Depression In Non-clinical Populations Research Articles

An Open-Source Platform for Real-Time Preliminary Diagnosis amongst Adults using Data Analytics

Depression can be defined as a mental health disorder characterized by persistently depressed mood, loss of interest in activities, causing significant impairment in daily life. Technical intervention to screen depression in non-clinical population which records, classify depression on the basis of severity and provide features or predictors that discriminate the classification of depression among non-clinical population comprising of college students is the main area of the study. Beck Depression Inventory – II (BDI-II), as per Diagnostic and Statistical manual of Mental disorder (DSM IV) is used to screen depression and its severity. Indicators are determined on the basis of how well the features or predictors can discriminate the classes of depression severity. Providing quality indicators which help in supporting the process can be considered as symptoms for screening depression. Descriptive analytics is used in order to find the underlying pattern of the responses captured, factor analysis groups variables on the basis of correlation between patterns of the responses to reduce dimension. The approach for supervised descriptive analysis method that takes BDI-II questions as features and refine the features using information gain and linear discriminant analysis as feature selection algorithm. The classification of severity of depression is done using Support vector machine (SVM)..

Recommendations of the treatment-resistant depression expert center network for promoting tobacco smoking cessation based on the results from the real-world FACE-TRD national cohort

BackgroundTobacco smoking has been associated with suicide, impulsivity and depression in non-clinical populations with differences across sexes. ObjectiveTo determine the role of tobacco smoking in Treatment-Resistant Depression (TRD) according to sex in a precision-medicine approach. MethodThe FACE-TRD cohort is a national cohort of TRD patients recruited in 13 resistant depression expert centers between 2014 and 2021 and followed-up at 6 months. A standardized one-day long comprehensive battery was carried out, including trained-clinician and patient-reported outcomes, and patients were reevaluated at 6 months on their smoking and psychiatric hospitalization outcomes. Results355 TRD participants were included (222 women). The smoking rate was much higher in TRD women compared to the French general population (34% vs 24%) while it was comparable for men (approximately 29%). In multivariate analyses, compared to non-smoking women, female smokers had significantly increased number of lifetime psychiatric hospitalizations (standardized beta B = 0.232, p = 0.014) and electro-convulsive therapy (adjusted odds ratio (aOR) = 2.748, p = 0.005), increased suicidal ideations (aOR = 4.047, p = 0.031), history of suicide attempt (aOR = 1.994, p = 0.033), and increased impulsivity (B = 0.210, p = 0.006) and were more frequently treated by benzodiazepines (aOR = 1.848, p = 0.035) and third- or fourth-line TRD treatments (antipsychotics aOR = 2.270, p = 0.006, mood stabilizers aOR = 2.067 p = 0.044). Tobacco smoking at baseline was predictive of psychiatric hospitalization within 6 months in persistent smoking women (aOR = 2.636, p = 0.031). These results were not replicated in men, for whom tobacco smoking was only associated with increased clinician-rated and self-reported depressive symptoms (respectively B = 0.207, p = 0.022 and B = 0.184, p = 0.048). The smoking cessation rate at 6 months was higher in women than in men (12% vs. 7%). No patient was administered nicotine substitute or varenicline at the two timepoints. InterpretationCombining these results and those of the literature, we recommend that active tobacco cessation should be promoted in TRD to improve depression, suicide and impulsivity especially in women. Female smokers appear as a specific population with heavier mental health outcomes that should be specifically addressed.

Testing the Metacognitive Model of Rumination and Depression in Non-clinical Population: New Data about PBRS and NBRS Scales

Rumination is a maladaptive emotion regulation strategy linked to depression. An intriguing question is why some people tend to use it. The metacognitive model proposes that people having positive metacognitive beliefs (“ruminating helps me cope”) are more prone to engage in ruminative processes. On the other hand, negative metacognitive beliefs (“rumination is uncontrollable”) lead to negative appraisals about rumination, increasing depressive symptomatology. Two scales assess both of these core beliefs: the Positive and Negative Beliefs about Rumination Scales (PBRS and NBRS). While they have been widely used, few studies have examined their factor structure and psychometric properties. Preliminary support has also been provided for the metacognitive model of rumination and depression, but contrary results exist about the specific contributing negative beliefs. In this study, we aimed, first, to add new evidence of the factor structure and psychometric properties of the PBRS and NBRS in a non-clinical population and, second, to test the metacognitive model using structural equation modeling (SEM). We also add the Spanish version of these scales. The participants included 427 individuals from the general population. We confirmed the one-factor structure of the PBRS and found evidence for a three-factor structure of the NBRS (uncontrollability, harm and social consequences), differing from the two-factor structure found in previous studies. SEM analyses showed that positive beliefs were associated to rumination and negative beliefs about social consequences partially mediated the relations among rumination and depression. Our findings show new data about the validity of the two scales and suggest the utility of considering a three-factor model of the NBRS.

