Deterioration Of Human Health Research Articles

A network frame offers a promising transdisciplinary tool for understanding complex health and health care system problems like suicide

As health and health care systems continue to face massive challenges from local to global well-being, understanding the processes that lead to improvement or deterioration in human health has embraced a broad range of forces from genes to national cultures. Despite the many efforts to deploy a common framework that captures diverse drivers at scale, the common missing element is the absence of a flexible mechanism that can guide research within and across levels. This hinders both the cumulation of knowledge and the development of a scientific foundation for multiplex interventions. However, studies across disciplines using a wide variety of methods and measures have converged on "connectedness" as crucial to understanding how factors operate in the health space. More formally, a focus on the critical role of the network structure and content of key elements and how they interact, rather than just on the elements themselves, offers both a generalized theory of active factors within levels and the potential to theorize interactions across levels. One critical contemporary health crisis, suicide, is deployed to illustrate the Network Embedded Symbiome Framework. The wide range of health and health care research where networks have been implicated supports its potential but also cautions against inevitable limits that will require creative theorizing and data harmonization to move forward.

Exploring the Impact of Lead on Health and Strategies to Prevent the Adverse Consequences

Lead is one of the ten chemicals of major public health concern, and has been linked to environmental degradation and significant deterioration of human health. Multiple age-group-specific harmful effects in children, pregnant women, and adults have been reported secondary to lead exposure. Even though lead-associated adverse effects have been recognized in different parts of the world, the key barrier is the least priority assigned to it by public health officials worldwide. To conclude, owing to both short- and long-term effects of lead in different age groups, it is high time that global policymakers should prioritize lead poisoning and take appropriate measures to effectively deal with the public health menace of lead.

Synthetic Degradable Polyvinyl Alcohol Polymer and Its Blends with Starch and Cellulose-A Comprehensive Overview.

Approximately 50% of global plastic wastes are produced from plastic packaging, a substantial amount of which is disposed of within a few minutes of its use. Although many plastic types are designed for single use, they are not always disposable. It is now widely acknowledged that the production and disposal of plastics have led to a plethora of negative consequences, including the contamination of both groundwater and soil resources and the deterioration of human health. The undeniable impact of excessive plastic manufacturing and waste generation on the global plastic pollution crisis has been well documented. Therefore, degradable polymers are a crucial solution to the problem of the non-degradation of plastic wastes. The disadvantage of degradable polymers is their high cost, so blending them with natural polymers will reduce the cost of final products and maximize their degradation rate, making degradable polymers competitive with industrial polymers that are currently in use daily. In this work, we will delineate various degradable polymers, including polycaprolactone, starch, and cellulose. Furthermore, we will elucidate several aspects of polyvinyl alcohol (PVA) and its blends with natural polymers to show the effects of adding natural polymers on PVA properties. This paper will study cost-effective and ecologically acceptable polymers by combining inexpensive natural polymers with readily accessible biodegradable polymers such as polyvinyl alcohol (PVA).

Highly conserved bifidobacteria in the human gut: Bifidobacterium longum subsp. longum as a potential modulator of elderly innate immunity.

Aging is a physiological and immunological process involving the deterioration of human health, characterised by the progressive alteration of organs and their functions. The speed and extent of such decline are dependent on lifestyle, environment, and genetic factors. Moreover, with advancing age, humans become progressively more fragile and prone to acute and chronic diseases. Although the intestinal microbiota is predisposed to perturbations that accompany aging and frailty, it is generally accepted that the gut microbiota engages in multiple interactions that affect host health throughout the host life span. In the current study, an exhaustive in silico investigation of gut-associated bifidobacteria in healthy individuals from birth to old age revealed that Bifidobacterium longum subsp. longum is the most prevalent member, especially during infancy and in centenarians. Moreover, B. longum subsp. longum genome reconstruction and strain tracing among human gut microbiomes allowed the identification of prototypes of this taxon in the human gut microbiota of healthy elderly individuals. Such analyses guided culturomics attempts to isolate B. longum subsp. longum strains that matched the genomic content of B. longum subsp. longum prototypes from healthy elderly individuals. The molecular effects of selected B. longum subsp. longum strains on the human host were further investigated using in vitro microbe-host interactions, revealing differences in the host immune system transcriptome, with a reduction in gene expression of inflammation-related cytokines. These intriguing findings support the potential anti-aging effects of elderly associated prototypes of B. longum subsp. longum.

