ABSTRACT Dentigerous cyst of mandible is a rare entity in routine clinical practice. A dentigerous or follicular cyst is formed from the accumulation of fluid between the reduced enamel epithelium and the completely formed tooth crown or in the layers of the reduced enamel epithelium. Pulp necrosis is a commonly observed sequel in traumatized primary teeth and is one of the possible etiologic factors for the development of dentigerous teeth. The dentigerous cyst is found in children and adolescents; the highest incidence is in the second and third decades. This article reports the case of a dentigerous cyst associated with the germ of a permanent mandibular right lower canine. The therapeutic approach included endodontic treatment of the primary tooth and marsupialization of the lesion. In conclusion, with proper case selection, marsupialization might be a good treatment option for conservative management of dentigerous cysts. How to cite this article Aggarwal P, Sohal BS, Uppal KS. Dentigerous Cyst of Mandible. Int J Head Neck Surg 2013; 4(2):95-97.