Purpose. The paper concerns additional geological appraisal and identification of extra localization criteria of cupriferous mineralization of a stratiform type. The research is intended to define physical and geological factors influencing sandstone distribution within the north-end of Zhezkazgan synclinal in the Central Kazakhstan. Methods. A complex analysis of geological and mineralogical, geophysical, and geochemical data was carried out relying upon the information obtained from deep-hole wells. Modern methods to process and interpret the field data were applied. The analysis involved lithological dismemberment of the productive Taskuduk suite as well as determination of sulfide mine-ralization zone boundaries. Findings. The research has shown that the productive levels reach down to 1500-m depth. The data interpretation has helped specify the geological structure and develop a model of ore-promising bodies of cupriferous sandstones at great depth. The applied complex data analysis has increased potential to prospect new loci of productive cupriferous sandstone deposits of Zhezkazgan type. Originality. The research has contributed significantly to understanding of the physical and geological factors influencing the copper ore distribution in deep layers. New physical and geological criteria, determining deep copper mineralization localization, have been identified which were not considered by earlier similar studies. Practical implications. The obtained new data as well as the developed methods are important while deep drilling planning and implementing to identify promising copper mineralization sites. The findings may be used to optimize exploration within the north-end of Zhezkazgan synclinal, and other districts having analogous geological conditions.