Fabrication of bare and cobalt-doped ZnFe2O4 thin film as NH3 gas sensor with enhanced response through UV-light illumination

This work reports on the deposition of bare and cobalt-doped ZnFe2O4 thin films by chemical spray pyrolysis technique to study ammonia (NH3) gas sensing properties. Colorless and strongly smelling, ammonia (NH3) is readily soluble in water and yields ammonium (NH) ions. These gases mix in the air atmosphere cause climate change, and severely affect human health. Therefore, the detection of NH3 below the exposure limit can avoid the deterioration of human health and environment. Co-doping had a significant effect on surface roughness, surface morphology, crystallite size, and sensitivity at room temperature. Co0.5Zn0.5Fe2O4 film (ZFCO5) exhibited an outstanding response (S = 19) towards 10 ppm NH3 gas at room temperature. Compared to the bare film, the ZFCO5 sensor has an eleven-fold higher gas-detection response value for 10 ppm NH3. This is ascribed to the blended effects of small crystallite size, high surface roughness, oxygen vacancies, and angular shape morphology linked into tiny rods in the ZFCO5 film. The ZFCO5 sensor showed a significant speedup in response/recovery times (102 s/34 s) and good response (S = 25) to NH3 under the UV-light (365 nm) illumination at room temperature. The built-in ZFCO5 gas sensor shows promise for real-time NH3 below threshold level monitoring.

Fight Against Hidden Hunger: Boosting Zinc in Potato through Biofortification in Calcareous Soil of Bihar, India

Micronutrients are often overlooked during fertilizer application, which reduces the content of micronutrients in the soil and crops. The concentration of micronutrients in our meals is decreasing considerably, creating several abnormalities in human body and deterioration of human health, although we consume adequate amount of food, we do not get enough nutrients, which is labeled as hidden hunger. To increase the micronutrient concentration in potato crop, particularly, Zinc, this research was conducted in the Rabi season of 2022 at TCA-Dholi, Dr. RPCAU, Pusa, Bihar. Kufri Khyati, a popular variety in Northern Bihar was given ten treatments and replicated four times, in Randomized Block Design (RBD), experimental design. The concentration of Zn in leaves (95.45 ppm), in tubers (31.50 ppm), SPAD meter reading at 45 DAP, 60 DAP and 75 DAP (49.29, 42.04, 37.11, respectively), yield of tubers (25.17 t ha-1), and B:C ratio (2.97) were maximum in treatment T10 (Zn-EDTA @ 4g litre-1 at 25 and 50 DAP).

Mortality and Survival Analysis in COVID-19 Patients: Hematological and Biochemical Study

Severe acute respiratory syndrome (SARS-CoV-2) that causes novel coronavirus pneumonia (COVID-19) interacts with the receptor (angiotensin-converting enzyme) on the lung epithelial cells and leads to rapid deterioration of human health if no care is provided, hence risk identification of the case severity is important. The objective of the present study is to analyze the relationship between blood parameters and the severity, survival, and mortality of COVID-19 patients based on the hematological and biochemical abnormalities associated with Iraqi COVID-19 patients. A prospective multicenter observational study has been done on a total of 103 patients admitted to different hospitals between November 1, 2021, and April 1, 2022. Among these 30 (29.1%) patients died, 81% died within two weeks of admission to the hospital, and 73 patients (71.9%) survived. An independent sample t-test revealed a significant difference in the tests including AST, ALT, D-dimer, urea, creatinine, and chloride ion between the dead and survived patients, while there was a non-significant difference when these parameters were compared (age, BMI, CPR, PT, INR, APTT, WBC, LYM, GRA, HGB, RBC, ESR, Creatinine, Na and K ions). Crosstab’s study showed that most death (80%) were at ages >60 years, 53.3% of the deaths were having normal BMI and only 10% were obese. Three models for logistic regression were performed to test if the available data set is more effective than the null hypothesis, all three tests yield a similar conclusion that the available data can be used to check the risk factors in COVID-19 patients.

