Diagnosis Of Osteoblastoma Research Articles

Osteoblastoma of the temporal bone – A familiar tumour at an uncommon site

Osteoblastoma is a benign bone tumour arising from the non-odontogenic epithelium. This tumour predominantly affects the vertebral column and long tubular bones such as the femur and tibia. Herein, we report a case of Osteoblastoma affecting temporal bone. Radiologically, it was thought to be an intraosseous meningioma, hemangioma, or eosinophilic granuloma. Histopathological examination of the tumour showed woven bone arranged in sheets and micro trabecular array, rimmed by a single layer of osteoblast, surrounded by lamellar bone. Intertrabecular spaces were composed of richly vascular fibrotic stroma, consistent with the diagnosis of osteoblastoma.

An unusual case of osteoblastoma in shaft of fibula: Case report

Background: Osteoblastoma and osteoid osteoma are rare, benign, bone forming tumours. This is a rare case of osteoblastoma in shaft of a long bone, in an unusual location, causing a therapeutic dilemma.Aims & Objectives: Osteoblastoma and osteoid osteoma are closely related lesions with similar histological patterns and indistinguishable radiographic features. This case was studied to understand the similarities and differentiating features of the two. Methods: Here was a case of 18 years old male patient with history of bony swelling and pain in his right leg which relived with a dose of Aspirin. After thorough examination plain radiographs and CT scan of the part was done. Surgical excision of the lesion was done and sent for histopathology examination. Patient was adequately treated and followed up at 1,3,12 & 18 months post operatively to assess the involved site and evidence of recurrence. Result: Plain radiographs and CT scan of the part involved provisionally diagnosed the lesion as osteoid osteoma. Histopathology examination found features suggestive of osteoid osteoma and a diagnosis of osteoblastoma was given, considering the size of the nidus. Patient was followed up at 1,3,12 & 18 months post operatively and there was no evidence of recurrence. Conclusion: Osteoblastoma and osteoid osteoma were classified as variants of single tumour type based on a number of shared histological and radiographic features. Most significant difference between the two lesions is the size of the nidus. Thus, there may be transitional zone of uncertainty in establishing the correct diagnosis. Osteoid osteoma must be considered a differential diagnosis when the lesions are large and in unusual sites like long bones.

OSTEOBLASTOMA OF THE JAW IN A CHILD

A 10-year-old girl complained of an asymptomatic swelling, with approximately 3 months, on the left side of her jaw. No history of dental pain, bleeding, paresthesia, or trauma was described. Her medical history only revealed a G6 PD deficiency. A physical examination disclosed a localized hard bone swelling, with approximately 3 cm x 2 cm in diameter, localized on the left mandible. The overlying mucosa was normal in appearance, color and temperature and there was no motor or sensory deficit. No regional lymphadenopathy or intraoral modifications were noticed. A computed tomography prescribed revealed a poorly-defined expanding lesion with mixed pattern of radiolucency and radiopacity in the posterior body of the mandible. After a negative puncture, an incisional biopsy was taken and a diagnosis of osteoblastoma was rendered. A wide local excision of the tumor was performed and after 6 months the patient is disease free with no associated functional or neurologic deficit.

BLOCK RESECTION OF LUMBAR OSTEOBLASTOMA. PRESENTATION OF A CASE AND BIBLIOGRAPHICAL UPDATE

ABSTRACT Objective: To present the clinical case and update the bibliography. Methods: A male patient, 24 years of age, sought treatment for right lumbosciatalgia of 3 years of evolution with topography L5 and motor deficit (M4). The radiograph showed a radiopaque lesion between the fourth and fifth lumbar vertebrae, with right pedicle effacement of L4. The tomography identified a lytic lesion, partially surrounded by sclerosis with a central nest of 3 centimeters in diameter located in the right pedicle with involvement of the transverse apophysis and reaction of the intertransverse space (Enneking 3). It was complemented by magnetic resonance and bone scintigraphy. The percutaneous biopsy guided by tomography yielded a diagnosis of osteoblastoma and foci of necrosis. A radical block resection was performed with clear tumor margins and instrumented stabilization. Results: After the surgical treatment, the patient evolved favorably, reversing the motor deficit. The anatomopathological study of the specimen confirms the preoperative diagnosis. Discussion: Intralesional resection may be an option in Enneking stage 2. In Enneking stage 3, a percutaneous diagnostic biopsy may be useful, and block resection is the preferred definitive treatment. Conclusions: The management of spinal osteoblastoma requires an exhaustive clinical-imaging analysis. Block resection with clear margins is preferred in advanced cases for management and to decrease the risk of recurrence. Level of Evidence IV; Case seriesh.

Clinics in diagnostic imaging (174). L5 vertebral superior facet osteoblastoma (OB).

