This study aimed to identify the sociodemographic, clinical, and nutritional profile, as well as to determine the incidence and lethality rate for COVID-19 in elderly residents in Long-Term Care Institutions for the Elderly in the municipality of Maceió – Alagoas, in the period 2020 and 2021. In the first year of the pandemic in Maceió, the reported incidence of COVID-19 was 31/100 residents in LTCFs, while the lethality rate was 6.56%, with elderly males representing the largest number of deaths (62.5%), the variables that presented as risk factors were sex, age, previous diagnosis of DM and low weight (p < 0.050) and the variable education (p = 0.081). The data from this research reinforce results presented by other researchers where the previous diagnosis of diabetes is associated with the outcome death and male gender, age, low education and BMI are associated with the occurrence of the disease.