Event Abstract Back to Event Modeling neural dependencies with Poisson copulas Pietro Berkes1*, Frank Wood2 and Jonathan Pillow2 1 Brandeis University, United States 2 University College London, United Kingdom The coding of information by neural populations depends critically on the statistical dependencies between neuronal responses. At the moment, however, we lack of a simple model that can simultaneously account for (1) marginal distributions over single-neuron spike counts that are typically close to Poisson; and (2) joint distributions over the responses of multiple neurons that are often strongly dependent. Here, we show that both marginal and joint properties of neural responses can be captured using Poisson copula models. Copulas are joint distributions that allow random variables with arbitrary marginals to be combined while incorporating arbitrary dependencies between them. Different copulas capture different kinds of dependencies, allowing for a richer and more detailed description of dependencies than traditional summary statistics, such as correlation coefficients. We explore a variety of Poisson copula models for joint neural response distributions, and derive an efficient maximum likelihood procedure for estimating them. We apply these models to neuronal data collected in the macaque pre-motor cortex, and quantify the improvement in coding accuracy afforded by incorporating the dependency structure between pairs of neurons. Conference: Bernstein Symposium 2008, Munich, Germany, 8 Oct - 10 Oct, 2008. Presentation Type: Poster Presentation Topic: All Abstracts Citation: Berkes P, Wood F and Pillow J (2008). Modeling neural dependencies with Poisson copulas. Front. Comput. Neurosci. Conference Abstract: Bernstein Symposium 2008. doi: 10.3389/conf.neuro.10.2008.01.031 Copyright: The abstracts in this collection have not been subject to any Frontiers peer review or checks, and are not endorsed by Frontiers. They are made available through the Frontiers publishing platform as a service to conference organizers and presenters. The copyright in the individual abstracts is owned by the author of each abstract or his/her employer unless otherwise stated. Each abstract, as well as the collection of abstracts, are published under a Creative Commons CC-BY 4.0 (attribution) licence (https://creativecommons.org/licenses/by/4.0/) and may thus be reproduced, translated, adapted and be the subject of derivative works provided the authors and Frontiers are attributed. For Frontiers’ terms and conditions please see https://www.frontiersin.org/legal/terms-and-conditions. Received: 13 Nov 2008; Published Online: 13 Nov 2008. * Correspondence: Pietro Berkes, Brandeis University, Waltham, United States, berkes@brandeis.edu Login Required This action requires you to be registered with Frontiers and logged in. To register or login click here. Abstract Info Abstract The Authors in Frontiers Pietro Berkes Frank Wood Jonathan Pillow Google Pietro Berkes Frank Wood Jonathan Pillow Google Scholar Pietro Berkes Frank Wood Jonathan Pillow PubMed Pietro Berkes Frank Wood Jonathan Pillow Related Article in Frontiers Google Scholar PubMed Abstract Close Back to top Javascript is disabled. Please enable Javascript in your browser settings in order to see all the content on this page.
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