Diagnosis Of Rare Tumors Research Articles

Primary Hepatic Neuroendocrine Tumor and its Metastasis to Breast; Case Report of an Unusual Malignancy

Introduction: Neuroendocrine tumors (NETs) are rare tumors with varied clinical presentations. Entero-pancreatic and respiratory systems are usually involved but it can also affect unusual sites like the liver.
 Purpose: This paper presents a case of a 45 years female who developed progressive and disabling symptoms of mass effect and carcinoid but remained undiagnosed for many years due to extremely low suspicion of such a tumor in liver.
 Methods: Diagnosis was made after extensive radiological, histopathological, and biochemical investigations. By that time, disease had spread to her breast which is also not a typical feature of NETs.
 Findings: Diagnosis of rare tumors at an unusual site is challenging and requires high clinical suspicion and appropriate workup.

Looks Can Be Deceiving

BACKGROUND: A thorough history, physical examination, and comprehensive work-up is important to differentiate the etiology of a cervical mass in unusual cases. CASE: A 36-year-old white female presented with heavy vaginal bleeding, pelvic pain, and an exophytic cervical mass extending to the anterior vaginal wall. She underwent cold knife cone with biopsies of the vagina. Pathology revealed dysgerminoma. Computed tomography of the abdomen and pelvis demonstrated pelvic lymphadenopathy, an enlarged uterus, and a 4 cm complex ovarian mass. The final pathology helped establish the true diagnosis. CONCLUSION: The accurate diagnosis of rare tumors requires a broad differential diagnosis and careful review of the pathologic findings and clinical scenario.