Introduction: Endometrial stromal sarcoma (Ess) is a rare malignancy arising from the endometrial stroma. the majority (90%) of patients present with abnormal uterine bleeding (AUb) followed by mass per abdomen and pelvic pain. However, rarity of this tumor limits the clinician to consider it even as a differential diagnosis despite of having its typical symptoms and only diagnosed by biopsy as a surprise. On analysis of age of presentation, clinical findings and various diagnostic modalities, endometrial stromal sarcoma (Ess) mimics other disorders such as leiomyoma, leiomyosarcoma and endometrial polyp. the diagnostic dilemma continues even on gross and microscopic features of Ess and above mentioned disorders. the role of immunomarkers like cD10, desmin, h-caldesmon, etc. has evolved for specific diagnosis. case report: A 60-year-old female was presented with a complaint of postmenopausal bleeding underwent hysterectomy with a provisional diagnosis of submucous myoma and histopathological examination revealed this as endometrial stromal sarcoma. conclusion: Endometrial stromal sarcoma is a rare
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