A 25-year-old man presented with chronic low back pain and occasional radiation to the right lower limb. Magnetic resonance imaging and computed tomography (CT) of the lumbar spine showed an osteolytic expansile lesion with a central sclerotic nidus in the right superior facet of the L5 vertebra and surrounding marrow oedema. The diagnosis of osteoblastoma was made based on imaging findings and confirmed after CT-guided biopsy. Radiofrequency ablation of the lesion was successfully performed. The patient tolerated the procedure well and showed symptomatic relief. The imaging features and management of osteoblastoma are discussed.

Benign osteoblastoma of the mandible

Osteoblastoma, a rare osteoblastic tumor, constitutes approximately 1% of all primary bone tumors. It is characterized by osteoid and bone formation with the presence of numerous osteoblasts. A 24-year-old female presented with a chief complaint of a painless swelling beneath the mandible, which was growing during the past 3 years. Radiological picture disclosed a well-circumscribed lesion with patchy radiopaque internal structure. After complete excision, the histopathological diagnosis was a benign osteoblastoma of the mandible. Differential diagnosis and immunohistochemical features are potentially useful for refining diagnosis of osteoblastoma.

Destructive Cervical Spine Osteoblastoma at C5 in a Young Patient Initially Presenting with Quadriparesis: Case Report and Review of the Literature

BackgroundOsteoblastomas are rare benign bone tumors that are mostly found in the posterior spinal elements; about 20% are located in the cervical spine. ObjectiveThe case of a destructive cervical osteoblastoma at C5 is reported in a 19-year-old man who initially presented with spastic quadriparesis. Case ReportA 19-year-old man was self-referred, reporting symptoms in keeping with a progressive spastic quadriparesis, which had suddenly developed 6 days earlier. Preceding symptoms included mild non-specific neck pain for 3 weeks. The patient was afebrile, and no ambulatory X-ray study had been performed until the time of referral. A cervical spine computed tomography (CT) scan revealed a lytic lesion involving the spinal process and the pedicles of the C5 vertebra. Cervical spine magnetic resonance imaging performed on an inpatient basis revealed a well-circumscribed, destructive lesion of the C5 vertebra, measuring approximately 3 cm. The spinal cord was significantly compressed. The patient underwent open surgical resection of the tumor through a midline posterior approach. Histopathology of the tumor specimen was in keeping with a diagnosis of osteoblastoma. ConclusionNeuroimaging should be performed with either conventional plain X-ray study, which seems to be sufficient in patients presenting with non-specific symptomatology related to cervical spine damage, or with advanced techniques in the case of patients with persistent neck pain or neurological deficit.

Clinical-morphological peculiarities of osteoblastomata and their differential diagnosis

Osteoblastoma (OB) is a rare benign osteogenic tumour formed by interwoven with one another osteal trabeculae, which are surrounded by a lot of osteoblasts. The purpose of the present work was to elucidate the nomenclature and main clinical-visualizing pathohistologic features of OB as a true osteogenic tumor, as well as some aspects of its differential diagnosis with other osteogenic tumors and tumor-like bone lesions. Forty-three cases of biopsies obtained from 39 patients with OB served as the material for this research. The article contains data about clinical-visualizing features of OB (X-ray and CT), its macropathology, histopathology and differential diagnosis, as well as clinical-morphological gradations of osteogenic tumours. It was found out that OB passed clinically as an active or aggressive form with signs of a local destructive growth and inclined to relapsing in case of its incomplete removal, but very seldom it subjected to malignancy. OB often becomes an object of complicated differential-diagnostic solutions, which are possible only with application of both clinical-visualizing and histological methods with priority of the latter ones. The nosological units for differential diagnosis of OB should include the following ones: osteoid-osteoma, ossifying periostitis, chronic osteomyelitis (corticolitis-periostitis), osteoblastoma-like central osteosarcoma with a low grade of malignancy.

Utility of immunohistochemical analysis for cyclooxygenase 2 in the differential diagnosis of osteoblastoma and osteosarcoma

Utility of immunohistochemical analysis for cyclooxygenase 2 in the differential diagnosis of osteoblastoma and osteosarcoma

Osteoblastoma of the Larynx: A Case Report

We describe a unique case of an osteoblastoma in the cricoid cartilage of a 50-year-old man who presented with hoarseness and progressive dyspnea. Panendoscopic examination revealed a reddish tumor at the left side of the cricoid cartilage. Computed tomography (CT) imaging showed a sclerotic lesion involving the cricoid cartilage, protruding in the airway lumen. The tumor was removed via an external procedure. Histology confirmed the diagnosis of osteoblastoma.

Osteoblastoma of the metacarpal: A case report

Osteoblastoma is a rare tumor, but the small bones of the hands and feet are the second most common location. Despite this, the diagnosis of osteoblastoma is rarely considered in the differential diagnosis of bone tumors of the hand. This is a case similar to Jaffe and Mayer's original report.