The pathways and mixing in dense water overflows have been addressed in a range of numerical studies based on the DOME (Dynamics of Overflow Mixing and Entrainment) setup. These studies are motivated by overflows such as the flow of dense and cold water over the ridge between Iceland and Scotland. The main route of this water is through the Faroe-Shetland channel and further through the Faroe Bank Channel. After leaving the Faroe Bank Channel, the dense water continues along the slope along the Iceland-Faroe Ridge. Across this ridge there is also a strong flow of Atlantic water that may affect the pathway and mixing in the dense plume. In the DOME investigations, the slope steepness is assumed to be constant and there is no active background flow in the ambient water masses above the dense plume. With the situation along the Iceland-Faroe Ridge in mind, the setup from the DOME experiment is adjusted to study the effects of i) the slope profile, ii) flows crossing the slope on top of the along-slope flow of dense water, and iii) the topography near the overflow channel of dense water. It is found that the rate of descent is depending on slope steepness, and for a curved slope going from flat on top of a ridge to much steeper away from the ridge, dense water parcels near the ridge top or crest will sink slower than the faster flowing dense water further down along the slope. A cross-flow over the ridge, mimicking the flow of Atlantic water over the Iceland-Faroe Ridge, will force stronger mixing between the dense water and the ambient water above and dense water mixed up into the surface water can be allowed to flow out across the ridge. Furthermore, the dynamical situation along the slope will change and fluid parcels in the deeper part of the plume can experience a faster rate of descent. By removing a barrier in the topography downstream of the overflow channel, dense water can be steered towards the ridge and the starting point of the center of mass of the descending overflow water will be higher up on the slope.