Objective: To study the applicability, the high frequency used content, the feasibility, and issues needed to be solved of the standard of GBZ 1-2010, aiming to provide technical evidence for the revision of GBZ1. Methods: In the study, the data were collected by referring to the literature database and the questionnaire from June 2013 to June 2015. There were 2 surveys carried out in the study, with methods including questionnaire survey and specific interview. The investigation methods include the paper version of the questionnaire by mail, the electronic version of the questionnaire by e-mail, and the online survey. And 111 questionnaires were collected. Results: In total, the applicability survey (the first survey) received 156 suggestions covering 76 items from 23 facilities, and 13 key technical issues were summarized to be solved as priorities. In the application survey (the second survey) , the leading three jobs using GBZ 1-2010 were the occupational hazards evaluation for constructive project (82.0%) , lecturing/training (65.8%) , occupational hazards monitoring (64.9%) , respectively. The high frequency used contents of GBZ 1-2010 were the sixth part "the basic hygienic requirements for workplace" (90.1%) , the fifth part "site selection, overall layout and workshop design" (87.4%) , the seventh part "the basic hygienic requirements for welfare room" (85.6%) , respectively. In the results of feasibility, scores of the fourth part "the general rules" , the fifth part "site selection, overall layout and workshop design" , the sixth part "the basic hygienic requirements for workplace" , the seventh part "the basic hygienic requirements for welfare room" , the eighth "emergency rescue" , annex A "the correct use instructions" , annex B "buffer zone standards for industrial enterprises" were 2.6, 3.1, 3.5, 3.8, 3.2, 3.3, 2.6, respectively. Among 111 questionnaires, the parts needed to be modified as priories were the fifth part "site selection, overall layout and workshop design" (51.4%) , and the sixth part "the basic hygienic requirements for workplace" (51.4%) . In results of the key technical issues needed to be modified of GBZ 1-2010, the contents needed to be added as priories were the occupational prevention and control requirements of biological factors (51.4%) , technical parameters of dust in workplace (48.7%) , technical parameters of hazardous agents in workplace (46.9%) , the quality and quantity requirements of fresh air (46.0%) , the setting conditions of the emergency rescue station (46.0%) , the hygienic design requirements of joint workshops and the evidence (45.1%) , and requirements for medical emergency rescue personnel equipped and qualified (45.1%) . Conclusion: GBZ 1-2010 is feasible and practical, mainly used by occupational health technical service organizations in the occupational hazards evaluation for constructive project, lecturing/training, occupational hazards monitoring, et al. GBZ 1 plays a directive role in government decision-making, control of constructive projects from the beginning, training and capacity building of occupational health professionals, and the prevention and treatment of occupational diseases in enterprises, needing to strengthen the implementation of GBZ 1. And on the basis of the above key technical issues to be revised, international cooperation and exchanges should be strengthened, so that it is adapted to the development of the modern enterprise system.