Diagnosis Of Splenic Marginal Lymphoma Research Articles

Discordant lymphoma: report of one case and review of literature

Objective To investigate the clinical characteristics, diagnosis, treatment and prognosis of discordant lymphoma. Methods The clinical data of one patient with discordant lymphoma at the PLA Strategic Support Force Characteristic Medical Center were retrospectively analyzed, and the related literatures were reviewed. Results The patient was treated for thrombocytopenia and the examination showed splenomegaly. After hormone treatment, the platelet rebounded and thrombocytopenia occurred during hormone reduction. Splenectomy was performed. Postoperative pathological diagnosis of splenic marginal lymphoma was made and observed. Axillary lymph node enlargement occurred nine months later. Pathological diagnosis of diffuse large B-cell lymphoma was made by using lymph node biopsy, and the disease condition was alleviated after immunotherapy combined with chemotherapy. Conclusions Discordant lymphoma is rare and shows no special clinical manifestations. Its diagnosis should rely on pathological examination. Immunotherapy combined with chemotherapy may be more effective. Key words: Lymphoma, B-cell, marginal zone; Lymphoma, large B-cell, diffuse; Discordant lymphoma; Pathogenesis; Diagnosis; Prognosis

Neck discordant lymphoma: report of one case and review of literature

目的 探讨不一致性淋巴瘤的临床病理学特征。 方法 结合临床、影像学、病理形态和免疫组织化学检测，对1例不一致性颈部淋巴结结节硬化型霍奇金淋巴瘤及甲状腺左叶及峡部弥漫大B细胞淋巴瘤进行病理分析，并复习相关文献。 结果 患者，女性，46岁，以甲状腺双叶实性肿物及双颈部多发淋巴结肿大为首发症状，手术切除甲状腺双叶及颈部淋巴结，术后病理诊断为不一致性淋巴瘤，右颈及部分左颈部淋巴结为经典型霍奇金淋巴瘤，甲状腺左叶及峡部为弥漫大B细胞淋巴瘤。 结论 不一致性淋巴瘤较为罕见，表现形式多样，且发生的解剖部位不同，应引起临床和病理医师的足够重视，其治疗方案及预后判断由恶性程度高的肿瘤类型决定。