with complications compared to the specialized epilepsy clinic (all complications 24% vs 42%, OR 0.44, p < 0.01; status epilepticus 5% vs 17%, OR 0.27, p < 0.01; other: complications 19% vs 30%, OR 0.56, p < 0.05). In residential care institutions, we found more “other complications” than in the specialized epilepsy clinic (89% vs 71%, OR 3.13, p < 0.0001). The annual frequency of all complications together was higher in residential care institutions (range 0 to 21 vs 0 to 10, p < 0.05). Rescue medication was given to 75% of the patients, but more often in the specialized epilepsy clinic (median 2.6 vs 0.5 times/patient/year, p < 0.001). In the specialized epilepsy clinic, more patients were transferred to a midcare / monitoring unit or general hospital (56% vs 9%, OR 13.44, p < 0.0001) with higher yearly frequencies (median 0.2 vs 0.0, p < 0.001). There were no reported cases of SUDEP. The median SUDEP risk score was higher in the specialized epilepsy clinic (5 vs 4, p < 0.05) and was weakly correlated with the status epilepticus (ρ = 0.20, p < 0.001) and (total) complication rate (ρ = 0.18, p < 0.001). ConclusionWe found seizure-related complications in more than one-third of the patients with epilepsy and intellectual disability living in a residential setting over a period of 5 years. The data also quantify seizure-related complications in patients with epilepsy and intellectual disability.