Development Of Ventricular Assist Devices Research Articles

The Development of Ventricular Assist Devices over the Past 30 Years: A Bibliometric Analysis

Background: A large gap exists between the needs of patients with end-stage heart failure and the number of gold-standard heart transplants. Over the past 30 years, a revolutionary treatment strategy using ventricular assist devices (VADs) has rapidly developed and become widely used in clinical practice. However, few analyses have assessed the application and publication trends in the VAD field. Method: We used the Web of Science core collection to identify VAD research published between 1992 and 2022. We performed analysis and data visualization with CiteSpace, Scimago Graphica, and VOSviewer. Results: We identified 13,274 articles published in 1129 journals, describing work from 6351 institutions in 86 countries. Among them, the United States contributed the most to VAD research, and almost all the top ten authors and institutions contributing to VAD research were from the United States. Conclusions: In the past 5 years, VAD research has focused on right heart failure, outcomes, effects and risk factors, societies of surgeons, and clinical guidelines. Because of the large number of patients with heart failure, we expect VAD development to peak in the next decade.

Ventricular Assist Device Development: Women and Children Should No Longer Be Last!

Ventricular Assist Device Development: Women and Children Should No Longer Be Last!

Application Of LDV Profile Sensor Technology For Velocity Determination In Small Axial Gaps

In development of Ventricular Assist Devices (VADs), Computational Fluid Dynamics (CFD) have arise as a powerful tool to gain insights on flow topologies within rotary blood pumps. Information regarding flow patterns and shear-stress distributions is of enormous importance, since flow induced blood damage as well as platelet activation is at-tributed to shear rates. Although methods for verification of numerical results are available, a lack of experimental validation is recognizable. To enable an experimental validation (i) hydraulic properties as well as flow patterns need to be preserved and (ii) a non-intrusive optical measurement technique needs to be capable of resolving flow topolo-gies appearing in rotary blood pumps. In this paper references to address (i) are provided and the focus is placed on (ii) by presenting a methodology to resolve flow topologies by usage of LDV Profile Sensor technology. This paper serves as a feasibility study and represents a preliminary stage towards actual optical measurements with rotary blood pumps. Therefore, a test bench with facilitated optical accessibility compared to Ventricular Assist Devices as well as operating conditions are introduced. Increased attention is dedicated to evaluation of measurement data by means of choosing a suitable procedure. Therefore, commonly used 2D-histograms for LDV raw data evaluation are compared to the method of Gaussian Kernel Density Estimation (Gaussian KDE). Subsequently, pre-processed raw data is further evaluated with a specially tailored Velocity Profile Validation Algorithm and determined circumferen-tial velocity profiles are discussed. In summary, herein presented feasibility study is deemed successful and LDV Pro-file Sensor technology is capable of resolving flow topologies within small gaps as they appear in Ventricular Assist Devices. Thus, LDV Profile Sensor technology may improve development of rotary blood pumps.

人工心臓の実用化 : 人工心臓をつけて家族のもとへ帰ろう(機械の進歩 激動の四半世紀)

人工心臓の実用化 : 人工心臓をつけて家族のもとへ帰ろう(<メカライフ特集>機械の進歩 激動の四半世紀)

Destination Therapy: Does Progress Depend on Left Ventricular Assist Device Development?

The role of therapy using mechanical circulatory support devices has evolved rapidly over the last two decades. New developments in the field achieved smaller adverse events, but, currently, only minor improvements in survival were observed in published observational data. The authors discuss the development of mechanical circulatory support devices as a "destination therapy" option for patients who have end-stage heart failure and are ineligible for heart transplantation as it relates to left ventricular assist device development.

Development of Ventricular Assist Device Driven by Autologous Latissimus Dorsi Muscle

Development of Ventricular Assist Device Driven by Autologous Latissimus Dorsi Muscle

Development and clinical assay of the BCM ventricular assist device.

The development of a ventricular assist device is depicted. The seven subprograms that make up the project are described briefly. Results obtained during the clinical assay showed that the new design of the input cannula working as a false auricle provides better efficiency, as well as a certain level of autoregulation for the device.