The rapid development of economic and urbanization systems exerts a negative impact on environmental system. To achieve the sustainable development of a country, it is important to obtain an in-depth understanding of the interaction among economic, urbanization and environmental systems. A coupling coordination model of the three systems is constructed in this research to investigate the interactions among the three systems in China. This study determines the contribution rate of each indicator to the three systems during the studied period, then evaluates the development levels of the three systems and finally explores coupling coordination levels among them. The results show that economic scale, spatial urbanization and environmental governance are the prominent indicator in the economic, urbanization and environmental systems, respectively. The findings suggest that the policy makers need to consider these indicators for the development of the three systems. Furthermore, the development level of economic, urbanization and environmental systems in China generally shows an upward trend, while the environmental system development has been lagging behind the development level of economic and urbanization systems. The spatial difference exists chronically, but such differences are gradually decreasing as time evolves. Among these systems, the reduction of difference in urbanization system is most obvious. Although the coupling coordination level of the three systems presents an upward trend, unbalanced development of these systems in regional level still exists. The insightful implications are discussed for coordinated development.