Diagnosis Of Giant Cell Granuloma Research Articles

Abordagem farmacológica em lesão central de células gigantes: Relato de caso

Objetivo: Relatar o processo diagnóstico da Lesão Central de Células Gigantes e as opções de terapias farmacológicas disponíveis como alternativa para o tratamento cirúrgico enquanto conduta de primeira escolha. Estudo de Caso: Paciente do sexo feminino, 24 anos, apresentava aumento de volume assintomático em região de corpo mandibular direito. A conduta inicial foi a realização da biópsia incisional e após a análise histológica foi necessário solicitar exames laboratoriais para distúrbios paratireoides a f im de descartar a possibilidade do Tumor Marrom. Os resultados se apresentaram dentro dos padrões de normalidade e uma vez elucidado o diagnóstico de Lesão Central de Células Gigantes foi iniciado o tratamento com injeções intralesionais de triancinolona. Com 09 meses do início do tratamento, a paciente encontra-se com remissão significativa da lesão e ao exame tomográfico observa-se neoformação óssea satisfatória. Considerações Finais: A Lesão Central de Células Gigantes demanda de um extenso processo diagnóstico e dispõe de tratamentos cirúrgicos e/ou farmacológicos, cabe ao profissional responsável pelo caso ponderar a melhor abordagem para cada paciente.

A Rare Presentation of Central Giant Cell Granuloma of the Maxillary Sinus

Central giant cell granuloma (CGCG), also known as giant cell reparative granuloma, is a non-cancerous proliferative lesion of unknown etiology. It is a localized osteolytic lesion with the diverse biological behavior of aggression which most commonly affects the mandible and other jaw bones. It is a rare condition and its characteristic clinical or radiological features are still not well defined. It resembles to some neoplasms and can easily be misdiagnosed with Antro- Choanal Polyp, Angiofibroma, Squamous Cell Carcinoma and inverted Cell papilloma.We are reporting a case of rare presentation of CGCG arising from the maxillary sinus. This is a case report of a 15 year old boy who presented with the episodes of recurrent epistaxis and nasal obstruction. Diagnosis of giant cell granuloma was made on the basis of age presentation, rare location, and histological findings of excised specimen, which revealed central giant cell granuloma. This case helps to demonstrate the wide variation in the clinical and radiological features of CGCG and highlights the significance of histological features of this lesion.

An Unusual Case of Maxillary Central Giant Cell Granuloma

Central giant cell granuloma, formerly known as giant cell reparative granuloma, is considered as a reactive lesion to an unknown stimulus or a neoplastic lesion. The lesion mainly affects young adults and commonly involves mandible more than maxilla. When present in the maxilla, it is usually seen anterior to cuspids, but in this case, it was the posterior maxilla which was involved making it an unusual site for its occurrence. This case report describes a 20-year-old female patient presenting with a chief complaint of swelling of the left side of the face for 1-year. Depending on the clinical features and radiographic findings, a diagnosis of giant cell granuloma was made, which was surgically excised.