Abstract To successfully implement comprehensive, multidisciplinary and interdisciplinary approaches, collaborative, cross-sectoral policy and strategies are essential. This is critical not only for addressing shared challenges but also for developing effective intervention strategies. One of the main hurdles in any collective action initiative is the ability to galvanize diverse stakeholders, each with their unique set of interests and capacity. EUVABECO is dedicated to conducting pilots, and developing implementation plans that are not only effective but also adaptable and sustainable across various healthcare settings in Europe. The healthcare environments across the pilot countries exhibit considerable variability, including differences in epidemiological trends, immunization information systems, vaccine nomenclature, and the dynamics of collaboration with National Immunization Technical Advisory Groups (NITAGs). Throughout implementation, the cooperation between these diverse stakeholders and NITAGs will be crucial, notably to share local vaccination policies for integration into the Clinical Decision Support (CDS) system. EUVABECO’s goal is to craft implementation plans that are flexible enough to be tailored to local needs, ensuring that interventions are both practical and effective in each unique context. This presentation will explore the vital role that stakeholders and NITAGs play in this process, highlighting the importance of their involvement for the success of EUVABECO’s initiatives.