Abandoned quarries are a relatively common form of anthropogenic relief. The rocks disturbed by previous mining activities could foster conditions favourable for future dynamic geomorphic processes on quarry faces. Nevertheless, the activity of such processes, particularly that of rockfall, has not yet been studied in detail. This is of particular importance because human infrastructure is often still present in abandoned quarries, and rockfall can cause distinct natural hazards in such conditions. This study focuses on a multidisciplinary analysis of rockfall in selected abandoned quarry in the region of the Carpathians. A dendrogeomorphic analysis of 807 tree-ring series from 130 disturbed trees occupying the talus provided evidence of 264 tree injuries caused by falling rocks during the last 22 years. The reconstructed frequency of rockfall in quarries is several times higher than that of rockfall from natural localities within the studied region but also in Europe. Next, the seasonal dating of rockfall hits to trees displayed the prominence of such events during the tree dormancy period (ca. October to April), suggesting freeze–thaw cycles as the main trigger (the same as for natural localities in the region). Three species of broad-leaved trees of comparable age were used for the reconstruction, but no differences among the species were detected. The number of rockfall hits on tree trunks decreased significantly with increasing distance from the rockfall source zone, suggesting strong gradation of rockfall activity, compared to natural localities. Generally, the multidisciplinary results suggest very unstable conditions of rocks in abandoned quarries, predisposing them to frequent gravitational events. In contrast, ecological succession after mining termination gradually offers a protective function of trees.