The effect of meteorological parameters on air particulate matter

The conditions of the weather have an effect on both the amount of emissions and the quality of the air. A change in meteorological conditions has a substantial effect on particulate matter (PM) levels. In this study, we will first use statistics and wavelet calculations to look at the links between particulate matter (PM10 and PM2.5) and relative humidity (RH). RH influences the natural deposition of PM concentrations. Then, we’ll examine how wind direction (WD) and wind speed (WS) affect PM. The results show that both PM10 and PM2.5 are high in February and that July and August have the lowest levels. In contrast, RH is low in February and maximum in October. Whenever the RH increases, the PM concentration decreases, and vice versa. The correlation coefficients between PM10 and RH are 0.3433 during the winter, 0.7181 during the summer, and 0.0052 during the rainy season. This illustrates the significant seasonal correlation between PM and RH. The results from wavelet coherence analysis indicate that PM and RH have close negative correlations. Significantly high wavelet power in the 8–30 day waveband exists in winter each year in the observed time horizon. There is also another common power found throughout the spectrum. PM and RH in these wavebands are out of phase with one another, with RH slightly leading PM. Moreover, the WS and WD also have an effect on PM concentration. If the wind speed is high and exceeds a specific threshold, the wind will take PM away, causing the PM concentration to decrease. In February 2023, the NE and NNE winds carried the most PM into the Bangkok region, followed with less concentration, by the WSW, SW, and W winds. Since PM is one of the primary air contaminants that has been linked to a deterioration in human health, it is extremely important to have a solid understanding of how PM concentrations change over time.

The Ideal Diet for Humans to Sustainably Feed the Growing Population – Review, Meta-Analyses, and Policies for Change

Introduction: As of now, no study has combined research from different sciences to determine the most suitable diet for humans. This issue is urgent due to the predicted population growth, the effect of this on the environment, and the deterioration of human health and associated costs. Methods: A literature review determined whether an optimal diet for humans exists and what such a diet is, followed by six meta-analyses. The standard criteria for conducting meta-analyses of observational studies were followed. A review of literature reporting Hazard Ratios with a 95% confidence interval for red meat intake, dairy intake, plant-based diet, fiber intake, and serum IGF-1 levels were extracted to calculate effect sizes. Results: Results calculated using NCSS software show that high meat consumption increases mortality probability by 18% on average and increases diabetes risk by 50%. Plant-based and high-fiber diets decrease mortality by 15% and 20% respectively (p < .001). Plant-based diets decreased diabetes risk by 27%, and dairy consumption (measured by increased IGF-1 levels) increased cancer probability by 48% (p < 0.01). A vegetarian or Mediterranean diet was not found to decrease the probability of heart disease. A vegetarian diet can be healthy or not, depending on the foods consumed. A Mediterranean diet with high quantities of meat and dairy products will not produce the health effects desired. The main limitations of the study were that observational studies were heterogeneous and limited by potential confounders. Discussion: The literature and meta-analyses point to an optimal diet for humans that has followed our species from the beginnings of humankind. The optimal diet is a whole food, high fiber, low-fat, 90+% plant-based diet. This diet allowed humans to become the most developed species on Earth. To ensure people’s nutritional needs are met healthily and sustainably, governmental dietary interventions are necessary.

Rеsеаrch on Еcologіcal and Еconomic Dеvеlopmеnt and it is Impact on Еcology

Abstract. Introduction. The beginning of the 21st century for the world population became an obvious approach of a global catastrophe associated with large pollution of the natural environment, the destruction of the ozone layer of the biosphere, the increase in climate change, and the dangerous degeneration of flora and fauna. Scientists predict that if society does not change the directions of socio-economic development, technological methods of mastering nature, then the beginning of irreversible destruction of the biosphere is predicted in the near future. Purpose. Ensuring the economic growth of the country at present is accompanied by the growth of environmental pollution and degradation, depletion of natural resources, disruption of the balance of the biosphere, climate change, which leads to the deterioration of human health and limits the possibilities of further development This means that the level of well-being of the population is tight related to ensuring the quality of the environment. The development of industrial society gave rise to new needs, and the need to satisfy them required a new increase in production, the consequences of such development became a heavy yoke for the environment. Along with the growth of labor productivity and the improvement of the efficiency of the economic activity of enterprises, today the question is their willingness to apply advanced technologies capable of reducing the negative impact on the environment and more rationally using natural resources, increasing the level of waste processing and mastering zero-waste technologies. Conclusions. This testifies to the relevance of the conducted research, the purpose of which was analytical work on the interrelationship of environmental and economic factors of the development of society with the position of the unity of these processes. The solution to the given task was performed on the basis of the interrelationship of resource and environmental factors. It is stated that one of the components of the modern development of the economy is the substantiation of the economic and scientific relationship to environmental safety. A possible association is economic activity with indicators of the economic state and the nature of the impact on it.

