Development Of Medical Materials Research Articles

Mechanical Properties of Biocomposite with Various Composition of CaCO3 and Starch

Calcium carbonate has the potential to be used in the development of medical materials, including biomaterials. Biocomposite is composed of CaCO3 as matrix material and bioplastic from the combination of corn starch and cassava starch as reinforcement. This study aims to determine mechanical properties such as tensile strength and bending/flexural strength with varying compositions of CaCO3 and bioplastic. Characterization of the biocomposite uses Scanning Electron Microscope to observe the microstructure and composition elements of their structure. This study used 4 variations in the ratio of CaCO3 suspension: (Corn Starch + Cassava Starch). Each sample was characterized using specimen code A for composition 30:70 (w/w) percent and specimen B for composition 40:60 (w/w) percent, specimen C for composition 50:50 (w/w) percent, and specimen D for composition 60:40 (w/w) percent. Based on the results of shrinkage measurements on flexural strength specimens, specimen B has the lowest percentage value of 15±0.01 percent. The lowest tensile strength specimen is found in specimens C and D at 12±0.01 percent. The tensile test results also showed that specimen D had a higher ultimate strength value than the other specimens, which was 0.06±0.03 MPa. Microstructure characterization was carried out using scanning electron microscopy with energy-dispersive X-ray spectroscopy, which revealed the presence of Oxygen at approximately 48.39 percent mass, Carbon at approximately 30.27 percent mass, Nitrogen at approximately 11.77 percent mass, Calcium at approximately 9.57 percent mass, with Calcium being detected in the form of Calcium Carbonate (CaCO3).

Development of Medical Materials and Infection

Surgery has the possibility to cause infections. Surgical site infection(SSI)is a common complication of various surgical procedures. On the other hand, allogeneic tissue-derived material-induced infections, such as transfusion-related hepatitis and Creutzfeldt-Jakob disease, are rare but occur. The risk of surgery-related infections needs to be reduced because such infections not only affect morbidity and mortality but also lead to increased medical costs and longer hospitalization. Recently, various allogeneic and synthetic medical materials have been developed, and many types of materials have been used in daily neurosurgical procedures. Some synthetic materials have been advertised to have an SSI-preventive effect. Technology has also been developed to minimize the infectivity of allogeneic materials. In this paper, we introduce some information focused on the infectivity of fibrin glue and DuraGen® and the SSI-preventive effect of Surgicel® and antimicrobial sutures.

Synthesis, Properties, and Biological Activity of Poly(1-vinyl-1,2,4-triazole) and Silver Nanocomposites Based on It

The review summarizes the data on the synthesis, physicochemical properties, and biological activity of poly(1-vinyl-1,2,4-triazole) and its nanocomposites with silver nanoparticles. The results of studying the antibacterial and antitumor activity of the polymers and nanocomposites and their immunomodulatory ability, toxicity, and interaction with body cells, as well as the prospects for their use in the development of medical materials, are presented.

Progress in research of peritoneal dialysis complicated with peritonitis

In recent years, reports on the effects of nursing intervention on the incidence of peritoneal dialysis complicated with peritonitis have been increasing. With the advancement of medical technology and the development of medical materials, complications of peritoneal dialysis show a decreasing trend. Many experts and scholars have been continually exploring the causa morbid of peritoneal dialysis and excogitating measures that should be taken. In this paper a comprehensive review is done.