Diagnosis Of Polycystic Kidney Research Articles

Congenital giant megaureter associated with ipsilateral multicystic dysplastic kidney in newborn

Congenital giant megaureter presents as abdominal mass and impose diagnostic difficulties. It can be associated with other upper urinary tract anomalies. A female newborn with antenatal diagnosis of polycystic kidneys was admitted at birth due to lower abdominal mass. Ultrasound and CT scans diagnosed a multiloculated cystic lesion in the mid and lower abdomen along with right side multicystic kidney. At laparotomy, an extaperitoneal, lobulated cystic swelling was found due to rightside giant megaureter. Its lower end was of normal caliber and orthotopic. End cutaneous ureterostomy was done. Intravenous urogram and isotope renograms showed nonfunctioning right kidney. She also had grade II vesicoureteral reflux on left side. Child suffered urinary infection twice. At 9m age, right nephroureterectomy was done. Histopathologic examination was consistent with cystic renal dysplasia and dilated ureter. This is the first case report of giant megaureter associated with ipsilateral multicystic dysplastic kidney in newborn.

Immune Thrombocytopenic Purpura Following Acute Lymphoblastic Leukemia in Remission

This is a case report of a 19 year old male undergraduate with a background diagnosis of polycystic kidney and hypertension. Two years thereafter, he was diagnosed to have ALL L1 morphology which responded to induction chemotherapy using Vincristine and Prednisolone (V+P). He later proceeded to India where the same diagnosis was confirmed and molecular study pointed to standard risks ALL. Following successful Induction Remission and Consolidated therapy, he was sent to us to follow up his maintenance therapy. Patient defaulted severally. He represented with severe thrombocytopenia and thrombocytopenic bleeding with blood film and marrow being devoid of blasts but rather marrow showed numerous smooth, non-budding, cytoplasmic basophilic megakaryocytes in keeping with ITP. He responded rapidly to steroid therapy. Patient remains stable as at now after 3 months of steroid therapy. ITP following ALL in remission is an uncommon occurrence, hence this report.

5. Diagnosis of Polycystic Kidney

多発性嚢胞腎は両側腎臓，肝臓を中心に多発性の嚢胞が出現し，腎機能が徐々に低下する遺伝性疾患で，同時に脳・心血管系の異常，腸管憩室などの合併症を伴う全身疾患である．これまでは腎嚢胞の拡大を抑制する治療がないため，腎障害が進行するまで放置されることが多かったが，責任遺伝子が発見されて以来，腎嚢胞の形成・拡大の病態が解明されてきた．降圧治療に加え，V2受容体抑制薬の治験など新たな治療が検討されている．

Prenatal Diagnosis of Polycystic Kidney Disease with Hydroureter: A Comparison of Magnetic Resonance Imaging with Two-and Three-Dimensional Ultrasound

Objective: To compare magnetic resonance imaging (MRI) with 2-dimensional (2D) and 3-dimensional (3D) ultrasound for the prenatal diagnosis of a polycystic kidney with hydroureter. Case Report(s): A 30-year-old Taiwanese women, gravida 2, para 0, was referred to our antenatal clinic under the impression of fetal bowel obstruction at 30-weeksi¦ gestational age. Two- dimensional (level II) ultrasound was performed at our institutions and a polycystic kidney was impressed. Hydroureter was suspected, but dilatation of the bowel could not be ruled out. 3-D ultrasound confirmed the diagnosis of polycystic kidney but hydroureter or bowel obstruction remained undetermined. A T2-weighted MR image which was obtained in 3 orthogonal planes confirmed the fetal polycystic kidney combined with hydroureter. Postnatal pediatric renal sonography demonstrated left cystic kidney disease with hydroureter. Tc-99m DTPA radionuclide study revealed marked impaired left renal function. Recurrent urinary tract infection and fever in the infant were noted, and the infant received a left nephroureterectomy at the age of 3 months old. Surgical findings included polycystic kidney and obstruction of the urinary tract at the junction of the renal pelvis and the ureter. The pathology report demonstrated multicystic kidney disease, megaloureter, and hydroureter. The postnatal diagnosis proved the antenatal diagnosis by MRI. Conclusion(s): We found that coronal scanning of the fetus could be performed more easily by magnetic resonance imaging. The MRI scan can provide better demonstration of hydroureter than is possible with ultrasound antenatally.

Roentgenologic diagnosis of polycystic kidney and medullary sponge kidney.

Roentgenologic diagnosis of polycystic kidney and medullary sponge kidney.

Hepatonephrotomography. Its value in the diagnosis of polycystic kidney and liver disease.

Hepatonephrotomography. Its value in the diagnosis of polycystic kidney and liver disease.

The Roentgen Diagnosis of Polycystic Kidneys

The Roentgen Diagnosis of Polycystic Kidneys