Scale Effect of Surface Asperities on Stick–Slip Behavior of Zinc-Coated Steel

Stick-slip behavior between friction pairs causes severe vibration problems such as abrasion and noise pollution, leading to material loss and deterioration in human health. This phenomenon is extremely complex because the surfaces of friction pairs have various asperities with different sizes. Therefore, it is of importance to understand the scale effect of asperities on the stick-slip behavior. Here, we selected four kinds of zinc-coated steels with multiscale surface asperities as a presentative example to reveal what types of asperities play the key role in affecting the stick-slip behavior. It is discovered that the stick-slip behavior is dominated by the density of small-scale asperities rather than large-scale asperities. High-density small-scale asperity increases the potential energy between asperities of the friction pairs, which leads to stick-slip behavior. It is suggested that decreasing the density of small-scale asperity on the surface significantly suppresses the stick-slip behavior. The present study reveals the scale effect of surface asperities on the stick-slip behavior and thus could offer a pathway to tailoring the surface topography of a wide range of materials for suppressing the stick-slip behavior.

Hydrothermal liquefaction could be a sustainable approach for valorization of wastewater grown algal biomass into cleaner fuel

Studies highlighting the actual roadblocks in sustainability of algal fuels require systemic analysis using real-time experimental inventories. In view of this, the authors performed Life Cycle Assessments (LCAs) for 3 previously developed algal biofilms-based conversion systems; 1) wastewater grown algae (WWA) processed via anaerobic digestion (AD), 2) WWA processed via hydrothermal liquefaction (HTL) and 3) synthetic media grown algae (SMA) processed via HTL. Their environmental impacts were compared for resources depletion, ecosystem damage, human health deterioration and climate change. Results showed that HTL of WWA had 41.1 % lesser impact compared to AD of the same biomass, because of the huge energy input, production of CO2 and huge volume of algal digestate. Due to the short reaction time in HTL (20 min), energy input and resources usage was minimal. Further, the HTL of WWA showed 98% lesser impact than HTL of SMA. HTL of SMA had larger impact on the human health (3.95Pt), compared to HTL of WWA (0.25Pt). The latter also showed positive impact on the eutrophication reduction due to the treatment of wastewater during algal cultivation. The global warming potential for biocrude production from WWA was 10 times lower than biomethane production from the same biomass and 21 times lower than the biocrude production from SMA. The results of the comparative LCAs proved that HTL of WWA is a sustainable route for valorizing the biomass. Based on the LCA outcomes, shortcomings of the respective algal technologies were identified, and improvement strategies were suggested.

인도 쓰레기매립지의 환경문제에 관한 법적 해결 방안에 대한 연구

This paper considers the environmental disputes caused by the landfills located in Delhi, India and reviews the Indian Waste-to-Energy policy to resolve the environmental conflicts. India has sound waste management rules and regulations but they are not implemented effectively. Even though the Indian government has applied current Indian environmental policies, such as municipal solid waste rule, it could not properly resolve these disputes based on a lack of administrative will-power. India being the world’s second most populous country generates an enormous amount of garbage. While the waste generated is not managed effectively, it might lead to deterioration of human health and the environment. The waste is usually dumped in Landfills. However, these landfills are poorly managed, and the waste keeps overflowing. Numerous Landfills have led to fire around the locality, and they are a source of nuisance to the neighbourhood. One of the possible solutions could be using waste to energy plants. Waste-to-energy plants use state of the art technology to incinerate the garbage to produce energy. Waste could be used to produce clean energy and could curb pollution. However, the application of thermal technology for waste-to-energy in India is not well controlled because the cost of using crude oil is much cheaper than the expense of applying waste-to-energy technology in India. One of the possible remedies could be under statutory nuisance which would compel the regulatory authorities to protect the human health and the environment.

Facile Electrodeposition-Based Chemosensors Using PANI and C-Hybrid Nanomaterials for the Selective Detection of Ammonia and Nitrogen Dioxide at Room Temperature

Sensor systems for monitoring indoor air quality are vital for the precise quantification of the mechanisms which lead to the deterioration of human health, with a typical person spending an average of 20 h a day in an enclosed space. Thus, a series of layered chemoresistive sensors, obtained by the facile electrodeposition of carbon nanomaterial-enhanced PANI composites, have been tested for the selective detection of two core indoor pollutants: ammonia and nitrogen dioxide. The sensors were tested with respect to sensitivity and selectivity to the target gasses, with performance being assessed based on response linearity and repeatability at room temperature. Of the tested sensors, two have been identified as having an adequate performance on ammonia, with sensitivities of up to 96.99% and resolutions of up to 0.85 ppm being observed, while on nitrogen dioxide, despite the successful sensor having a lower sensitivity, 10.71%, it has shown high resolution, 1.25 ppm, and linearity over a large concentration domain. These high performances highlight the viability of multi-layers chemosensors based on the electrodeposition of nanomaterial-enhanced conductive polymers for the detection of pollutant gasses, with finetuning of the detection layer allowing the accurate monitoring of a wide range of gasses.