Review: Effectiveness of mindfulness in improving mental health symptoms of children and adolescents: a meta-analysis.

Mindfulness-based interventions (MBIs) are increasingly used in the management of various mental health disorders in children and adolescents. However, there is limited evidence about the efficacy of various interventions used. A systematic review was performed to examine the effects of different MBIs on mental health symptoms and quality of life in both clinical and nonclinical samples of children and adolescents using data from only randomized control trials. The studies were also assessed for quality. Based on the type of MBI, study population, and control arm we had three comparisons for meta-analyses. Fifteen studies were included in the qualitative analysis but only 11 trials with comparable interventions and controls were included for meta-analyses. Mindfulness-based stress reduction/mindfulness-based cognitive therapy arm was more effective than nonactive control in the nonclinical populations. Acceptance commitment therapy was comparable to active treatments in patients in the clinical range. Other MBIs were also effective improving anxiety and stress but not depression in nonclinical populations compared to nonactive control. Mindfulness-based interventions can be effective in children and adolescents with mental health symptoms. As there were significant limitations these results must be interpreted with caution.

Depressive Rumination and Social Problem Solving in Japanese University Students.

The relationship between depressive rumination and dimensions of social problem solving were investigated in a Japanese, nonclinical population. University students (N = 227) completed the Beck Depression Inventory-Second Edition, Ruminative Responses Scale, Means-Ends Problem-Solving (MEPS) test, and Social Problem-Solving Inventory-Revised Short Version (SPSI-R:S). Results indicated that after controlling for depression, trait rumination, especially its brooding subcomponent, was positively correlated with negative problem orientation and avoidance style. Unexpectedly, trait rumination was weakly but positively associated with an effective problem-solving style, as assessed by the SPSI-R:S and MEPS. These findings suggest that one pathway through which rumination leads to depression in nonclinical populations could be through increasing negative problem orientation and avoidance problem-solving style. Results also suggested that reflection, compared to brooding, was positively associated with positive problem orientation and more strongly associated with rationale problem-solving style. These findings suggest that reflection leads to active problem solving.

The Paranoia of Everyday Life: Some Personal, Psychological, and Pastoral Thoughts

Freud, early in his writings, makes the argument that paranoia results from the repression of distressing memories, paralleling hysteria and obsessional neurosis. The difference, however, is that paranoia makes use of a special psychic mechanism—projection—whereas hysteria makes use of conversion into somatic innervations and obsessional neurosis makes use of substitution or displacement. Drawing on recent research in paranoia, which suggests that feelings of paranoia are quite common among non-clinical populations, perhaps even as common as feelings of anxiety and depression in non-clinical populations, I suggest that paranoia “in everyday life”—that is, paranoia among non-clinical or so-called “normal” populations—results from the suppression (rather than the repression) of distressing thoughts (rather than memories). The mechanism of projection is still at work, but because paranoia in everyday life results from suppression rather than repression, it is much less severe but also much more common. I have followed the logic of Freud’s writings and I have used the method of introspection to come to this conclusion. I argue that pastors and other such persons would do well in knowing something about paranoia so that (1) they can deal more compassionately with those struggling with paranoia and so that (2) they can deal more compassionately with themselves, since it is likely, I believe, that many pastors often struggle with feelings of paranoia. I note several strategies for coping with paranoia as I deal with religious and psychological aspects of paranoia.

A systematic review of longitudinal studies on the association between depression and smoking in adolescents

BackgroundIt is well-established that smoking and depression are associated in adolescents, but the temporal ordering of the association is subject to debate.MethodsLongitudinal studies in English language which reported the onset of smoking on depression in non clinical populations (age 13-19) published between January 1990 and July 2008 were selected from PubMed, OVID, and PsychInfo databases. Study characteristics were extracted. Meta-analytic pooling procedures with random effects were used.ResultsFifteen studies were retained for analysis. The pooled estimate for smoking predicting depression in 6 studies was 1.73 (95% CI: 1.32, 2.40; p < 0.001). The pooled estimate for depression predicting smoking in 12 studies was 1.41 (95% CI: 1.21, 1.63; p < 0.001). Studies that used clinical measures of depression were more likely to report a bidirectional effect, with a stronger effect of depression predicting smoking.ConclusionEvidence from longitudinal studies suggests that the association between smoking and depression is bidirectional. To better estimate these effects, future research should consider the potential utility of: (a) shorter intervals between surveys with longer follow-up time, (b) more accurate measurement of depression, and (c) adequate control of confounding.