The article is devoted to understanding the significance of Renaissance literature in the Czech Republic. Humanistic activity, which originated in the Czech Republic, occupies an important place in the history of the Slavic Renaissance. In the XV century, hatred of papal domination and the struggle for independence intensified in the Czech Republic, where the activities of the Hussites flourished. Czech literature of this era had didactic and religious content. The economic development of the state has changed the situation of cities. Nevertheless, this allowed Italian humanism to become more widespread. The Hussite movement played an important role in the struggle against foreign domination and feudal arbitrariness. But since this act was shrouded in a religious veil, the patriotic psalms were also in a religious spirit, they were performed accompanied by music. The struggle of the Hussites against the Catholics and the reform movements of this period cannot distinguish the main features of the Czech literature of the Renaissance. The main features of the Renaissance are vividly manifested in world culture, based on the foundations of ancient society, in art reflecting the achievements of the body and soul, depicting the joys of life. The first stage of the development of Czech humanism corresponds to the period when Petrarch was in Prague (1356). Since that time, interest in the "new style" of Italian poetry begins to manifest itself. The article also argues that the historical and political events taking place in Czech society during that period also had a great influence on the development of literature.