Xenobiotic-Metabolizing Enzymes in Trematodes.

Trematode infections occur worldwide causing considerable deterioration of human health and placing a substantial financial burden on the livestock industry. The hundreds of millions of people afflicted with trematode infections rely entirely on only two drugs (praziquantel and triclabendazole) for treatment. An understanding of anthelmintic biotransformation pathways in parasites should clarify factors that can modulate therapeutic potency of anthelmintics currently in use and may lead to the discovery of synergistic compounds for combination treatments. Despite the pronounced epidemiological significance of trematodes, there is still no adequate understanding of the functionality of their metabolic systems, including xenobiotic-metabolizing enzymes. The review is focused on the structure and functional significance of the xenobiotic-metabolizing system in trematodes. Knowledge in this field can solve practical problems related to the search for new targets for antiparasitic therapy based on a focused action on certain elements of the parasite's metabolic system. Knowledge of the functionality of this system is required to understand the adaptation of the biochemical processes of parasites residing in the host and mechanisms of drug resistance development, as well as to select a promising molecular target for the discovery and development of new anthelmintic drugs.

Oxi-inflammatory stress and vascular cell adhesion molecule-1 in post-COVID active rheumatoid arthritis patients

Background: Coronavirus disease-19 (COVID-19) has sparked the deterioration of human health at an unprecedented scale globally and affected the patient’s musculoskeletal health also. It is conceivable that active rheumatoid arthritis (ARA) patients recovered from COVID-19 after second wave are at enhanced risk of cardiovascular complications. Aim and Objectives: In this context, the present study was intended to estimate the soluble vascular cell adhesion molecule-1 (sVCAM-1), serum paraoxonase (PON), and markers of oxi-inflammatory stress in ARA patients diagnosed reverse transcriptase-polymerase chain reaction negative after second wave of COVID-19 and to determine their role in predicting cardiovascular disease (CVD) risk. Materials and Methods: Sixty ARA patients (30–45 years) of Delhi-NCR region were recruited and categorized into two groups (n=30 in each group; on the basis of their history of COVID infection). Using standard methods, study group parameters were estimated in ARA patients and statistically compared it with that of 30 healthy controls by using student’s t-test. Results: Serum sVCAM-1, malondialdehyde (MDA), and C-reactive protein (CRP) levels were significantly high (P<0.001) in Group II and Group III subjects as compared to healthy controls. Conversely, serum PON activity was found to be significantly low (P<0.001) in Group III as compared healthy controls. However, PON activity was altered insignificantly (P<0.1) with respect to Group II subjects. sVCAM-1 levels were positively correlated with MDA, CRP, and atherogenic index; and negatively correlated with PON activity (P<0.001) in post-COVID ARA patients. Conclusion: Thus, enhanced sVCAM-1 and reduced PON activity along with enhanced oxi-inflammatory stress status are more efficient molecular signatures of CVD risk among post-COVID ARA patients. Therefore, the present study emphasizes the dire need of special attention to provide cardiovascular rehabilitation strategy among post-COVID ARA patients along with reduction of oxi-inflammatory stress to reduce the CVD mortality in ARA population.

Energy-efficient environmentally friendly electric device for the destruction of weeds by heating them

Weeds damage cultivated agricultural plants. There are many ways to control weeds. These include biological, chemical, mechanical and electrical methods. With an increase in sown areas, the types of weeds increase. On the one hand, weeds perform some useful functions, such as transporting moisture and trace elements from the soil, increasing the diversity of flora. However, with a very large number of weeds, the yield can be reduced by up to 50%. The use of pesticides to kill weeds leads to environmental pollution and deterioration of human health. Certain types of chemicals cause cancer disease. In recent years, smart technologies have appeared for the local application of pesticides in weed control. At the same time, there is a decrease in pesticides up to 90%. Intelligent technologies allow effective control of weeds. Burning weeds directly in the fields leads to a decrease in soil humus and, subsequently, to a decrease in land productivity. We have developed a method and a device for the destruction of collected weeds directly on the field using energy-efficient electric contact heating. This technology and electrical circuit can be connected to both centralized power supply and autonomous power (diesel or solar power plants). In order to save energy resources, an electronic model for the use of a solar beam concentrator is also proposed.

Solid-state synthesis of CdFe2O4 binary catalyst for potential application in renewable hydrogen fuel generation

Clean energy is highly needed at this time when the energy requirements are rapidly increasing. The observed increasing energy requirement are largely due to continued industrialization and global population explosion. The current means of energy source is not sustainable because of several reasons, most importantly, environmental pollution and human health deterioration due to burning of fossil fuels. Therefore, this study develops a new catalyst for hydrogen and oxygen evolution by water splitting as a potential energy vector. The binary metal oxide catalyst CdFe2O4 was synthesized by the solventless solid-mechanical alloying method. The as-prepared catalyst was well characterized by several methods including field emission scanning electron microscopy (FESEM), X-ray diffraction spectroscopy (XRD), X-ray photoelectron spectroscopy (XPS), Fourier Transform infrared red spectroscopy (FTIR), energy dispersive X-ray spectroscopy (XEDS). The as-prepared catalyst, CdFe2O4 was successfully applied for water electrolysis at a moderate overpotential (470 mV). Specifically, the onset potential for the oxygen and hydrogen evolution reactions (OER and HER) were 1.6 V/RHE and 0.2 V/RHE respectively (vs. the reversible hydrogen electrode). The electrode potential required to reach 10 mA/cm-2 for OER (in alkaline medium) and HER (in acidic medium) was 1.70 V/RHE (corresponding to overpotential η = 0.47 and − 0.30 V/RHE (η = − 0.30 V) respectively. Similarly, the developed OER and HER catalyst displayed high current and potential stability for a period of 12 h. This approach is seen as the right track of making water electrolysis for hydrogen energy feasible through provision of low-energy requirement for the electrolytic process. Therefore, CdFe2O4 is a potential water splitting catalyst for hydrogen evolution which is a clean fuel and an antidote for world dependence on fossil fuel for energy generation.

Бірта Г., Горячова О., Бургу Ю. МІКРОБІОЛОГІЧНІ КРИТЕРІЇ БЕЗПЕЧНОСТІ СОРТОВИХ ЯБЛУЧНИХ СОКІВ ПРИ ВИРОБНИЦТВІ

One of the important topics in controlling the safety of food and beverages is risk assessment, ie the possibility of deterioration of human health when consumed. The problem of microbiological contamination of food is now quite acute, especially in the context of the mandatory introduction of a security system. Studies of the microbiological safety of certain exported food products intended for consumption in the domestic market are widely conducted, but to a large extent the study of domestic raw materials for juice products, in terms of varietal characteristics of raw materials remains open. The purpose of the study was to study the microbiological criteria for the safety of apple juice in the production in terms of varietal characteristics of raw materials (apples). Standard methods are used to determine microbiological criteria for product safety. The article describes the microbiological safety criteria for pasteurized apple juice. The quality of products according to microbiological indicators is determined. The results of assessment of compliance with national and European requirements for microbiological safety for this type of product are presented.

DEVELOPMENT OF NEW TYPES OF MEAT AND FISH SEMI-FINISHED PRODUCTS OF HERODIETIC NUTRITION

Health is a unique value of humanity, especially in the global era of the COVID-19 pandemic, so improving the health of the population is the main task of a society that strives for prosperity and sustainable development. The food industry is critical to humanity and the planet. The question of the expediency of a balanced diet to ensure the quality and prolong the duration of socially active life is becoming increasingly important in almost all countries of the world. The creation of new food is due to many factors: global climate change, leading to certain problems in crop and livestock, the general deterioration of human health associated with new technologies for growing, processing and production of food, which is a prerequisite for inventing preventive or curative food and beverages. The meat industry, as the most important branch of the national economy, provides the country’s population with one of the main sources of protein. With its multi-vector development, one of the important directions is the production of frozen products, including meat and meat-containing cut semi-finished products. Despite the unstable economic situation in the country and low purchasing power of the population, especially the elderly, among the main factors shaping the dynamics of this segment is the deepening of intersectoral cooperation, namely in the meat industry – expanding the range of frozen semi-finished products. Given the above, a timely and promising direction is the development of recipes and improving the technology of production of meat and fish semi-finished products using meat (turkey fillet), fish (hake), vegetable raw materials and blends of oils (high oleic sunflower and grape seed oils). According to the results of research, recipes were developed and the nutritional value of the new product was calculated.